Potassium in PDB 7nht: AKIRIN2 Bound Human Proteasome

All present enzymatic activity of AKIRIN2 Bound Human Proteasome:
3.4.25.1;

The binding sites of Potassium atom in the AKIRIN2 Bound Human Proteasome (pdb code 7nht). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the AKIRIN2 Bound Human Proteasome, PDB code: 7nht:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the AKIRIN2 Bound Human Proteasome


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of AKIRIN2 Bound Human Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ G:K301 b:60.3 occ:1.00 OG1 G:THR14 2.6 54.7 1.0 O G:MET131 2.6 54.8 1.0 O G:ASN128 2.7 53.6 1.0 O G:TYR125 2.8 51.7 1.0 CB G:THR14 3.5 54.7 1.0 C G:MET131 3.8 54.8 1.0 C G:ASN128 3.8 53.6 1.0 C G:TYR125 4.0 51.7 1.0 CD G:PRO133 4.1 52.1 1.0 CA G:ALA129 4.2 55.4 1.0 CA G:ARG132 4.3 52.3 1.0 CG2 G:THR14 4.4 54.7 1.0 N G:THR14 4.5 54.7 1.0 N G:ALA129 4.5 55.4 1.0 C G:ALA129 4.5 55.4 1.0 CA G:THR126 4.5 51.5 1.0 N G:ARG132 4.6 52.3 1.0 CG G:PRO133 4.6 52.1 1.0 CA G:THR14 4.6 54.7 1.0 N G:PRO133 4.7 52.1 1.0 C G:ARG132 4.7 52.3 1.0 N G:THR126 4.7 51.5 1.0 N G:MET131 4.7 54.8 1.0 O G:ALA129 4.7 55.4 1.0 C G:THR126 4.8 51.5 1.0 CA G:MET131 4.9 54.8 1.0 SD G:MET131 4.9 54.8 1.0 N G:ASN128 5.0 53.6 1.0 CA G:ASN128 5.0 53.6 1.0

Potassium binding site 2 out of 3 in the AKIRIN2 Bound Human Proteasome


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of AKIRIN2 Bound Human Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ L:K301 b:60.0 occ:1.00 O L:THR189 2.9 56.2 1.0 O L:ALA183 3.0 53.8 1.0 O L:ASP186 3.1 54.7 1.0 C L:ALA183 3.9 53.8 1.0 CA L:ALA183 4.0 53.8 1.0 C L:THR189 4.0 56.2 1.0 O L:VAL187 4.2 54.2 1.0 C L:ASP186 4.2 54.7 1.0 CB L:ALA183 4.2 53.8 1.0 CA L:VAL187 4.3 54.2 1.0 NH2 L:ARG28 4.3 55.6 1.0 C L:VAL187 4.3 54.2 1.0 N L:THR189 4.6 56.2 1.0 NH1 L:ARG28 4.8 55.6 1.0 N L:VAL187 4.8 54.2 1.0 CA L:GLY190 4.9 57.1 1.0 O L:ARG211 4.9 56.4 1.0 N L:GLY190 4.9 57.1 1.0 CA L:THR189 4.9 56.2 1.0 OXT L:ASP213 5.0 60.2 1.0 CG2 L:THR189 5.0 56.2 1.0 CZ L:ARG28 5.0 55.6 1.0

Potassium binding site 3 out of 3 in the AKIRIN2 Bound Human Proteasome


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of AKIRIN2 Bound Human Proteasome within 5.0Å range: probe atom residue distance (Å) B Occ N:K301 b:60.7 occ:1.00 O N:SER170 2.8 53.1 1.0 O N:MET164 2.9 53.7 1.0 O N:ASP167 2.9 53.3 1.0 NH1 N:ARG19 3.2 52.6 1.0 C N:ASP167 3.8 53.3 1.0 CA N:GLY168 3.9 53.2 1.0 C N:SER170 4.1 53.1 1.0 C N:MET164 4.1 53.7 1.0 CZ N:ARG19 4.2 52.6 1.0 O N:GLY168 4.2 53.2 1.0 C N:GLY168 4.3 53.2 1.0 N N:GLY168 4.3 53.2 1.0 O N:GLU165 4.5 53.1 1.0 NH2 N:ARG19 4.6 52.6 1.0 N N:SER170 4.7 53.1 1.0 C N:GLU165 4.8 53.1 1.0 CA N:GLY171 4.8 52.9 1.0 N N:GLY171 4.9 52.9 1.0 CA N:MET164 4.9 53.7 1.0 CA N:GLU165 4.9 53.1 1.0 N N:GLU165 5.0 53.1 1.0

M.T.De Almeida, M.Hinterndorfer, H.Brunner, I.Grishkovskaya, K.Singh, A.Schleiffer, J.Jude, S.Deswal, R.Kalis, M.Vunjak, T.Lendl, R.Imre, E.Roitinger, T.Neumann, S.Kandolf, M.Schutzbier, K.Mechtler, G.Versteeg, D.Haselbach, J.Zuber. AKIRIN2 Controls the Nuclear Import of Proteasomes in Vertebrates Nature 2021.
ISSN: ESSN 1476-4687