Potassium in PDB 7mub: Kcsa Open Gate E71V Mutant in Potassium

The structure of Kcsa Open Gate E71V Mutant in Potassium, PDB code: 7mub was solved by A.Rohaim, J.Li, M.Weingarth, B.Roux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.00
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	139.449, 139.449, 69.219, 90, 90, 90
R / Rfree (%)	19.7 / 26

The binding sites of Potassium atom in the Kcsa Open Gate E71V Mutant in Potassium (pdb code 7mub). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Kcsa Open Gate E71V Mutant in Potassium, PDB code: 7mub:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Kcsa Open Gate E71V Mutant in Potassium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Kcsa Open Gate E71V Mutant in Potassium within 5.0Å range: probe atom residue distance (Å) B Occ C:K201 b:143.7 occ:0.25 O C:THR75 2.5 132.2 1.0 O C:VAL76 2.8 126.9 1.0 C C:THR75 3.5 125.6 1.0 C C:VAL76 3.7 130.4 1.0 OG1 C:THR75 3.8 113.7 1.0 O C:HOH301 3.8 91.5 0.2 CA C:VAL76 4.1 128.0 1.0 N C:VAL76 4.2 118.3 1.0 CB C:THR75 4.5 124.0 1.0 CA C:THR75 4.5 126.7 1.0 N C:GLY77 4.8 127.8 1.0

Potassium binding site 2 out of 2 in the Kcsa Open Gate E71V Mutant in Potassium


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Kcsa Open Gate E71V Mutant in Potassium within 5.0Å range: probe atom residue distance (Å) B Occ C:K202 b:148.2 occ:0.25 O C:TYR78 2.8 129.3 1.0 O C:GLY77 2.9 112.5 1.0 C C:TYR78 3.5 117.3 1.0 C C:GLY77 4.1 122.4 1.0 O C:HOH301 4.1 91.5 0.2 CA C:TYR78 4.2 118.8 1.0 N C:GLY79 4.3 109.1 1.0 CA C:GLY79 4.4 108.5 1.0 N C:TYR78 4.5 116.8 1.0

A.Rohaim, B.J.A.Vermeulen, J.Li, F.Kummerer, F.Napoli, L.Blachowicz, J.Medeiros-Silva, B.Roux, M.Weingarth. A Distinct Mechanism of C-Type Inactivation in the Kv-Like Kcsa Mutant E71V. Nat Commun V. 13 1574 2022.
ISSN: ESSN 2041-1723
PubMed: 35322021
DOI: 10.1038/S41467-022-28866-9