Potassium in PDB 7jzb: Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde

All present enzymatic activity of Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde:
4.3.3.7;

The structure of Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde, PDB code: 7jzb was solved by A.J.Board, R.C.J.Dobson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.97 / 1.93
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	121.143, 121.143, 111.23, 90, 90, 120
R / Rfree (%)	15.1 / 17.8

The binding sites of Potassium atom in the Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde (pdb code 7jzb). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde, PDB code: 7jzb:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde within 5.0Å range: probe atom residue distance (Å) B Occ A:K301 b:26.7 occ:1.00 O A:VAL154 2.6 29.4 1.0 O A:ILE157 2.7 20.5 1.0 O A:HOH594 2.7 34.7 1.0 O A:ALA152 2.7 20.7 1.0 O A:HOH590 2.9 49.1 1.0 O A:LYS155 3.2 25.6 1.0 C A:VAL154 3.7 29.4 1.0 C A:ALA152 3.7 22.5 1.0 C A:ILE157 3.8 21.4 1.0 C A:LYS155 3.8 30.2 1.0 CA A:LYS155 4.1 31.0 1.0 N A:ILE157 4.2 20.7 1.0 N A:LYS155 4.3 32.4 1.0 CA A:ALA152 4.4 21.4 1.0 CA A:ILE157 4.5 21.2 1.0 N A:VAL154 4.5 26.8 1.0 C A:LYS153 4.6 30.2 1.0 N A:ASN156 4.6 22.9 1.0 N A:ILE158 4.7 19.1 1.0 CA A:ILE158 4.7 21.4 1.0 N A:LYS153 4.7 22.8 1.0 CA A:VAL154 4.8 25.9 1.0 O A:LYS153 4.9 27.4 1.0 CB A:ILE157 4.9 20.4 1.0 CA A:LYS153 4.9 25.8 1.0 CD1 A:PHE181 4.9 20.5 1.0

Potassium binding site 2 out of 2 in the Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Dihydrodipicolinate Synthase S48W with Lysine in the Allosteric Site, and Pyruvate and Succinic Semi-Aldehyde within 5.0Å range: probe atom residue distance (Å) B Occ B:K301 b:33.6 occ:1.00 O B:HOH563 2.6 44.7 1.0 O B:VAL154 2.6 31.0 1.0 O B:ILE157 2.6 27.5 1.0 O B:ALA152 2.7 28.8 1.0 O B:LYS155 3.1 31.9 1.0 C B:ILE157 3.7 27.2 1.0 C B:LYS155 3.7 36.6 1.0 C B:VAL154 3.7 32.5 1.0 C B:ALA152 3.7 28.9 1.0 N B:ILE157 4.1 26.4 1.0 CA B:LYS155 4.1 41.9 1.0 CA B:ILE157 4.4 25.5 1.0 N B:LYS155 4.4 35.0 1.0 CA B:ALA152 4.4 27.1 1.0 N B:VAL154 4.5 33.5 1.0 C B:LYS153 4.5 38.4 1.0 N B:ASN156 4.6 31.3 1.0 N B:ILE158 4.6 26.7 1.0 CA B:ILE158 4.7 27.1 1.0 N B:LYS153 4.7 26.5 1.0 CA B:VAL154 4.8 33.4 1.0 O B:LYS153 4.9 34.4 1.0 CB B:ILE157 4.9 25.5 1.0 CA B:LYS153 4.9 33.1 1.0 C B:ASN156 4.9 29.4 1.0 CD1 B:PHE181 5.0 30.9 1.0 CG2 B:ILE158 5.0 37.5 1.0

A.J.Board, R.C.J.Dobson. Mapping the Uncharted Water Channel of Dhdps To Be Published.