Potassium in PDB 7e20: Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State

All present enzymatic activity of Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State:
7.2.2.13;

The structure of Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Potassium atom in the Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State (pdb code 7e20). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State, PDB code: 7e20:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State within 5.0Å range: probe atom residue distance (Å) B Occ A:K1101 b:34.4 occ:1.00 OD1 A:ASP811 2.7 32.4 1.0 OG A:SER782 2.9 26.0 1.0 OD1 A:ASN783 3.0 27.1 1.0 O A:THR779 3.2 26.9 1.0 CG A:ASP811 3.5 32.4 1.0 OE1 A:GLU786 3.8 26.5 1.0 K A:K1102 3.9 29.0 1.0 CG2 A:THR779 4.0 26.9 1.0 OD2 A:ASP811 4.1 32.4 1.0 CG A:ASN783 4.1 27.1 1.0 N A:ASN783 4.1 27.1 1.0 OD2 A:ASP815 4.2 32.3 1.0 CB A:SER782 4.2 26.0 1.0 CB A:ASP811 4.2 32.4 1.0 C A:THR779 4.2 26.9 1.0 C A:SER782 4.3 26.0 1.0 O A:SER782 4.6 26.0 1.0 CA A:ASN783 4.6 27.1 1.0 CD A:GLU786 4.6 26.5 1.0 CA A:PRO333 4.7 32.8 1.0 OE2 A:GLU786 4.7 26.5 1.0 CA A:THR779 4.7 26.9 1.0 CA A:SER782 4.8 26.0 1.0 CB A:PRO333 4.8 32.8 1.0 CB A:ASN783 4.9 27.1 1.0

Potassium binding site 2 out of 3 in the Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State within 5.0Å range: probe atom residue distance (Å) B Occ A:K1102 b:29.0 occ:1.00 OE2 A:GLU786 2.9 26.5 1.0 O A:VAL332 2.9 33.1 1.0 OD1 A:ASN783 3.1 27.1 1.0 OD2 A:ASP811 3.2 32.4 1.0 O A:ALA330 3.3 30.0 1.0 O A:VAL329 3.4 29.8 1.0 OE1 A:GLU334 3.5 33.2 1.0 C A:ALA330 3.7 30.0 1.0 CD A:GLU786 3.9 26.5 1.0 C A:VAL332 3.9 33.1 1.0 K A:K1101 3.9 34.4 1.0 CG A:ASP811 3.9 32.4 1.0 CG A:ASN783 4.1 27.1 1.0 OD1 A:ASP811 4.1 32.4 1.0 CA A:ALA330 4.1 30.0 1.0 OE1 A:GLU786 4.2 26.5 1.0 CA A:PRO333 4.4 32.8 1.0 N A:PRO333 4.4 32.8 1.0 N A:ASN331 4.5 31.7 1.0 N A:VAL332 4.5 33.1 1.0 CD A:GLU334 4.5 33.2 1.0 C A:VAL329 4.5 29.8 1.0 CG2 A:ILE807 4.6 28.5 1.0 C A:ASN331 4.6 31.7 1.0 ND2 A:ASN783 4.7 27.1 1.0 N A:GLU334 4.8 33.2 1.0 OE2 A:GLU334 4.8 33.2 1.0 N A:ALA330 4.8 30.0 1.0 CA A:VAL332 4.8 33.1 1.0 CA A:ASN783 4.9 27.1 1.0 CA A:ASN331 4.9 31.7 1.0

Potassium binding site 3 out of 3 in the Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Cryo Em Structure of A K+-Bound Na+,K+-Atpase in the E2 State within 5.0Å range: probe atom residue distance (Å) B Occ A:K1103 b:46.9 occ:1.00 OD2 A:ASP747 2.6 40.9 1.0 O A:LEU725 3.3 42.7 1.0 CG A:ASP747 3.6 40.9 1.0 O A:ALA728 3.6 41.0 1.0 O A:LYS726 3.9 44.8 1.0 OD1 A:ASP747 4.0 40.9 1.0 N A:GLY731 4.3 39.0 1.0 C A:LYS726 4.4 44.8 1.0 CA A:LYS726 4.4 44.8 1.0 O A:ALA745 4.4 45.4 1.0 C A:LEU725 4.5 42.7 1.0 O A:ASP729 4.6 39.8 1.0 C A:ALA728 4.7 41.0 1.0 CB A:ASP747 4.8 40.9 1.0 CA A:ILE730 4.8 37.7 1.0 C A:ASP729 4.9 39.8 1.0 C A:ILE730 4.9 37.7 1.0 N A:LYS726 4.9 44.8 1.0 N A:ASP747 5.0 40.9 1.0

Y.Guo, Y.Zhang, R.Yan, B.Huang, F.Ye, L.Wu, X.Chi, Y.Shi, Q.Zhou. Cryo-Em Structures of Recombinant Human Sodium-Potassium Pump Determined in Three Different States. Nat Commun V. 13 3957 2022.
ISSN: ESSN 2041-1723
PubMed: 35803952
DOI: 10.1038/S41467-022-31602-Y