Potassium in PDB 7cn1: Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole

The binding sites of Potassium atom in the Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole (pdb code 7cn1). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole, PDB code: 7cn1:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole within 5.0Å range: probe atom residue distance (Å) B Occ A:K1101 b:30.0 occ:1.00 O C:VAL625 2.7 32.7 1.0 O B:VAL625 2.7 36.2 1.0 O D:VAL625 2.7 32.0 1.0 O A:VAL625 2.8 35.3 1.0 C D:VAL625 3.6 32.0 1.0 C A:VAL625 3.7 35.3 1.0 C C:VAL625 3.7 32.7 1.0 C B:VAL625 3.7 36.2 1.0 O A:SER624 3.8 42.4 1.0 O D:SER624 3.9 40.6 1.0 CA D:VAL625 3.9 32.0 1.0 O B:SER624 3.9 39.0 1.0 K A:K1102 4.0 30.0 1.0 CA A:VAL625 4.0 35.3 1.0 CA C:VAL625 4.0 32.7 1.0 CA B:VAL625 4.2 36.2 1.0 O C:SER624 4.2 39.9 1.0 C A:SER624 4.4 42.4 1.0 C D:SER624 4.4 40.6 1.0 K C:K1101 4.4 30.0 1.0 N D:VAL625 4.5 32.0 1.0 N A:VAL625 4.6 35.3 1.0 C B:SER624 4.7 39.0 1.0 C C:SER624 4.7 39.9 1.0 N D:GLY626 4.7 32.4 1.0 N C:VAL625 4.7 32.7 1.0 N A:GLY626 4.8 36.1 1.0 N B:GLY626 4.8 37.3 1.0 N B:VAL625 4.8 36.2 1.0 N C:GLY626 4.8 34.5 1.0

Potassium binding site 2 out of 3 in the Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole within 5.0Å range: probe atom residue distance (Å) B Occ A:K1102 b:30.0 occ:1.00 O D:GLY626 2.8 32.4 1.0 O A:GLY626 2.8 36.1 1.0 O B:GLY626 3.0 37.3 1.0 O C:GLY626 3.0 34.5 1.0 O A:VAL625 3.6 35.3 1.0 O D:VAL625 3.6 32.0 1.0 O C:VAL625 3.8 32.7 1.0 O B:VAL625 3.9 36.2 1.0 C D:GLY626 3.9 32.4 1.0 C A:GLY626 3.9 36.1 1.0 K A:K1101 4.0 30.0 1.0 C B:GLY626 4.1 37.3 1.0 C C:GLY626 4.1 34.5 1.0 CA A:GLY626 4.5 36.1 1.0 CA D:GLY626 4.6 32.4 1.0 CA B:GLY626 4.6 37.3 1.0 C A:VAL625 4.7 35.3 1.0 C D:VAL625 4.7 32.0 1.0 CA C:GLY626 4.8 34.5 1.0 C C:VAL625 4.9 32.7 1.0 N D:PHE627 5.0 37.4 1.0 C B:VAL625 5.0 36.2 1.0

Potassium binding site 3 out of 3 in the Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Cryo-Em Structure of K+-Bound Herg Channel in the Presence of Astemizole within 5.0Å range: probe atom residue distance (Å) B Occ C:K1101 b:30.0 occ:1.00 O D:SER624 3.0 40.6 1.0 O B:SER624 3.0 39.0 1.0 O A:SER624 3.1 42.4 1.0 O C:SER624 3.1 39.9 1.0 OG C:SER624 3.5 39.9 1.0 OG D:SER624 3.5 40.6 1.0 OG B:SER624 3.5 39.0 1.0 OG A:SER624 3.6 42.4 1.0 CB A:SER624 3.8 42.4 1.0 CB D:SER624 3.9 40.6 1.0 CB B:SER624 4.0 39.0 1.0 CB C:SER624 4.0 39.9 1.0 C D:SER624 4.1 40.6 1.0 C A:SER624 4.1 42.4 1.0 C C:SER624 4.2 39.9 1.0 C B:SER624 4.2 39.0 1.0 K A:K1101 4.4 30.0 1.0 CA A:SER624 4.6 42.4 1.0 CA D:SER624 4.6 40.6 1.0 CA C:SER624 4.8 39.9 1.0 CA B:SER624 4.8 39.0 1.0

T.Asai, N.Adachi, T.Moriya, H.Oki, T.Maru, M.Kawasaki, K.Suzuki, S.Chen, R.Ishii, K.Yonemori, S.Igaki, S.Yasuda, S.Ogasawara, T.Senda, T.Murata. Cryo-Em Structure of K+-Bound Herg Channel Complexed with the Blocker Astemizole. Structure 2021.
ISSN: ISSN 0969-2126