Potassium in PDB 7c4i: High Resolution Structure of BRPF1 Bromodomain

Protein crystallography data

The structure of High Resolution Structure of BRPF1 Bromodomain, PDB code: 7c4i was solved by F.Wang, D.Lin, Z.Lv, B.Zhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.29 / 1.37
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 60.601, 60.601, 59.169, 90.00, 90.00, 120.00
R / Rfree (%) 16.6 / 19.4

Potassium Binding Sites:

The binding sites of Potassium atom in the High Resolution Structure of BRPF1 Bromodomain (pdb code 7c4i). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the High Resolution Structure of BRPF1 Bromodomain, PDB code: 7c4i:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 7c4i

Go back to Potassium Binding Sites List in 7c4i
Potassium binding site 1 out of 4 in the High Resolution Structure of BRPF1 Bromodomain


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of High Resolution Structure of BRPF1 Bromodomain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K201

b:23.2
occ:1.00
 NE A:ARG722 3.0 27.1 0.5
O A:HOH400 3.1 41.5 0.5
NH1 A:ARG722 3.4 23.0 0.5
CZ A:ARG722 3.5 27.5 0.5
CD A:ARG722 3.5 23.5 0.5
CD A:ARG722 3.9 26.4 0.5
CD1 A:LEU705 4.0 17.7 1.0
NE A:ARG722 4.0 23.9 0.5
NH2 A:ARG722 4.5 29.4 0.5
CG A:ARG722 4.5 20.4 0.5
CG2 A:VAL719 4.6 16.5 1.0
CG1 A:VAL719 4.6 16.5 1.0
CB A:ARG722 4.8 19.3 0.5
CA A:VAL719 4.8 14.7 1.0
CB A:VAL719 4.9 15.8 1.0
O A:HOH320 4.9 23.4 1.0
CB A:ARG722 5.0 20.7 0.5
O A:HOH380 5.0 18.1 1.0

Potassium binding site 2 out of 4 in 7c4i

Go back to Potassium Binding Sites List in 7c4i
Potassium binding site 2 out of 4 in the High Resolution Structure of BRPF1 Bromodomain


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of High Resolution Structure of BRPF1 Bromodomain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K202

b:23.1
occ:1.00
 O A:HOH411 2.6 35.8 1.0
O A:HOH380 3.3 18.1 1.0
CD A:ARG716 3.7 18.6 0.5
NE A:ARG716 3.8 19.2 0.5
NH2 A:ARG716 3.9 21.4 0.5
CZ A:ARG716 3.9 20.8 0.5
CE1 A:TYR715 4.0 13.4 1.0
CD A:ARG716 4.0 21.2 0.5
NE A:ARG716 4.0 22.1 0.5
CG2 A:VAL719 4.1 16.5 1.0
CZ A:ARG716 4.2 24.6 0.5
NH2 A:ARG716 4.4 25.0 0.5
CD1 A:TYR715 4.5 13.2 1.0
NH1 A:ARG716 4.7 21.4 0.5
CG1 A:VAL719 4.7 16.5 1.0
NH1 A:ARG716 4.8 25.5 0.5
CE A:LYS710 4.8 14.8 1.0
CB A:VAL719 4.8 15.8 1.0

Potassium binding site 3 out of 4 in 7c4i

Go back to Potassium Binding Sites List in 7c4i
Potassium binding site 3 out of 4 in the High Resolution Structure of BRPF1 Bromodomain


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of High Resolution Structure of BRPF1 Bromodomain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K203

b:17.7
occ:1.00
 O A:HOH346 3.7 17.7 1.0
ND2 A:ASN708 3.7 15.4 1.0
O A:HOH348 3.8 30.1 1.0
OH A:TYR665 3.8 20.0 1.0
CA A:CYS704 3.8 13.7 1.0
CB A:CYS704 3.9 13.5 1.0
SG A:CYS704 4.0 16.7 1.0
CG2 A:VAL657 4.0 23.2 1.0
CE1 A:TYR665 4.2 18.9 1.0
CE1 A:PHE653 4.3 19.8 1.0
CZ A:TYR665 4.5 18.6 1.0
N A:CYS704 4.5 13.2 1.0
CD2 A:PHE714 4.7 20.6 1.0
CD1 A:PHE653 4.7 18.1 1.0
CG A:ASN708 4.9 15.0 1.0
O A:ASN703 5.0 13.8 1.0
C A:ASN703 5.0 13.0 1.0

Potassium binding site 4 out of 4 in 7c4i

Go back to Potassium Binding Sites List in 7c4i
Potassium binding site 4 out of 4 in the High Resolution Structure of BRPF1 Bromodomain


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of High Resolution Structure of BRPF1 Bromodomain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K204

b:17.6
occ:0.80
 O A:GLN645 2.5 17.0 0.5
OD1 A:ASN651 2.6 22.5 1.0
O A:HOH420 2.6 39.7 1.0
O A:ASP648 2.7 15.6 1.0
O A:GLN645 2.8 16.7 0.5
O A:HOH333 2.8 21.8 1.0
C3 A:GOL208 3.4 62.2 1.0
C A:GLN645 3.6 16.4 0.5
C1 A:GOL208 3.6 60.9 1.0
C A:ASP648 3.7 15.3 1.0
CG A:GLN645 3.7 17.8 0.5
C A:GLN645 3.7 16.9 0.5
CG A:ASN651 3.7 20.6 1.0
C2 A:GOL208 4.1 62.4 1.0
CB A:ASP648 4.2 16.3 1.0
O3 A:GOL208 4.2 65.6 1.0
CA A:ASN651 4.3 17.8 1.0
CA A:GLN645 4.3 16.9 0.5
CB A:GLN645 4.4 18.1 0.5
CA A:ASP648 4.4 15.6 1.0
CA A:GLN645 4.5 16.4 0.5
N A:GLU646 4.5 16.5 0.5
N A:ASN651 4.5 16.9 1.0
CG A:ASP648 4.5 16.4 1.0
CB A:ASN651 4.5 19.6 1.0
O A:HOH399 4.6 31.0 1.0
OG A:SER654 4.6 23.6 1.0
OD2 A:ASP648 4.6 17.9 1.0
ND2 A:ASN651 4.6 21.2 1.0
N A:GLU646 4.6 17.0 0.5
CA A:GLU646 4.6 18.7 0.5
N A:THR649 4.6 16.1 1.0
NE2 A:GLN645 4.6 18.2 0.5
CB A:GLN645 4.6 17.4 0.5
CD A:GLN645 4.7 18.9 0.5
O A:HOH354 4.7 34.5 1.0
N A:ASP648 4.7 15.5 1.0
CA A:THR649 4.7 17.2 1.0
CA A:GLU646 4.8 19.2 0.5
O1 A:GOL208 4.9 65.0 1.0
O A:GLU646 4.9 18.7 0.5
C A:GLU646 4.9 18.0 0.5
NE2 A:GLN645 4.9 22.2 0.5

Reference:

F.Wang, D.Lin, Z.Lv, B.Zhu. High Resolution Structure of BRPF1 Bromodomain To Be Published.
Page generated: Mon Dec 14 02:45:19 2020

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