Potassium in PDB 7acc: Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
Protein crystallography data
The structure of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp), PDB code: 7acc
was solved by
R.Ebenhoch,
H.Nar,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
85.81 /
2.04
|
|
Space group
|
P 43 21 2
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
107.270,
107.270,
142.980,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
16.7 /
19.1
|
Potassium Binding Sites:
The binding sites of Potassium atom in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
(pdb code 7acc). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 10 binding sites of Potassium where determined in the
Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp), PDB code: 7acc:
Jump to Potassium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Potassium binding site 1 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 1 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K101
b:24.6
occ:0.55
|
O
|
A:GLN9
|
2.2
|
23.2
|
1.0
|
|
O
|
A:ARG11
|
2.3
|
24.3
|
1.0
|
|
O
|
A:VAL14
|
2.3
|
30.2
|
1.0
|
|
O
|
A:HOH219
|
2.3
|
25.1
|
1.0
|
|
OG1
|
A:THR8
|
2.5
|
25.1
|
1.0
|
|
C
|
A:ARG11
|
3.4
|
24.9
|
1.0
|
|
CG2
|
A:THR8
|
3.4
|
23.7
|
1.0
|
|
C
|
A:GLN9
|
3.5
|
23.6
|
1.0
|
|
C
|
A:VAL14
|
3.5
|
30.7
|
1.0
|
|
CB
|
A:THR8
|
3.5
|
24.1
|
1.0
|
|
N
|
A:GLN9
|
3.8
|
23.6
|
1.0
|
|
O
|
A:HOH227
|
4.0
|
29.6
|
1.0
|
|
CG1
|
A:VAL14
|
4.1
|
33.4
|
1.0
|
|
O
|
A:GLY15
|
4.1
|
29.2
|
1.0
|
|
N
|
A:ARG11
|
4.1
|
23.2
|
1.0
|
|
N
|
A:VAL14
|
4.2
|
28.9
|
1.0
|
|
N
|
A:MET12
|
4.3
|
25.2
|
1.0
|
|
CA
|
A:GLN9
|
4.3
|
23.5
|
1.0
|
|
C
|
A:ILE10
|
4.3
|
23.1
|
1.0
|
|
C
|
A:THR8
|
4.3
|
23.6
|
1.0
|
|
CA
|
A:MET12
|
4.3
|
25.6
|
1.0
|
|
CA
|
A:ARG11
|
4.3
|
24.2
|
1.0
|
|
CA
|
A:VAL14
|
4.4
|
30.7
|
1.0
|
|
C
|
A:GLY15
|
4.4
|
29.8
|
1.0
|
|
CA
|
A:THR8
|
4.4
|
23.4
|
1.0
|
|
N
|
A:ILE10
|
4.4
|
23.6
|
1.0
|
|
N
|
A:GLY15
|
4.4
|
30.6
|
1.0
|
|
CA
|
A:ILE10
|
4.5
|
23.6
|
1.0
|
|
C
|
A:MET12
|
4.5
|
26.5
|
1.0
|
|
CA
|
A:GLY15
|
4.5
|
30.2
|
1.0
|
|
O
|
A:PRO16
|
4.6
|
27.6
|
1.0
|
|
O
|
A:ILE10
|
4.7
|
22.6
|
1.0
|
|
O
|
A:MET12
|
4.8
|
27.4
|
1.0
|
|
CB
|
A:VAL14
|
4.9
|
32.9
|
1.0
|
|
Potassium binding site 2 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 2 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:K101
b:26.6
occ:0.72
|
O
|
B:GLN9
|
2.3
|
21.1
|
1.0
|
|
O
|
B:ARG11
|
2.3
|
24.7
|
1.0
|
|
O
|
B:VAL14
|
2.3
|
27.6
|
1.0
|
|
O
|
B:HOH230
|
2.4
|
27.2
|
1.0
|
|
OG1
|
B:THR8
|
2.4
|
24.3
|
1.0
|
|
C
|
B:ARG11
|
3.4
|
24.2
|
1.0
|
|
C
|
B:GLN9
|
3.5
|
21.4
|
1.0
|
|
CG2
|
B:THR8
|
3.5
|
23.2
|
1.0
|
|
C
|
B:VAL14
|
3.5
|
27.9
|
1.0
|
|
CB
|
B:THR8
|
3.5
|
22.7
|
1.0
|
|
N
|
B:GLN9
|
3.8
|
19.7
|
1.0
|
|
O
|
B:HOH235
|
3.9
|
29.0
|
1.0
|
|
CG1
|
B:VAL14
|
4.1
|
30.0
|
1.0
|
|
O
|
B:GLY15
|
4.1
|
26.3
|
1.0
|
|
N
|
B:ARG11
|
4.1
|
23.8
|
1.0
|
|
N
|
B:MET12
|
4.3
|
23.8
|
1.0
|
|
N
|
B:VAL14
|
4.3
|
27.6
|
1.0
|
|
C
|
B:ILE10
|
4.3
|
24.1
|
1.0
|
|
CA
|
B:GLN9
|
4.3
|
20.6
|
1.0
|
|
C
|
B:THR8
|
4.3
|
21.0
|
1.0
|
|
CA
|
B:MET12
|
4.3
|
24.7
|
1.0
|
|
CA
|
B:ARG11
|
4.3
|
23.5
|
1.0
|
|
C
|
B:GLY15
|
4.4
|
26.7
|
1.0
|
|
CA
|
B:VAL14
|
4.4
|
28.0
|
1.0
|
|
CA
|
B:THR8
|
4.4
|
21.0
|
1.0
|
|
N
|
B:GLY15
|
4.4
|
27.2
|
1.0
|
|
O
|
B:HOH229
|
4.4
|
38.6
|
1.0
|
|
N
|
B:ILE10
|
4.5
|
21.8
|
1.0
|
|
CA
|
B:GLY15
|
4.5
|
27.1
|
1.0
|
|
O
|
B:PRO16
|
4.5
|
26.2
|
1.0
|
|
C
|
B:MET12
|
4.5
|
25.2
|
1.0
|
|
CA
|
B:ILE10
|
4.5
|
23.2
|
1.0
|
|
O
|
B:ILE10
|
4.7
|
24.6
|
1.0
|
|
O
|
B:MET12
|
4.8
|
25.4
|
1.0
|
|
CB
|
B:VAL14
|
4.9
|
29.5
|
1.0
|
|
Potassium binding site 3 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 3 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 3 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K101
b:20.9
occ:0.59
|
O
|
C:GLN9
|
2.3
|
20.4
|
1.0
|
|
O
|
C:ARG11
|
2.3
|
22.7
|
1.0
|
|
O
|
C:VAL14
|
2.3
|
22.0
|
1.0
|
|
O
|
C:HOH234
|
2.3
|
22.5
|
1.0
|
|
OG1
|
C:THR8
|
2.5
|
21.7
|
1.0
|
|
C
|
C:ARG11
|
3.4
|
22.5
|
1.0
|
|
C
|
C:VAL14
|
3.5
|
22.1
|
1.0
|
|
C
|
C:GLN9
|
3.5
|
20.0
|
1.0
|
|
CG2
|
C:THR8
|
3.6
|
21.6
|
1.0
|
|
CB
|
C:THR8
|
3.6
|
20.8
|
1.0
|
|
N
|
C:GLN9
|
3.9
|
18.6
|
1.0
|
|
O
|
C:HOH245
|
3.9
|
24.9
|
1.0
|
|
O
|
C:GLY15
|
4.0
|
21.7
|
1.0
|
|
CG1
|
C:VAL14
|
4.0
|
25.1
|
1.0
|
|
N
|
C:ARG11
|
4.1
|
21.4
|
1.0
|
|
O
|
C:HOH207
|
4.2
|
33.6
|
1.0
|
|
N
|
C:VAL14
|
4.3
|
23.6
|
1.0
|
|
C
|
C:GLY15
|
4.3
|
21.6
|
1.0
|
|
C
|
C:ILE10
|
4.3
|
21.8
|
1.0
|
|
N
|
C:MET12
|
4.3
|
22.0
|
1.0
|
|
CA
|
C:MET12
|
4.3
|
22.9
|
1.0
|
|
CA
|
C:ARG11
|
4.3
|
21.7
|
1.0
|
|
CA
|
C:GLN9
|
4.3
|
18.8
|
1.0
|
|
CA
|
C:VAL14
|
4.4
|
23.3
|
1.0
|
|
N
|
C:GLY15
|
4.4
|
21.0
|
1.0
|
|
C
|
C:THR8
|
4.4
|
19.4
|
1.0
|
|
CA
|
C:GLY15
|
4.4
|
21.2
|
1.0
|
|
N
|
C:ILE10
|
4.5
|
20.6
|
1.0
|
|
O
|
C:PRO16
|
4.5
|
21.0
|
1.0
|
|
CA
|
C:THR8
|
4.5
|
19.0
|
1.0
|
|
CA
|
C:ILE10
|
4.5
|
21.7
|
1.0
|
|
C
|
C:MET12
|
4.6
|
22.7
|
1.0
|
|
O
|
C:ILE10
|
4.6
|
21.5
|
1.0
|
|
O
|
C:MET12
|
4.8
|
23.1
|
1.0
|
|
CB
|
C:VAL14
|
4.8
|
25.1
|
1.0
|
|
Potassium binding site 4 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 4 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 4 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:K101
b:15.2
occ:0.51
|
O
|
D:GLN9
|
2.2
|
20.8
|
1.0
|
|
O
|
D:HOH226
|
2.3
|
21.3
|
1.0
|
|
O
|
D:ARG11
|
2.3
|
19.7
|
1.0
|
|
O
|
D:VAL14
|
2.4
|
18.7
|
1.0
|
|
OG1
|
D:THR8
|
2.4
|
20.1
|
1.0
|
|
C
|
D:ARG11
|
3.4
|
20.1
|
1.0
|
|
CG2
|
D:THR8
|
3.5
|
20.7
|
1.0
|
|
C
|
D:GLN9
|
3.5
|
20.9
|
1.0
|
|
CB
|
D:THR8
|
3.5
|
20.5
|
1.0
|
|
C
|
D:VAL14
|
3.5
|
20.1
|
1.0
|
|
N
|
D:GLN9
|
3.8
|
19.7
|
1.0
|
|
O
|
D:HOH243
|
3.9
|
32.2
|
1.0
|
|
N
|
D:ARG11
|
4.0
|
21.2
|
1.0
|
|
CG1
|
D:VAL14
|
4.1
|
22.7
|
1.0
|
|
O
|
D:GLY15
|
4.1
|
20.2
|
1.0
|
|
C
|
D:ILE10
|
4.2
|
21.6
|
1.0
|
|
N
|
D:MET12
|
4.3
|
20.2
|
1.0
|
|
N
|
D:VAL14
|
4.3
|
21.3
|
1.0
|
|
CA
|
D:ARG11
|
4.3
|
21.0
|
1.0
|
|
CA
|
D:GLN9
|
4.3
|
19.8
|
1.0
|
|
C
|
D:THR8
|
4.3
|
20.3
|
1.0
|
|
CA
|
D:MET12
|
4.3
|
20.5
|
1.0
|
|
O
|
D:HOH241
|
4.4
|
33.5
|
1.0
|
|
C
|
D:GLY15
|
4.4
|
20.7
|
1.0
|
|
CA
|
D:VAL14
|
4.4
|
20.8
|
1.0
|
|
CA
|
D:THR8
|
4.4
|
19.8
|
1.0
|
|
N
|
D:GLY15
|
4.4
|
19.5
|
1.0
|
|
N
|
D:ILE10
|
4.5
|
20.9
|
1.0
|
|
CA
|
D:GLY15
|
4.5
|
19.4
|
1.0
|
|
CA
|
D:ILE10
|
4.5
|
22.4
|
1.0
|
|
O
|
D:PRO16
|
4.5
|
22.1
|
1.0
|
|
C
|
D:MET12
|
4.6
|
20.2
|
1.0
|
|
O
|
D:ILE10
|
4.6
|
20.7
|
1.0
|
|
O
|
D:MET12
|
4.9
|
19.8
|
1.0
|
|
CB
|
D:VAL14
|
4.9
|
22.0
|
1.0
|
|
Potassium binding site 5 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 5 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 5 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:K101
b:21.1
occ:0.51
|
O
|
E:GLN9
|
2.2
|
24.0
|
1.0
|
|
O
|
E:ARG11
|
2.3
|
22.8
|
1.0
|
|
O
|
E:VAL14
|
2.3
|
24.8
|
1.0
|
|
O
|
E:HOH216
|
2.4
|
27.0
|
1.0
|
|
OG1
|
E:THR8
|
2.5
|
22.1
|
1.0
|
|
C
|
E:ARG11
|
3.4
|
22.6
|
1.0
|
|
C
|
E:GLN9
|
3.5
|
23.7
|
1.0
|
|
C
|
E:VAL14
|
3.5
|
25.1
|
1.0
|
|
CG2
|
E:THR8
|
3.5
|
21.6
|
1.0
|
|
CB
|
E:THR8
|
3.6
|
22.1
|
1.0
|
|
N
|
E:GLN9
|
3.8
|
21.8
|
1.0
|
|
O
|
E:HOH243
|
4.0
|
25.6
|
1.0
|
|
O
|
E:GLY15
|
4.1
|
25.6
|
1.0
|
|
N
|
E:ARG11
|
4.1
|
23.0
|
1.0
|
|
CG1
|
E:VAL14
|
4.1
|
25.8
|
1.0
|
|
N
|
E:MET12
|
4.3
|
22.6
|
1.0
|
|
O
|
E:HOH217
|
4.3
|
31.4
|
1.0
|
|
C
|
E:ILE10
|
4.3
|
23.9
|
1.0
|
|
N
|
E:VAL14
|
4.3
|
24.8
|
1.0
|
|
CA
|
E:GLN9
|
4.3
|
22.6
|
1.0
|
|
CA
|
E:MET12
|
4.3
|
23.5
|
1.0
|
|
CA
|
E:ARG11
|
4.3
|
22.4
|
1.0
|
|
C
|
E:THR8
|
4.3
|
22.4
|
1.0
|
|
C
|
E:GLY15
|
4.3
|
25.1
|
1.0
|
|
CA
|
E:VAL14
|
4.4
|
24.9
|
1.0
|
|
N
|
E:GLY15
|
4.4
|
24.7
|
1.0
|
|
CA
|
E:THR8
|
4.4
|
21.9
|
1.0
|
|
N
|
E:ILE10
|
4.4
|
23.8
|
1.0
|
|
CA
|
E:GLY15
|
4.5
|
24.9
|
1.0
|
|
O
|
E:PRO16
|
4.5
|
24.7
|
1.0
|
|
CA
|
E:ILE10
|
4.5
|
24.9
|
1.0
|
|
C
|
E:MET12
|
4.5
|
24.0
|
1.0
|
|
O
|
E:ILE10
|
4.6
|
23.4
|
1.0
|
|
O
|
E:MET12
|
4.8
|
24.5
|
1.0
|
|
CB
|
E:VAL14
|
4.9
|
25.9
|
1.0
|
|
Potassium binding site 6 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 6 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 6 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:K101
b:15.5
occ:0.50
|
O
|
F:ARG11
|
2.2
|
20.4
|
1.0
|
|
O
|
F:GLN9
|
2.2
|
19.3
|
1.0
|
|
O
|
F:HOH241
|
2.3
|
23.7
|
1.0
|
|
O
|
F:VAL14
|
2.4
|
21.5
|
1.0
|
|
OG1
|
F:THR8
|
2.5
|
21.5
|
1.0
|
|
C
|
F:ARG11
|
3.3
|
20.3
|
1.0
|
|
C
|
F:GLN9
|
3.5
|
20.1
|
1.0
|
|
CG2
|
F:THR8
|
3.5
|
20.7
|
1.0
|
|
C
|
F:VAL14
|
3.5
|
22.1
|
1.0
|
|
CB
|
F:THR8
|
3.6
|
20.6
|
1.0
|
|
N
|
F:GLN9
|
3.9
|
18.7
|
1.0
|
|
O
|
F:HOH246
|
3.9
|
26.3
|
1.0
|
|
N
|
F:ARG11
|
4.0
|
19.9
|
1.0
|
|
CG1
|
F:VAL14
|
4.0
|
25.1
|
1.0
|
|
O
|
F:GLY15
|
4.1
|
22.8
|
1.0
|
|
O
|
F:HOH234
|
4.2
|
29.4
|
1.0
|
|
N
|
F:MET12
|
4.2
|
20.3
|
1.0
|
|
C
|
F:ILE10
|
4.2
|
20.8
|
1.0
|
|
CA
|
F:ARG11
|
4.2
|
19.9
|
1.0
|
|
N
|
F:VAL14
|
4.3
|
22.0
|
1.0
|
|
CA
|
F:MET12
|
4.3
|
21.2
|
1.0
|
|
CA
|
F:GLN9
|
4.3
|
19.6
|
1.0
|
|
C
|
F:THR8
|
4.3
|
18.8
|
1.0
|
|
CA
|
F:VAL14
|
4.4
|
22.6
|
1.0
|
|
C
|
F:GLY15
|
4.4
|
21.6
|
1.0
|
|
N
|
F:ILE10
|
4.4
|
20.5
|
1.0
|
|
N
|
F:GLY15
|
4.5
|
21.2
|
1.0
|
|
CA
|
F:THR8
|
4.5
|
18.6
|
1.0
|
|
CA
|
F:ILE10
|
4.5
|
21.9
|
1.0
|
|
C
|
F:MET12
|
4.5
|
21.9
|
1.0
|
|
CA
|
F:GLY15
|
4.6
|
20.7
|
1.0
|
|
O
|
F:ILE10
|
4.6
|
20.3
|
1.0
|
|
O
|
F:PRO16
|
4.6
|
22.1
|
1.0
|
|
O
|
F:MET12
|
4.8
|
23.5
|
1.0
|
|
CB
|
F:VAL14
|
4.9
|
24.7
|
1.0
|
|
Potassium binding site 7 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 7 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 7 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:K101
b:16.2
occ:0.49
|
O
|
G:GLN9
|
2.3
|
22.4
|
1.0
|
|
O
|
G:HOH232
|
2.3
|
22.5
|
1.0
|
|
O
|
G:ARG11
|
2.3
|
20.8
|
1.0
|
|
O
|
G:VAL14
|
2.4
|
22.8
|
1.0
|
|
OG1
|
G:THR8
|
2.5
|
21.1
|
1.0
|
|
C
|
G:ARG11
|
3.4
|
20.6
|
1.0
|
|
CG2
|
G:THR8
|
3.4
|
20.1
|
1.0
|
|
C
|
G:GLN9
|
3.5
|
21.4
|
1.0
|
|
CB
|
G:THR8
|
3.5
|
20.3
|
1.0
|
|
C
|
G:VAL14
|
3.5
|
23.6
|
1.0
|
|
N
|
G:GLN9
|
3.9
|
18.7
|
1.0
|
|
O
|
G:HOH237
|
3.9
|
24.6
|
1.0
|
|
CG1
|
G:VAL14
|
4.1
|
25.2
|
1.0
|
|
O
|
G:GLY15
|
4.1
|
23.4
|
1.0
|
|
N
|
G:ARG11
|
4.1
|
21.2
|
1.0
|
|
N
|
G:MET12
|
4.3
|
20.1
|
1.0
|
|
N
|
G:VAL14
|
4.3
|
24.2
|
1.0
|
|
CA
|
G:MET12
|
4.3
|
21.3
|
1.0
|
|
C
|
G:ILE10
|
4.3
|
21.7
|
1.0
|
|
CA
|
G:GLN9
|
4.3
|
20.0
|
1.0
|
|
C
|
G:THR8
|
4.3
|
19.0
|
1.0
|
|
CA
|
G:ARG11
|
4.3
|
21.3
|
1.0
|
|
CA
|
G:VAL14
|
4.4
|
24.4
|
1.0
|
|
C
|
G:GLY15
|
4.4
|
23.3
|
1.0
|
|
CA
|
G:THR8
|
4.4
|
18.8
|
1.0
|
|
N
|
G:ILE10
|
4.4
|
21.6
|
1.0
|
|
N
|
G:GLY15
|
4.5
|
23.3
|
1.0
|
|
CA
|
G:ILE10
|
4.5
|
22.6
|
1.0
|
|
C
|
G:MET12
|
4.5
|
22.2
|
1.0
|
|
O
|
G:PRO16
|
4.5
|
23.2
|
1.0
|
|
CA
|
G:GLY15
|
4.6
|
22.7
|
1.0
|
|
O
|
G:ILE10
|
4.7
|
20.9
|
1.0
|
|
O
|
G:MET12
|
4.8
|
22.6
|
1.0
|
|
CB
|
G:VAL14
|
4.9
|
25.5
|
1.0
|
|
Potassium binding site 8 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 8 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 8 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:K101
b:22.3
occ:0.58
|
O
|
H:GLN9
|
2.2
|
21.7
|
1.0
|
|
O
|
H:ARG11
|
2.3
|
22.1
|
1.0
|
|
O
|
H:VAL14
|
2.4
|
24.0
|
1.0
|
|
OG1
|
H:THR8
|
2.4
|
22.7
|
1.0
|
|
O
|
H:HOH240
|
2.4
|
25.3
|
1.0
|
|
C
|
H:GLN9
|
3.4
|
21.3
|
1.0
|
|
C
|
H:ARG11
|
3.4
|
21.9
|
1.0
|
|
CB
|
H:THR8
|
3.5
|
21.9
|
1.0
|
|
CG2
|
H:THR8
|
3.5
|
20.7
|
1.0
|
|
C
|
H:VAL14
|
3.6
|
24.4
|
1.0
|
|
N
|
H:GLN9
|
3.8
|
20.2
|
1.0
|
|
O
|
H:HOH248
|
3.9
|
27.0
|
1.0
|
|
O
|
H:GLY15
|
4.1
|
26.2
|
1.0
|
|
N
|
H:ARG11
|
4.1
|
21.8
|
1.0
|
|
CG1
|
H:VAL14
|
4.2
|
26.7
|
1.0
|
|
CA
|
H:GLN9
|
4.2
|
20.4
|
1.0
|
|
O
|
H:HOH219
|
4.2
|
41.6
|
1.0
|
|
N
|
H:MET12
|
4.3
|
21.1
|
1.0
|
|
C
|
H:THR8
|
4.3
|
21.1
|
1.0
|
|
CA
|
H:MET12
|
4.3
|
21.1
|
1.0
|
|
C
|
H:ILE10
|
4.3
|
21.8
|
1.0
|
|
N
|
H:VAL14
|
4.3
|
24.6
|
1.0
|
|
C
|
H:GLY15
|
4.4
|
25.1
|
1.0
|
|
CA
|
H:ARG11
|
4.4
|
22.2
|
1.0
|
|
CA
|
H:THR8
|
4.4
|
20.8
|
1.0
|
|
N
|
H:ILE10
|
4.4
|
21.1
|
1.0
|
|
CA
|
H:VAL14
|
4.4
|
25.1
|
1.0
|
|
O
|
H:PRO16
|
4.5
|
22.0
|
1.0
|
|
N
|
H:GLY15
|
4.5
|
24.3
|
1.0
|
|
CA
|
H:GLY15
|
4.5
|
24.8
|
1.0
|
|
C
|
H:MET12
|
4.5
|
21.2
|
1.0
|
|
CA
|
H:ILE10
|
4.5
|
22.0
|
1.0
|
|
O
|
H:ILE10
|
4.7
|
21.2
|
1.0
|
|
O
|
H:MET12
|
4.8
|
20.8
|
1.0
|
|
CB
|
H:VAL14
|
5.0
|
26.4
|
1.0
|
|
Potassium binding site 9 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 9 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 9 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:K101
b:18.9
occ:0.43
|
O
|
I:GLN9
|
2.3
|
22.1
|
1.0
|
|
O
|
I:VAL14
|
2.3
|
23.5
|
1.0
|
|
O
|
I:ARG11
|
2.3
|
24.0
|
1.0
|
|
O
|
I:HOH222
|
2.3
|
26.3
|
1.0
|
|
OG1
|
I:THR8
|
2.5
|
24.0
|
1.0
|
|
C
|
I:ARG11
|
3.4
|
23.6
|
1.0
|
|
C
|
I:VAL14
|
3.5
|
24.6
|
1.0
|
|
C
|
I:GLN9
|
3.5
|
21.9
|
1.0
|
|
CG2
|
I:THR8
|
3.5
|
21.8
|
1.0
|
|
CB
|
I:THR8
|
3.6
|
22.6
|
1.0
|
|
N
|
I:GLN9
|
3.9
|
20.9
|
1.0
|
|
O
|
I:HOH236
|
4.0
|
28.2
|
1.0
|
|
CG1
|
I:VAL14
|
4.0
|
26.2
|
1.0
|
|
O
|
I:GLY15
|
4.1
|
28.3
|
1.0
|
|
N
|
I:ARG11
|
4.1
|
23.0
|
1.0
|
|
N
|
I:VAL14
|
4.2
|
23.6
|
1.0
|
|
O
|
I:HOH204
|
4.3
|
38.3
|
1.0
|
|
N
|
I:MET12
|
4.3
|
22.7
|
1.0
|
|
C
|
I:ILE10
|
4.3
|
23.3
|
1.0
|
|
CA
|
I:MET12
|
4.3
|
22.3
|
1.0
|
|
CA
|
I:GLN9
|
4.3
|
21.2
|
1.0
|
|
C
|
I:GLY15
|
4.3
|
27.9
|
1.0
|
|
CA
|
I:VAL14
|
4.3
|
24.5
|
1.0
|
|
CA
|
I:ARG11
|
4.3
|
23.5
|
1.0
|
|
C
|
I:THR8
|
4.4
|
21.8
|
1.0
|
|
N
|
I:GLY15
|
4.4
|
24.8
|
1.0
|
|
CA
|
I:GLY15
|
4.5
|
26.3
|
1.0
|
|
CA
|
I:THR8
|
4.5
|
21.6
|
1.0
|
|
N
|
I:ILE10
|
4.5
|
22.3
|
1.0
|
|
O
|
I:PRO16
|
4.5
|
25.6
|
1.0
|
|
C
|
I:MET12
|
4.5
|
21.6
|
1.0
|
|
CA
|
I:ILE10
|
4.5
|
23.7
|
1.0
|
|
O
|
I:ILE10
|
4.7
|
22.9
|
1.0
|
|
O
|
I:MET12
|
4.8
|
22.2
|
1.0
|
|
CB
|
I:VAL14
|
4.8
|
25.9
|
1.0
|
|
Potassium binding site 10 out
of 10 in 7acc
Go back to
Potassium Binding Sites List in 7acc
Potassium binding site 10 out
of 10 in the Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp)
 Mono view
 Stereo pair view
|
|
A full contact list of Potassium with other atoms in the K binding
site number 10 of Human Gtp Cyclohydrolase I Feedback Regulatory Protein (Gfrp) within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:K101
b:15.9
occ:0.48
|
O
|
J:VAL14
|
2.3
|
24.1
|
1.0
|
|
O
|
J:ARG11
|
2.3
|
21.5
|
1.0
|
|
O
|
J:GLN9
|
2.3
|
20.2
|
1.0
|
|
O
|
J:HOH222
|
2.4
|
23.9
|
1.0
|
|
OG1
|
J:THR8
|
2.5
|
21.4
|
1.0
|
|
C
|
J:ARG11
|
3.4
|
21.7
|
1.0
|
|
C
|
J:VAL14
|
3.5
|
24.6
|
1.0
|
|
CG2
|
J:THR8
|
3.5
|
19.7
|
1.0
|
|
C
|
J:GLN9
|
3.5
|
20.3
|
1.0
|
|
CB
|
J:THR8
|
3.6
|
20.5
|
1.0
|
|
N
|
J:GLN9
|
3.9
|
18.9
|
1.0
|
|
O
|
J:HOH240
|
3.9
|
23.9
|
1.0
|
|
CG1
|
J:VAL14
|
4.0
|
26.0
|
1.0
|
|
O
|
J:GLY15
|
4.0
|
24.6
|
1.0
|
|
N
|
J:ARG11
|
4.1
|
21.9
|
1.0
|
|
N
|
J:VAL14
|
4.2
|
23.6
|
1.0
|
|
O
|
J:HOH234
|
4.3
|
43.3
|
1.0
|
|
N
|
J:MET12
|
4.3
|
21.2
|
1.0
|
|
C
|
J:ILE10
|
4.3
|
22.8
|
1.0
|
|
CA
|
J:ARG11
|
4.3
|
21.9
|
1.0
|
|
CA
|
J:VAL14
|
4.3
|
24.3
|
1.0
|
|
CA
|
J:MET12
|
4.3
|
21.7
|
1.0
|
|
C
|
J:GLY15
|
4.4
|
24.8
|
1.0
|
|
C
|
J:THR8
|
4.4
|
19.8
|
1.0
|
|
CA
|
J:GLN9
|
4.4
|
19.3
|
1.0
|
|
N
|
J:GLY15
|
4.4
|
24.5
|
1.0
|
|
CA
|
J:THR8
|
4.5
|
19.4
|
1.0
|
|
CA
|
J:GLY15
|
4.5
|
24.5
|
1.0
|
|
N
|
J:ILE10
|
4.5
|
20.5
|
1.0
|
|
C
|
J:MET12
|
4.6
|
22.6
|
1.0
|
|
O
|
J:PRO16
|
4.6
|
22.2
|
1.0
|
|
CA
|
J:ILE10
|
4.6
|
22.9
|
1.0
|
|
O
|
J:ILE10
|
4.7
|
22.3
|
1.0
|
|
CB
|
J:VAL14
|
4.8
|
25.8
|
1.0
|
|
O
|
J:MET12
|
4.8
|
22.7
|
1.0
|
|
Reference:
R.Ebenhoch,
S.Prinz,
S.Kaltwasser,
D.J.Mills,
R.Meinecke,
M.Rubbelke,
D.Reinert,
M.Bauer,
L.Weixler,
M.Zeeb,
J.Vonck,
H.Nar.
A Hybrid Approach Reveals the Allosteric Regulation of Gtp Cyclohydrolase I. Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
PubMed: 33229582
DOI: 10.1073/PNAS.2013473117
Page generated: Mon Aug 12 18:36:10 2024
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