Potassium in PDB 6zw1: X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101

The structure of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101, PDB code: 6zw1 was solved by C.Barinka, L.Motlova, K.Ustinova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.08 / 1.13
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	83.933, 94.158, 51.487, 90, 90, 90
R / Rfree (%)	14 / 15.9

The structure of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Potassium atom in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 (pdb code 6zw1). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101, PDB code: 6zw1:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 within 5.0Å range: probe atom residue distance (Å) B Occ A:K2005 b:8.7 occ:1.00 O A:ASP612 2.5 8.1 1.0 O A:LEU634 2.7 8.0 1.0 O A:HIS614 2.7 8.5 1.0 OG A:SER633 2.7 8.8 1.0 OD1 A:ASP610 2.7 8.5 1.0 O A:ASP610 2.8 8.0 1.0 CG A:ASP610 3.2 7.6 1.0 C A:ASP610 3.5 7.2 1.0 C A:ASP612 3.6 7.9 1.0 C A:HIS614 3.6 8.2 1.0 C A:LEU634 3.7 7.1 1.0 CB A:ASP610 3.8 7.3 1.0 N A:ASP612 3.9 7.5 1.0 CB A:SER633 3.9 7.9 1.0 N A:LEU634 3.9 7.3 1.0 OD2 A:ASP610 3.9 8.5 1.0 CB A:HIS635 4.0 7.8 1.0 CA A:ASP612 4.2 7.1 1.0 N A:TRP611 4.2 6.9 1.0 C A:TRP611 4.2 7.4 1.0 CA A:ASP610 4.2 7.7 1.0 CB A:ASP612 4.3 6.9 1.0 CA A:SER633 4.3 7.3 1.0 ND1 A:HIS635 4.3 8.3 1.0 CA A:HIS615 4.3 7.9 1.0 N A:HIS615 4.4 7.7 1.0 CA A:TRP611 4.4 6.9 1.0 N A:HIS614 4.4 7.7 1.0 CA A:HIS635 4.5 7.1 1.0 C A:SER633 4.5 7.6 1.0 CA A:LEU634 4.5 7.1 1.0 O A:HOH2144 4.5 9.2 1.0 N A:GLY616 4.5 7.8 1.0 N A:HIS635 4.5 7.6 1.0 CG A:HIS635 4.6 8.2 1.0 C A:VAL613 4.6 8.2 1.0 CA A:HIS614 4.6 7.7 1.0 N A:VAL613 4.7 7.8 1.0 OH A:TYR631 4.7 8.3 1.0 CE1 A:HIS573 4.8 8.6 1.0 C A:HIS615 4.8 8.1 1.0 ND1 A:HIS573 4.9 8.4 1.0 O A:TRP611 4.9 7.8 1.0

Potassium binding site 2 out of 2 in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 within 5.0Å range: probe atom residue distance (Å) B Occ A:K2006 b:9.0 occ:1.00 O A:VAL629 2.7 9.7 1.0 O A:PHE623 2.7 9.4 1.0 O A:HOH2206 2.7 10.0 1.0 O A:TYR662 2.8 8.6 1.0 O A:HOH2250 2.9 8.9 1.0 O A:ASP626 2.9 11.9 1.0 C A:TYR662 3.6 8.3 1.0 C A:PHE623 3.6 9.8 1.0 CB A:TYR662 3.7 8.6 1.0 CB A:PHE623 3.7 8.5 1.0 C A:VAL629 3.9 8.6 1.0 C A:ASP626 4.1 10.5 1.0 CA A:TYR662 4.2 9.2 1.0 CA A:PHE623 4.3 8.8 1.0 N A:TYR631 4.3 7.5 1.0 N A:ASN663 4.4 8.2 1.0 N A:ASP626 4.4 12.1 1.0 CB A:ASP626 4.4 13.7 1.0 N A:GLU624 4.5 9.3 1.0 CA A:ASP626 4.6 10.7 1.0 CA A:GLU624 4.6 9.5 1.0 CA A:LEU630 4.6 8.0 1.0 N A:LEU630 4.7 8.0 1.0 C A:GLU624 4.7 9.6 1.0 O A:GLU624 4.7 10.5 1.0 CA A:ASN663 4.7 7.8 1.0 CB A:TYR631 4.8 7.8 1.0 CB A:ASN663 4.8 8.0 1.0 O A:GLY659 4.9 11.2 1.0 C A:LEU630 4.9 8.4 1.0 CA A:VAL629 4.9 8.7 1.0 OD1 A:ASN663 5.0 8.5 1.0 CG A:PHE623 5.0 8.5 1.0 CG A:TYR662 5.0 9.3 1.0

C.Barinka, L.Motlova, K.Ustinova. X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 To Be Published.