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Potassium in PDB 6yaa: Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
Enzymatic activity of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
All present enzymatic activity of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp:
7.2.2.10;
7.2.2.10;
Protein crystallography data
The structure of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp, PDB code: 6yaa
was solved by
S.Heit,
M.Marchesini,
A.Gherli,
A.Montanaro,
L.Patrizi,
C.Sorrentino,
L.Pagliaro,
C.Rompietti,
S.Kitara,
C.E.Olesen,
J.V.Moller,
M.Savi,
L.Bocchi,
R.Vilella,
F.Rizzi,
M.Baglione,
G.Rastelli,
C.Loiacona,
R.Lastarza,
C.Mecucci,
K.Stegmair,
F.Aversa,
D.Stilli,
A.M.Lund Winther,
P.Sportoletti,
W.Dalby-Brown,
G.Roti,
M.Bublitz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 57.84 / 3.40 |
| Space group | P 41 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 71.632, 71.632, 588.306, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 22.8 / 25.5 |
Other elements in 6yaa:
The structure of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp also contains other interesting chemical elements:
| Fluorine | (F) | 3 atoms |
Potassium Binding Sites:
The binding sites of Potassium atom in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
(pdb code 6yaa). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp, PDB code: 6yaa:
In total only one binding site of Potassium was determined in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp, PDB code: 6yaa:
Potassium binding site 1 out of 1 in 6yaa
Go back to
Potassium Binding Sites List in 6yaa
Potassium binding site 1 out
of 1 in the Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of Structure of the (Sr) CA2+-Atpase Bound to the Inhibitor Compound CAD204520 and Tnp-Atp within 5.0Å range:
|
Reference:
M.Marchesini,
A.Gherli,
A.Montanaro,
L.Patrizi,
C.Sorrentino,
L.Pagliaro,
C.Rompietti,
S.Kitara,
S.Heit,
C.E.Olesen,
J.V.Moller,
M.Savi,
L.Bocchi,
R.Vilella,
F.Rizzi,
M.Baglione,
G.Rastelli,
C.Loiacono,
R.La Starza,
C.Mecucci,
K.Stegmaier,
F.Aversa,
D.Stilli,
A.M.Lund Winther,
P.Sportoletti,
M.Bublitz,
W.Dalby-Brown,
G.Roti.
Blockade of Oncogenic NOTCH1 with the Serca Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol 2020.
ISSN: ESSN 2451-9456
PubMed: 32386594
DOI: 10.1016/J.CHEMBIOL.2020.04.002
Page generated: Sat Aug 9 12:47:16 2025
ISSN: ESSN 2451-9456
PubMed: 32386594
DOI: 10.1016/J.CHEMBIOL.2020.04.002
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