Potassium in PDB 6xoc: Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab

The structure of Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab, PDB code: 6xoc was solved by S.S.Aljedani, C.Weidle, M.Pancera, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 2.45
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	100.016, 114.417, 220.969, 90, 90, 90
R / Rfree (%)	19.9 / 24

The binding sites of Potassium atom in the Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab (pdb code 6xoc). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab, PDB code: 6xoc:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:K301 b:71.4 occ:1.00 O A:VAL2 3.8 41.7 1.0 CG2 A:VAL2 3.8 41.7 1.0 OE1 A:GLN5 3.9 61.9 1.0 O A:LYS23 3.9 29.8 1.0 CB A:GLN5 4.0 35.1 1.0 O A:HOH477 4.1 41.7 1.0 CB A:LYS23 4.3 34.2 1.0 C A:LYS23 4.4 34.0 1.0 CE A:LYS23 4.5 83.9 1.0 C A:VAL2 4.7 44.9 1.0 CD A:GLN5 4.7 43.1 1.0 N A:GLN5 4.7 28.6 1.0 C A:ALA24 4.7 32.4 1.0 N A:SER25 4.8 24.6 1.0 N A:ALA24 4.9 29.3 1.0 C A:LEU4 4.9 33.2 1.0 O A:ALA24 4.9 31.9 1.0 CG A:GLN5 4.9 36.7 1.0 CA A:ALA24 5.0 29.7 1.0

Potassium binding site 2 out of 3 in the Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:K302 b:90.1 occ:1.00 OG A:SER75 3.2 33.0 1.0 OH A:TYR79 3.4 33.7 1.0 OD2 A:ASP72 3.6 37.3 1.0 CB A:SER75 3.7 28.6 1.0 CG A:ASP72 3.9 36.9 1.0 CB A:ASP72 4.4 32.6 1.0 OD1 A:ASP72 4.5 38.9 1.0 O A:HOH405 4.5 38.8 1.0 CZ A:TYR79 4.6 29.9 1.0 CE2 A:TYR79 4.9 38.6 1.0

Potassium binding site 3 out of 3 in the Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of GLVRC01 Fab in Complex with Anti-Idiotypic IV4 Fab within 5.0Å range: probe atom residue distance (Å) B Occ A:K303 b:56.6 occ:1.00 O A:HOH454 2.7 41.8 1.0 C A:GLN6 3.6 26.3 1.0 N A:PRO7 3.6 26.9 1.0 CG A:GLN5 3.8 36.7 1.0 CD A:PRO7 3.8 31.0 1.0 O A:GLN5 3.9 29.8 1.0 OE1 A:GLN5 3.9 61.9 1.0 CD A:GLN5 3.9 43.1 1.0 C A:GLN5 3.9 29.8 1.0 N A:GLN6 4.0 26.7 1.0 CA A:GLN6 4.0 28.9 1.0 O A:GLN6 4.0 32.5 1.0 CG A:PRO7 4.1 30.7 1.0 CB A:GLN5 4.2 35.1 1.0 CA A:PRO7 4.3 26.5 1.0 CD A:LYS23 4.3 81.9 1.0 NE2 A:GLN5 4.7 70.7 1.0 CA A:GLN5 4.7 34.4 1.0 CB A:PRO7 4.7 22.3 1.0 CB A:LYS23 4.8 34.2 1.0 CG A:LYS23 4.8 52.8 1.0

E.Seydoux, Y.Wan, J.Feng, A.Wall, S.S.Aljedani, L.Homad, A.Maccamy, C.Weidle, L.Brumage, M.Gary, J.Tyler, M.Pancera, L.Stamatatos, A.Mcguire. Development of A Novel VRC01-Class Germline Targeting Immunogen Derived From Anti-Idiotypic Antibodies To Be Published.