Potassium in PDB 6xlf: Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp

The structure of Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Potassium atom in the Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp (pdb code 6xlf). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp, PDB code: 6xlf:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp within 5.0Å range: probe atom residue distance (Å) B Occ A:K803 b:43.1 occ:1.00 O A:GLY121 2.9 41.6 1.0 O A:ASN92 3.0 47.0 1.0 OH A:TYR125 3.0 36.0 1.0 O A:LYS98 3.1 41.3 1.0 O A:THR95 3.1 41.2 1.0 O2A A:ANP801 3.4 49.6 1.0 CZ A:TYR125 3.7 36.0 1.0 C5' A:ANP801 3.7 49.6 1.0 CE2 A:TYR125 3.8 36.0 1.0 C A:GLY121 4.0 41.6 1.0 C A:ASN92 4.0 47.0 1.0 C A:LYS98 4.1 41.3 1.0 C A:THR95 4.2 41.2 1.0 N A:LYS98 4.3 41.3 1.0 CA A:GLY121 4.6 41.6 1.0 PA A:ANP801 4.6 49.6 1.0 CA A:LEU93 4.6 44.3 1.0 CA A:LYS98 4.6 41.3 1.0 O5' A:ANP801 4.6 49.6 1.0 CB A:LYS98 4.7 41.3 1.0 N A:LEU93 4.7 44.3 1.0 N A:ALA97 4.7 39.4 1.0 N A:THR95 4.8 41.2 1.0 CE1 A:TYR125 4.8 36.0 1.0 C4' A:ANP801 4.9 49.6 1.0 C A:LEU93 5.0 44.3 1.0 CA A:ILE96 5.0 40.2 1.0

Potassium binding site 2 out of 2 in the Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Full-Length HSC82 in Complex with AHA1 in the Presence of Amp-Pnp within 5.0Å range: probe atom residue distance (Å) B Occ B:K803 b:45.2 occ:1.00 O B:ASN92 2.9 47.9 1.0 O B:GLY121 2.9 36.5 1.0 O B:THR95 3.0 41.5 1.0 O B:LYS98 3.2 41.4 1.0 O2A B:ANP801 3.3 29.6 1.0 C5' B:ANP801 3.6 29.6 1.0 OH B:TYR125 3.6 34.3 1.0 CE2 B:TYR125 3.8 34.3 1.0 C B:GLY121 4.0 36.5 1.0 CZ B:TYR125 4.1 34.3 1.0 C B:ASN92 4.1 47.9 1.0 C B:THR95 4.1 41.5 1.0 C B:LYS98 4.2 41.4 1.0 N B:LYS98 4.3 41.4 1.0 O B:LEU93 4.3 43.0 1.0 CA B:LEU93 4.3 43.0 1.0 C B:LEU93 4.5 43.0 1.0 PA B:ANP801 4.5 29.6 1.0 O5' B:ANP801 4.5 29.6 1.0 CA B:GLY121 4.5 36.5 1.0 N B:ALA97 4.6 37.5 1.0 CA B:ILE96 4.6 37.6 1.0 CA B:LYS98 4.7 41.4 1.0 N B:LEU93 4.7 43.0 1.0 C4' B:ANP801 4.7 29.6 1.0 CB B:LYS98 4.8 41.4 1.0 N B:ILE96 4.8 37.6 1.0 CD2 B:TYR125 4.8 34.3 1.0 C B:ILE96 4.9 37.6 1.0

Y.X.Liu, M.Sun, A.G.Myasnikov, D.Elnatan, D.A.Agard. Cryo-Em Structures Reveal A Multistep Mechanism of HSP90 Activation By Co-Chaperone AHA1 To Be Published.