Potassium in PDB 6w7c: K2P2.1 (Trek-1), 1 Mm K+

The structure of K2P2.1 (Trek-1), 1 Mm K+, PDB code: 6w7c was solved by M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.99 / 3.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	66.501, 123.014, 125.848, 90, 90, 90
R / Rfree (%)	28.2 / 28.9

The structure of K2P2.1 (Trek-1), 1 Mm K+ also contains other interesting chemical elements:

Cadmium

(Cd)

3 atoms

The binding sites of Potassium atom in the K2P2.1 (Trek-1), 1 Mm K+ (pdb code 6w7c). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the K2P2.1 (Trek-1), 1 Mm K+, PDB code: 6w7c:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the K2P2.1 (Trek-1), 1 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of K2P2.1 (Trek-1), 1 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K408 b:130.3 occ:1.00 O B:THR251 2.7 133.6 1.0 O A:THR251 2.8 125.9 1.0 OG1 B:THR251 2.9 141.3 1.0 OG1 A:THR251 2.9 128.2 1.0 O A:THR142 3.0 116.4 1.0 OG1 A:THR142 3.0 115.4 1.0 OG1 B:THR142 3.2 126.2 1.0 CG2 B:THR251 3.2 139.6 1.0 CB A:THR251 3.2 125.0 1.0 O B:THR142 3.2 119.8 1.0 CB A:THR142 3.4 114.0 1.0 CB B:THR251 3.6 138.3 1.0 CB B:THR142 3.7 125.4 1.0 C A:THR251 3.8 125.0 1.0 C B:THR251 3.8 132.5 1.0 K A:K410 3.9 122.7 1.0 C A:THR142 3.9 117.6 1.0 CA A:THR251 4.1 124.3 1.0 C B:THR142 4.2 122.2 1.0 CA A:THR142 4.3 115.0 1.0 CA B:THR251 4.4 134.8 1.0 CG2 A:THR251 4.4 125.2 1.0 CA B:THR142 4.6 122.3 1.0 CG2 A:THR142 4.6 111.5 1.0 CG2 B:THR142 4.8 127.6 1.0 O A:THR250 4.9 123.5 1.0 N A:ILE143 4.9 121.5 1.0 O A:THR141 4.9 114.1 1.0 N B:ILE252 4.9 129.8 1.0 K A:K409 5.0 176.1 1.0

Potassium binding site 2 out of 3 in the K2P2.1 (Trek-1), 1 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of K2P2.1 (Trek-1), 1 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K409 b:176.1 occ:1.00 OG1 A:THR142 4.3 115.4 1.0 CG2 B:THR251 4.4 139.6 1.0 K A:K408 5.0 130.3 1.0

Potassium binding site 3 out of 3 in the K2P2.1 (Trek-1), 1 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of K2P2.1 (Trek-1), 1 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K410 b:122.7 occ:1.00 O B:ILE143 2.8 135.2 1.0 O A:THR142 2.8 116.4 1.0 O A:ILE143 2.8 133.3 1.0 O B:THR142 2.8 119.8 1.0 O B:ILE252 2.9 132.6 1.0 O A:THR251 3.1 125.9 1.0 O B:THR251 3.3 133.6 1.0 C B:ILE252 3.6 132.3 1.0 O A:ILE252 3.6 136.0 1.0 C A:ILE143 3.6 135.5 1.0 C B:ILE143 3.7 135.3 1.0 C A:ILE252 3.8 139.8 1.0 K A:K408 3.9 130.3 1.0 C A:THR251 3.9 125.0 1.0 C A:THR142 4.0 117.6 1.0 C B:THR142 4.0 122.2 1.0 CA B:ILE252 4.1 129.5 1.0 CA A:ILE143 4.1 127.4 1.0 CA A:ILE252 4.2 130.9 1.0 N A:GLY253 4.2 150.8 1.0 C B:THR251 4.2 132.5 1.0 CA B:ILE143 4.2 125.7 1.0 N B:GLY253 4.4 134.7 1.0 N A:ILE252 4.4 126.6 1.0 O A:GLY144 4.5 171.8 1.0 CA A:GLY253 4.5 161.6 1.0 N A:ILE143 4.6 121.5 1.0 N B:ILE143 4.6 123.5 1.0 N B:ILE252 4.6 129.8 1.0 N A:GLY144 4.6 146.4 1.0 N B:GLY144 4.7 145.1 1.0 CA B:GLY253 4.7 136.2 1.0 OG1 B:THR251 4.7 141.3 1.0 CA B:GLY144 4.9 155.5 1.0 CA A:GLY144 4.9 160.7 1.0 C A:GLY144 5.0 180.0 1.0 CA A:THR251 5.0 124.3 1.0

M.Lolicato, A.M.Natale, F.Abderemane-Ali, D.Crottes, S.Capponi, R.Duman, A.Wagner, J.M.Rosenberg, M.Grabe, D.L.Minor Jr.. K 2P Channel C-Type Gating Involves Asymmetric Selectivity Filter Order-Disorder Transitions. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33127683
DOI: 10.1126/SCIADV.ABC9174