Potassium in PDB 6ugx: Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A

The structure of Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A, PDB code: 6ugx was solved by S.J.Mayclin, T.E.Edwards, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.400, 74.610, 149.090, 90.00, 90.00, 90.00
R / Rfree (%)	19.8 / 25.6

The structure of Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Potassium atom in the Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A (pdb code 6ugx). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A, PDB code: 6ugx:

Potassium binding site 1 out of 1 in the Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Fc Fragment of PF06438179/GP1111 An Infliximab Biosimilar in A Primative Orthorhombic Crystal Form, Lot A within 5.0Å range: probe atom residue distance (Å) B Occ B:K501 b:5.2 occ:1.00 O B:THR259 2.7 22.9 1.0 O B:HOH666 2.8 14.6 1.0 OD2 B:ASP252 2.9 22.5 1.0 O B:HOH633 3.3 17.3 1.0 OG1 B:THR259 3.5 43.1 1.0 CG B:ASP252 3.7 26.3 1.0 C B:THR259 3.8 37.2 1.0 O B:HOH635 4.1 16.3 1.0 OD1 B:ASP252 4.1 22.4 1.0 O B:HOH658 4.2 23.6 1.0 CB B:THR259 4.3 47.0 1.0 OE1 B:GLU261 4.4 39.3 1.0 CA B:THR259 4.4 37.3 1.0 CD B:GLU261 4.6 44.8 1.0 N B:THR259 4.6 38.4 1.0 N B:PRO260 4.8 31.1 1.0 CB B:ASP252 4.8 28.4 1.0 CG B:GLU261 4.9 44.0 1.0 CA B:PRO260 5.0 28.8 1.0 OE2 B:GLU261 5.0 49.6 1.0

T.F.Lerch, P.Sharpe, S.J.Mayclin, T.E.Edwards, S.Polleck, J.C.Rouse, Q.Zou, H.D.Conlon. Crystal Structures of Pf-06438179/GP1111, An Infliximab Biosimilar. Biodrugs 2019.
ISSN: ISSN 1179-190X
PubMed: 31650490
DOI: 10.1007/S40259-019-00390-1