Potassium in PDB 6u9z: Wild-Type Mthk Pore in 6 Mm K+

The structure of Wild-Type Mthk Pore in 6 Mm K+, PDB code: 6u9z was solved by D.J.Posson, C.M.Nimigean, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.05 / 1.95
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.811, 63.811, 44.050, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 22.6

The binding sites of Potassium atom in the Wild-Type Mthk Pore in 6 Mm K+ (pdb code 6u9z). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 5 binding sites of Potassium where determined in the Wild-Type Mthk Pore in 6 Mm K+, PDB code: 6u9z:
Jump to Potassium binding site number: 1; 2; 3; 4; 5;

Potassium binding site 1 out of 5 in the Wild-Type Mthk Pore in 6 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Wild-Type Mthk Pore in 6 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K101 b:17.0 occ:0.18 O A:GLY61 2.9 21.8 1.0 O A:TYR62 2.9 18.9 1.0 K A:K102 2.9 15.3 0.1 C A:TYR62 3.5 18.3 1.0 C A:GLY61 4.0 22.4 1.0 CA A:TYR62 4.0 18.9 1.0 N A:GLY63 4.3 20.5 1.0 N A:TYR62 4.5 18.3 1.0 CA A:GLY63 4.7 20.3 1.0 O A:HOH212 4.8 30.6 1.0

Potassium binding site 2 out of 5 in the Wild-Type Mthk Pore in 6 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Wild-Type Mthk Pore in 6 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K102 b:15.3 occ:0.08 K A:K103 2.7 17.7 0.2 O A:GLY61 2.9 21.8 1.0 K A:K101 2.9 17.0 0.2 O A:VAL60 2.9 19.4 1.0 C A:GLY61 3.6 22.4 1.0 C A:VAL60 4.0 19.0 1.0 CA A:GLY61 4.1 21.5 1.0 N A:TYR62 4.5 18.3 1.0 N A:GLY61 4.5 22.8 1.0 CA A:TYR62 4.8 18.9 1.0 O A:THR59 5.0 21.2 1.0

Potassium binding site 3 out of 5 in the Wild-Type Mthk Pore in 6 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Wild-Type Mthk Pore in 6 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K103 b:17.7 occ:0.22 K A:K102 2.7 15.3 0.1 O A:THR59 2.8 21.2 1.0 O A:VAL60 2.8 19.4 1.0 K A:K104 3.5 17.0 0.2 C A:VAL60 3.6 19.0 1.0 C A:THR59 4.0 20.8 1.0 CA A:VAL60 4.1 19.9 1.0 N A:GLY61 4.5 22.8 1.0 N A:VAL60 4.6 18.7 1.0 CA A:GLY61 4.7 21.5 1.0 O A:GLY61 4.8 21.8 1.0

Potassium binding site 4 out of 5 in the Wild-Type Mthk Pore in 6 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Wild-Type Mthk Pore in 6 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K104 b:17.0 occ:0.22 O A:THR59 2.8 21.2 1.0 OG1 A:THR59 2.9 21.7 1.0 CB A:THR59 3.4 20.5 1.0 K A:K103 3.5 17.7 0.2 C A:THR59 3.7 20.8 1.0 CA A:THR59 4.2 19.9 1.0 CG2 A:THR59 4.6 20.1 1.0 N A:VAL60 4.7 18.7 1.0 O A:ALA58 5.0 20.3 1.0

Potassium binding site 5 out of 5 in the Wild-Type Mthk Pore in 6 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Wild-Type Mthk Pore in 6 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K105 b:54.5 occ:0.18 O A:HOH230 3.1 54.3 1.0

C.Boiteux, D.J.Posson, T.W.Allen, C.M.Nimigean. Selectivity Filter Ion Binding Affinity Determines Inactivation in A Potassium Channel. Proc.Natl.Acad.Sci.Usa V. 117 29968 2020.
ISSN: ESSN 1091-6490
PubMed: 33154158
DOI: 10.1073/PNAS.2009624117