Potassium in PDB 6u9t: Wild-Type Mthk Pore in 50 Mm K+

The structure of Wild-Type Mthk Pore in 50 Mm K+, PDB code: 6u9t was solved by D.J.Posson, C.M.Nimigean, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.90 / 1.55
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.811, 63.811, 44.050, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 21

The binding sites of Potassium atom in the Wild-Type Mthk Pore in 50 Mm K+ (pdb code 6u9t). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 5 binding sites of Potassium where determined in the Wild-Type Mthk Pore in 50 Mm K+, PDB code: 6u9t:
Jump to Potassium binding site number: 1; 2; 3; 4; 5;

Potassium binding site 1 out of 5 in the Wild-Type Mthk Pore in 50 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Wild-Type Mthk Pore in 50 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K101 b:18.7 occ:0.20 O A:GLY61 2.8 16.9 1.0 O A:TYR62 2.9 16.6 1.0 K A:K102 3.0 19.6 0.1 C A:TYR62 3.4 16.1 1.0 C A:GLY61 3.9 16.9 1.0 CA A:TYR62 3.9 16.0 1.0 N A:GLY63 4.3 17.6 1.0 N A:TYR62 4.4 15.6 1.0 CA A:GLY63 4.7 18.1 1.0 O A:HOH211 4.8 29.9 1.0

Potassium binding site 2 out of 5 in the Wild-Type Mthk Pore in 50 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Wild-Type Mthk Pore in 50 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K102 b:19.6 occ:0.12 K A:K103 2.8 18.6 0.2 O A:GLY61 2.8 16.9 1.0 O A:VAL60 2.9 15.7 1.0 K A:K101 3.0 18.7 0.2 C A:GLY61 3.5 16.9 1.0 CA A:GLY61 4.0 16.7 1.0 C A:VAL60 4.0 15.5 1.0 N A:TYR62 4.4 15.6 1.0 N A:GLY61 4.5 17.4 1.0 CA A:TYR62 4.8 16.0 1.0

Potassium binding site 3 out of 5 in the Wild-Type Mthk Pore in 50 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Wild-Type Mthk Pore in 50 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K103 b:18.6 occ:0.24 O A:VAL60 2.7 15.7 1.0 K A:K102 2.8 19.6 0.1 O A:THR59 2.9 17.8 1.0 C A:VAL60 3.5 15.5 1.0 K A:K104 3.6 18.6 0.2 C A:THR59 4.0 17.4 1.0 CA A:VAL60 4.1 16.2 1.0 N A:GLY61 4.4 17.4 1.0 N A:VAL60 4.5 15.5 1.0 CA A:GLY61 4.6 16.7 1.0 O A:GLY61 4.8 16.9 1.0 C A:GLY61 5.0 16.9 1.0

Potassium binding site 4 out of 5 in the Wild-Type Mthk Pore in 50 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Wild-Type Mthk Pore in 50 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K104 b:18.6 occ:0.25 O A:THR59 2.8 17.8 1.0 OG1 A:THR59 2.8 18.8 1.0 CB A:THR59 3.4 17.9 1.0 K A:K103 3.6 18.6 0.2 C A:THR59 3.7 17.4 1.0 CA A:THR59 4.2 17.1 1.0 CG2 A:THR59 4.7 18.1 1.0 N A:VAL60 4.7 15.5 1.0

Potassium binding site 5 out of 5 in the Wild-Type Mthk Pore in 50 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Wild-Type Mthk Pore in 50 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K105 b:38.4 occ:0.12 O A:HOH231 3.0 41.3 1.0

C.Boiteux, D.J.Posson, T.W.Allen, C.M.Nimigean. Selectivity Filter Ion Binding Affinity Determines Inactivation in A Potassium Channel. Proc.Natl.Acad.Sci.Usa V. 117 29968 2020.
ISSN: ESSN 1091-6490
PubMed: 33154158
DOI: 10.1073/PNAS.2009624117