Potassium in PDB 6u9l: Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM

The structure of Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM, PDB code: 6u9l was solved by E.A.Toth, P.N.Bryan, J.Orban, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.08 / 1.70
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	58.650, 58.650, 124.750, 90.00, 90.00, 90.00
R / Rfree (%)	14.7 / 17.4

The binding sites of Potassium atom in the Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM (pdb code 6u9l). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM, PDB code: 6u9l:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM within 5.0Å range: probe atom residue distance (Å) B Occ S:K301 b:11.3 occ:1.00 O S:ALA169 2.7 11.0 1.0 O S:VAL174 2.7 11.0 1.0 OD2 S:ASP197 2.8 11.9 1.0 O S:HOH460 2.8 15.3 1.0 O S:HOH426 2.9 21.7 1.0 O S:TYR171 2.9 12.3 1.0 O S:GLU195 3.0 10.4 1.0 CB S:ALA176 3.8 8.4 1.0 CG S:ASP197 3.8 11.9 1.0 C S:TYR171 3.8 12.7 1.0 C S:VAL174 3.9 10.7 1.0 C S:ALA169 3.9 9.8 1.0 N S:ALA176 4.0 8.9 1.0 OD1 S:ASP197 4.1 12.0 1.0 C S:GLU195 4.1 11.5 1.0 C S:LYS170 4.2 12.6 1.0 CA S:PRO172 4.2 11.9 1.0 O S:LYS170 4.3 15.9 1.0 NH2 S:ARG247 4.3 13.6 1.0 CB S:GLU195 4.4 11.6 1.0 N S:TYR171 4.5 11.9 1.0 N S:PRO172 4.5 11.7 1.0 O S:PRO172 4.5 10.9 1.0 C S:PRO172 4.5 11.1 1.0 CA S:ALA176 4.5 8.7 1.0 CA S:GLU195 4.5 11.3 1.0 CA S:LYS170 4.6 11.9 1.0 N S:VAL174 4.6 10.0 1.0 CA S:VAL174 4.7 9.8 1.0 N S:LYS170 4.7 9.7 1.0 C S:ILE175 4.7 10.0 1.0 N S:ILE175 4.8 9.6 1.0 CB S:VAL174 4.8 10.4 1.0 CA S:TYR171 4.8 11.8 1.0 CA S:ILE175 4.8 9.4 1.0 CA S:ALA169 4.9 10.1 1.0 O S:HOH413 5.0 27.1 1.0

Potassium binding site 2 out of 3 in the Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM within 5.0Å range: probe atom residue distance (Å) B Occ S:K302 b:19.9 occ:1.00 O S:SER260 2.7 10.0 1.0 O S:LEU196 2.8 11.2 1.0 O S:HOH516 2.8 22.1 1.0 O S:HOH567 2.9 25.7 1.0 O S:GLY193 2.9 10.2 1.0 O S:PRO194 3.1 12.3 1.0 C S:PRO194 3.4 11.6 1.0 CA S:PRO194 3.6 12.8 1.0 C S:SER260 3.6 10.4 1.0 C S:LEU196 3.8 10.5 1.0 C S:GLY193 3.9 10.9 1.0 N S:LEU196 3.9 10.8 1.0 CA S:GLY264 4.0 9.7 1.0 CB S:LEU196 4.0 10.5 1.0 CB S:SER260 4.1 12.5 1.0 CA S:LEU196 4.1 10.7 1.0 O S:HOH436 4.2 22.6 1.0 N S:PRO194 4.2 11.5 1.0 N S:GLU195 4.3 11.1 1.0 N S:PHE261 4.3 10.4 1.0 OG S:SER260 4.3 13.8 1.0 N S:GLY264 4.4 10.3 1.0 CA S:PHE261 4.4 10.7 1.0 CA S:SER260 4.4 11.3 1.0 C S:GLU195 4.7 11.5 1.0 CG S:LEU196 4.7 11.0 1.0 C S:PHE261 4.8 10.5 1.0 O S:PHE261 4.8 10.3 1.0 CB S:PRO194 4.9 13.9 1.0 CA S:GLU195 5.0 11.3 1.0

Potassium binding site 3 out of 3 in the Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Imidazole-Triggered Ras-Specific Subtilisin SUBT_BACAM within 5.0Å range: probe atom residue distance (Å) B Occ S:K303 b:19.2 occ:1.00 O S:HIS39 2.6 16.1 1.0 O S:LEU42 2.7 23.0 1.0 O S:SER37 2.7 16.1 1.0 C S:HIS39 3.7 15.7 1.0 C S:SER37 3.8 15.2 1.0 C S:LEU42 3.9 19.4 1.0 O S:HOH543 3.9 33.9 1.0 C S:SER38 4.0 15.3 1.0 N S:HIS39 4.1 14.8 1.0 O S:SER38 4.2 16.2 1.0 CA S:SER38 4.2 14.8 1.0 CA S:PRO40 4.3 18.7 1.0 OD1 S:ASN43 4.4 33.5 1.0 N S:PRO40 4.5 16.6 1.0 N S:SER38 4.5 14.3 1.0 C S:PRO40 4.5 20.4 1.0 CA S:HIS39 4.5 13.9 1.0 N S:LEU42 4.5 17.5 1.0 O S:PRO40 4.5 22.6 1.0 CA S:LEU42 4.8 17.2 1.0 CA S:ASN43 4.8 19.8 1.0 N S:ASN43 4.8 20.0 1.0 CA S:SER37 4.9 13.3 1.0

E.A.Toth, P.N.Bryan. A Programmable Proteolytic Machine That Specifically Degrades Oncogenic Ras in Vitro, in Engineered Bacteria, and in Human Cell Culture To Be Published.