Potassium in PDB 6rv2: Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Protein crystallography data
The structure of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation, PDB code: 6rv2
was solved by
K.E.J.Rodstrom,
A.C.W.Pike,
W.Zhang,
A.Quigley,
D.Speedman,
S.M.M.Mukhopadhyay,
L.Shrestha,
R.Chalk,
S.Venkaya,
S.R.Bushell,
A.Tessitore,
N.Burgess-Brown,
C.H.Arrowsmith,
A.M.Edwards,
C.Bountra,
E.P.Carpenter,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
47.04 /
3.00
|
Space group
|
P 2 21 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
45.140,
204.790,
238.340,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
25.3 /
25.7
|
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
(pdb code 6rv2). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 8 binding sites of Potassium where determined in the
Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation, PDB code: 6rv2:
Jump to Potassium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Potassium binding site 1 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 1 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K302
b:43.2
occ:1.00
|
O
|
A:ILE94
|
2.7
|
37.9
|
1.0
|
O
|
A:GLY201
|
2.7
|
36.3
|
1.0
|
O
|
B:ILE94
|
2.7
|
35.4
|
1.0
|
O
|
A:ILE200
|
2.7
|
33.1
|
1.0
|
O
|
A:GLY95
|
2.7
|
39.6
|
1.0
|
O
|
B:ILE200
|
2.7
|
39.0
|
1.0
|
O
|
B:GLY201
|
2.8
|
38.1
|
1.0
|
K
|
A:K303
|
2.8
|
33.2
|
1.0
|
O
|
B:GLY95
|
2.8
|
37.7
|
1.0
|
K
|
A:K309
|
3.1
|
33.4
|
1.0
|
C
|
A:GLY201
|
3.6
|
36.6
|
1.0
|
C
|
A:GLY95
|
3.6
|
39.2
|
1.0
|
C
|
B:GLY201
|
3.6
|
37.9
|
1.0
|
C
|
B:GLY95
|
3.6
|
37.9
|
1.0
|
C
|
A:ILE94
|
3.8
|
37.6
|
1.0
|
C
|
B:ILE94
|
3.9
|
35.8
|
1.0
|
C
|
A:ILE200
|
3.9
|
33.4
|
1.0
|
C
|
B:ILE200
|
3.9
|
38.9
|
1.0
|
CA
|
A:GLY201
|
4.1
|
31.0
|
1.0
|
CA
|
B:GLY201
|
4.1
|
34.9
|
1.0
|
CA
|
A:GLY95
|
4.2
|
33.8
|
1.0
|
CA
|
B:GLY95
|
4.2
|
33.3
|
1.0
|
N
|
A:GLY201
|
4.4
|
30.7
|
1.0
|
N
|
A:GLY95
|
4.4
|
33.8
|
1.0
|
N
|
B:GLY201
|
4.4
|
35.4
|
1.0
|
N
|
B:GLY95
|
4.4
|
32.8
|
1.0
|
N
|
A:TYR96
|
4.5
|
35.5
|
1.0
|
N
|
A:PHE202
|
4.6
|
34.4
|
1.0
|
N
|
B:TYR96
|
4.6
|
34.3
|
1.0
|
N
|
B:PHE202
|
4.6
|
33.2
|
1.0
|
O
|
B:THR93
|
4.8
|
33.0
|
1.0
|
CA
|
A:TYR96
|
4.8
|
35.0
|
1.0
|
O
|
A:THR93
|
4.8
|
38.6
|
1.0
|
CA
|
B:TYR96
|
4.9
|
34.3
|
1.0
|
O
|
A:THR199
|
4.9
|
35.1
|
1.0
|
O
|
B:THR199
|
4.9
|
34.3
|
1.0
|
CA
|
A:PHE202
|
4.9
|
34.9
|
1.0
|
CA
|
B:PHE202
|
4.9
|
32.3
|
1.0
|
|
Potassium binding site 2 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 2 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K303
b:33.2
occ:1.00
|
O
|
B:THR93
|
2.6
|
33.0
|
1.0
|
O
|
A:THR93
|
2.7
|
38.6
|
1.0
|
O
|
A:THR199
|
2.7
|
35.1
|
1.0
|
O
|
B:THR199
|
2.7
|
34.3
|
1.0
|
O
|
A:ILE200
|
2.7
|
33.1
|
1.0
|
O
|
B:ILE200
|
2.8
|
39.0
|
1.0
|
K
|
A:K302
|
2.8
|
43.2
|
1.0
|
O
|
B:ILE94
|
2.8
|
35.4
|
1.0
|
O
|
A:ILE94
|
2.8
|
37.9
|
1.0
|
K
|
A:K304
|
3.5
|
40.2
|
1.0
|
C
|
A:ILE200
|
3.6
|
33.4
|
1.0
|
C
|
B:ILE200
|
3.6
|
38.9
|
1.0
|
C
|
B:ILE94
|
3.6
|
35.8
|
1.0
|
C
|
A:ILE94
|
3.6
|
37.6
|
1.0
|
C
|
B:THR93
|
3.8
|
34.8
|
1.0
|
C
|
A:THR93
|
3.8
|
38.5
|
1.0
|
C
|
A:THR199
|
3.8
|
34.6
|
1.0
|
C
|
B:THR199
|
3.8
|
35.0
|
1.0
|
CA
|
B:ILE94
|
4.1
|
31.4
|
1.0
|
CA
|
A:ILE94
|
4.1
|
32.2
|
1.0
|
CA
|
A:ILE200
|
4.1
|
28.1
|
1.0
|
CA
|
B:ILE200
|
4.1
|
33.5
|
1.0
|
N
|
B:ILE94
|
4.4
|
31.5
|
1.0
|
N
|
A:ILE200
|
4.4
|
29.3
|
1.0
|
N
|
B:ILE200
|
4.4
|
32.9
|
1.0
|
N
|
A:ILE94
|
4.4
|
32.8
|
1.0
|
N
|
B:GLY95
|
4.5
|
32.8
|
1.0
|
N
|
A:GLY201
|
4.5
|
30.7
|
1.0
|
N
|
B:GLY201
|
4.5
|
35.4
|
1.0
|
N
|
A:GLY95
|
4.5
|
33.8
|
1.0
|
O
|
A:GLY95
|
4.8
|
39.6
|
1.0
|
O
|
A:GLY201
|
4.8
|
36.3
|
1.0
|
O
|
B:GLY95
|
4.8
|
37.7
|
1.0
|
O
|
B:GLY201
|
4.8
|
38.1
|
1.0
|
CA
|
A:GLY201
|
4.9
|
31.0
|
1.0
|
CA
|
B:GLY201
|
4.9
|
34.9
|
1.0
|
CA
|
B:THR93
|
5.0
|
32.7
|
1.0
|
CA
|
B:GLY95
|
5.0
|
33.3
|
1.0
|
CA
|
A:GLY95
|
5.0
|
33.8
|
1.0
|
|
Potassium binding site 3 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 3 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 3 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K304
b:40.2
occ:1.00
|
O
|
A:THR199
|
2.7
|
35.1
|
1.0
|
OG1
|
A:THR199
|
2.7
|
30.4
|
1.0
|
OG1
|
B:THR93
|
2.7
|
28.2
|
1.0
|
OG1
|
A:THR93
|
2.8
|
33.1
|
1.0
|
O
|
B:THR93
|
2.9
|
33.0
|
1.0
|
O
|
A:THR93
|
2.9
|
38.6
|
1.0
|
O
|
B:THR199
|
2.9
|
34.3
|
1.0
|
OG1
|
B:THR199
|
3.0
|
30.5
|
1.0
|
CB
|
B:THR93
|
3.3
|
31.8
|
1.0
|
CB
|
A:THR199
|
3.3
|
34.8
|
1.0
|
CB
|
A:THR93
|
3.4
|
36.4
|
1.0
|
K
|
A:K303
|
3.5
|
33.2
|
1.0
|
CB
|
B:THR199
|
3.6
|
32.1
|
1.0
|
C
|
A:THR199
|
3.6
|
34.6
|
1.0
|
C
|
B:THR93
|
3.7
|
34.8
|
1.0
|
C
|
A:THR93
|
3.8
|
38.5
|
1.0
|
C
|
B:THR199
|
3.9
|
35.0
|
1.0
|
CA
|
A:THR199
|
4.1
|
31.1
|
1.0
|
CA
|
B:THR93
|
4.1
|
32.7
|
1.0
|
CA
|
A:THR93
|
4.2
|
36.1
|
1.0
|
CA
|
B:THR199
|
4.3
|
30.6
|
1.0
|
CG2
|
B:THR93
|
4.4
|
25.5
|
1.0
|
CG2
|
A:THR199
|
4.5
|
34.2
|
1.0
|
CG2
|
A:THR93
|
4.6
|
34.6
|
1.0
|
N
|
A:ILE200
|
4.7
|
29.3
|
1.0
|
CG2
|
B:THR199
|
4.8
|
29.6
|
1.0
|
N
|
A:ILE94
|
4.8
|
32.8
|
1.0
|
N
|
B:ILE94
|
4.8
|
31.5
|
1.0
|
O
|
A:THR198
|
4.9
|
37.2
|
1.0
|
O
|
A:THR92
|
4.9
|
42.5
|
1.0
|
N
|
B:ILE200
|
4.9
|
32.9
|
1.0
|
O
|
B:THR92
|
5.0
|
38.6
|
1.0
|
|
Potassium binding site 4 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 4 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 4 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K309
b:33.4
occ:1.00
|
O
|
A:TYR96
|
2.8
|
41.2
|
1.0
|
O
|
A:GLY201
|
2.8
|
36.3
|
1.0
|
O
|
B:GLY201
|
2.8
|
38.1
|
1.0
|
O
|
B:TYR96
|
2.8
|
41.4
|
1.0
|
O
|
B:PHE202
|
2.8
|
39.4
|
1.0
|
O
|
A:PHE202
|
2.9
|
40.5
|
1.0
|
O
|
A:GLY95
|
2.9
|
39.6
|
1.0
|
O
|
B:GLY95
|
2.9
|
37.7
|
1.0
|
K
|
A:K302
|
3.1
|
43.2
|
1.0
|
C
|
A:TYR96
|
3.4
|
41.6
|
1.0
|
C
|
B:TYR96
|
3.4
|
41.7
|
1.0
|
C
|
B:PHE202
|
3.5
|
38.3
|
1.0
|
C
|
A:PHE202
|
3.5
|
39.7
|
1.0
|
CA
|
A:TYR96
|
3.8
|
35.0
|
1.0
|
CA
|
B:TYR96
|
3.9
|
34.3
|
1.0
|
C
|
B:GLY201
|
3.9
|
37.9
|
1.0
|
C
|
A:GLY201
|
3.9
|
36.6
|
1.0
|
C
|
A:GLY95
|
3.9
|
39.2
|
1.0
|
CA
|
B:PHE202
|
4.0
|
32.3
|
1.0
|
C
|
B:GLY95
|
4.0
|
37.9
|
1.0
|
CA
|
A:PHE202
|
4.0
|
34.9
|
1.0
|
N
|
A:GLY97
|
4.3
|
40.6
|
1.0
|
N
|
B:GLY97
|
4.3
|
40.8
|
1.0
|
N
|
A:TYR96
|
4.3
|
35.5
|
1.0
|
N
|
B:TYR96
|
4.4
|
34.3
|
1.0
|
N
|
A:GLY203
|
4.4
|
36.0
|
1.0
|
N
|
B:GLY203
|
4.4
|
35.2
|
1.0
|
N
|
B:PHE202
|
4.4
|
33.2
|
1.0
|
N
|
A:PHE202
|
4.4
|
34.4
|
1.0
|
CA
|
A:GLY97
|
4.7
|
42.0
|
1.0
|
CA
|
B:GLY97
|
4.8
|
41.7
|
1.0
|
CA
|
A:GLY203
|
4.8
|
36.2
|
1.0
|
CA
|
B:GLY203
|
4.8
|
35.6
|
1.0
|
O
|
A:ILE94
|
5.0
|
37.9
|
1.0
|
O
|
B:ILE94
|
5.0
|
35.4
|
1.0
|
|
Potassium binding site 5 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 5 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 5 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K301
b:40.6
occ:1.00
|
O
|
C:GLY201
|
2.8
|
43.0
|
1.0
|
O
|
C:TYR96
|
2.8
|
44.5
|
1.0
|
O
|
D:TYR96
|
2.8
|
47.7
|
1.0
|
O
|
D:GLY201
|
2.8
|
44.3
|
1.0
|
O
|
D:PHE202
|
2.8
|
43.1
|
1.0
|
O
|
C:GLY95
|
2.8
|
40.4
|
1.0
|
O
|
C:PHE202
|
2.9
|
41.4
|
1.0
|
O
|
D:GLY95
|
2.9
|
44.3
|
1.0
|
K
|
C:K302
|
3.0
|
0.5
|
1.0
|
C
|
C:TYR96
|
3.4
|
45.4
|
1.0
|
C
|
D:TYR96
|
3.4
|
47.2
|
1.0
|
C
|
C:PHE202
|
3.5
|
42.4
|
1.0
|
C
|
D:PHE202
|
3.5
|
43.7
|
1.0
|
CA
|
C:TYR96
|
3.8
|
40.1
|
1.0
|
CA
|
D:TYR96
|
3.9
|
42.3
|
1.0
|
C
|
C:GLY201
|
3.9
|
42.8
|
1.0
|
C
|
C:GLY95
|
3.9
|
41.2
|
1.0
|
C
|
D:GLY201
|
3.9
|
44.9
|
1.0
|
CA
|
D:PHE202
|
4.0
|
38.9
|
1.0
|
CA
|
C:PHE202
|
4.0
|
37.7
|
1.0
|
C
|
D:GLY95
|
4.0
|
44.6
|
1.0
|
N
|
C:GLY97
|
4.3
|
43.6
|
1.0
|
N
|
D:GLY97
|
4.3
|
43.6
|
1.0
|
N
|
C:TYR96
|
4.3
|
39.4
|
1.0
|
N
|
C:GLY203
|
4.4
|
40.1
|
1.0
|
N
|
D:TYR96
|
4.4
|
42.1
|
1.0
|
N
|
C:PHE202
|
4.4
|
38.2
|
1.0
|
N
|
D:GLY203
|
4.4
|
41.0
|
1.0
|
N
|
D:PHE202
|
4.4
|
39.6
|
1.0
|
CA
|
C:GLY97
|
4.8
|
44.4
|
1.0
|
CA
|
D:GLY97
|
4.8
|
43.8
|
1.0
|
CA
|
C:GLY203
|
4.8
|
40.4
|
1.0
|
CA
|
D:GLY203
|
4.9
|
41.1
|
1.0
|
O
|
C:ILE94
|
4.9
|
39.2
|
1.0
|
|
Potassium binding site 6 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 6 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 6 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K302
b:0.5
occ:1.00
|
O
|
C:GLY201
|
2.7
|
43.0
|
1.0
|
O
|
C:ILE94
|
2.7
|
39.2
|
1.0
|
O
|
D:GLY201
|
2.7
|
44.3
|
1.0
|
O
|
C:GLY95
|
2.7
|
40.4
|
1.0
|
O
|
D:GLY95
|
2.7
|
44.3
|
1.0
|
O
|
C:ILE200
|
2.8
|
41.9
|
1.0
|
O
|
D:ILE94
|
2.8
|
41.5
|
1.0
|
O
|
D:ILE200
|
2.8
|
48.8
|
1.0
|
K
|
C:K303
|
2.8
|
37.2
|
1.0
|
K
|
C:K301
|
3.0
|
40.6
|
1.0
|
C
|
C:GLY201
|
3.6
|
42.8
|
1.0
|
C
|
C:GLY95
|
3.6
|
41.2
|
1.0
|
C
|
D:GLY201
|
3.6
|
44.9
|
1.0
|
C
|
D:GLY95
|
3.6
|
44.6
|
1.0
|
C
|
C:ILE94
|
3.8
|
39.6
|
1.0
|
C
|
C:ILE200
|
3.9
|
42.3
|
1.0
|
C
|
D:ILE94
|
3.9
|
41.1
|
1.0
|
C
|
D:ILE200
|
3.9
|
47.6
|
1.0
|
CA
|
C:GLY201
|
4.1
|
38.3
|
1.0
|
CA
|
D:GLY201
|
4.1
|
42.9
|
1.0
|
CA
|
C:GLY95
|
4.2
|
36.3
|
1.0
|
CA
|
D:GLY95
|
4.2
|
39.4
|
1.0
|
N
|
C:GLY201
|
4.4
|
38.2
|
1.0
|
N
|
C:GLY95
|
4.4
|
36.5
|
1.0
|
N
|
D:GLY201
|
4.4
|
43.5
|
1.0
|
N
|
D:GLY95
|
4.5
|
39.0
|
1.0
|
N
|
C:TYR96
|
4.5
|
39.4
|
1.0
|
N
|
D:TYR96
|
4.5
|
42.1
|
1.0
|
N
|
D:PHE202
|
4.6
|
39.6
|
1.0
|
N
|
C:PHE202
|
4.6
|
38.2
|
1.0
|
CA
|
C:TYR96
|
4.8
|
40.1
|
1.0
|
CA
|
D:TYR96
|
4.8
|
42.3
|
1.0
|
O
|
C:THR93
|
4.9
|
36.4
|
1.0
|
CA
|
D:PHE202
|
4.9
|
38.9
|
1.0
|
O
|
D:THR93
|
4.9
|
37.1
|
1.0
|
CA
|
C:PHE202
|
4.9
|
37.7
|
1.0
|
O
|
C:THR199
|
4.9
|
42.5
|
1.0
|
O
|
D:THR199
|
5.0
|
45.9
|
1.0
|
|
Potassium binding site 7 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 7 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 7 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K303
b:37.2
occ:1.00
|
O
|
C:THR93
|
2.7
|
36.4
|
1.0
|
O
|
C:THR199
|
2.7
|
42.5
|
1.0
|
O
|
D:THR93
|
2.7
|
37.1
|
1.0
|
O
|
D:ILE200
|
2.7
|
48.8
|
1.0
|
O
|
D:THR199
|
2.7
|
45.9
|
1.0
|
O
|
C:ILE200
|
2.8
|
41.9
|
1.0
|
K
|
C:K302
|
2.8
|
0.5
|
1.0
|
O
|
C:ILE94
|
2.8
|
39.2
|
1.0
|
O
|
D:ILE94
|
2.8
|
41.5
|
1.0
|
C
|
D:ILE200
|
3.5
|
47.6
|
1.0
|
C
|
C:ILE94
|
3.6
|
39.6
|
1.0
|
C
|
C:ILE200
|
3.6
|
42.3
|
1.0
|
K
|
C:K304
|
3.6
|
44.6
|
1.0
|
C
|
D:ILE94
|
3.6
|
41.1
|
1.0
|
C
|
C:THR93
|
3.8
|
37.2
|
1.0
|
C
|
C:THR199
|
3.8
|
42.8
|
1.0
|
C
|
D:THR199
|
3.9
|
46.4
|
1.0
|
C
|
D:THR93
|
3.9
|
37.8
|
1.0
|
CA
|
C:ILE94
|
4.0
|
34.6
|
1.0
|
CA
|
D:ILE200
|
4.1
|
41.9
|
1.0
|
CA
|
C:ILE200
|
4.1
|
38.5
|
1.0
|
CA
|
D:ILE94
|
4.1
|
34.3
|
1.0
|
N
|
C:ILE94
|
4.4
|
34.8
|
1.0
|
N
|
C:ILE200
|
4.4
|
39.0
|
1.0
|
N
|
D:ILE200
|
4.4
|
42.4
|
1.0
|
N
|
D:ILE94
|
4.4
|
34.1
|
1.0
|
N
|
C:GLY95
|
4.5
|
36.5
|
1.0
|
N
|
D:GLY201
|
4.5
|
43.5
|
1.0
|
N
|
C:GLY201
|
4.5
|
38.2
|
1.0
|
N
|
D:GLY95
|
4.5
|
39.0
|
1.0
|
O
|
D:GLY95
|
4.8
|
44.3
|
1.0
|
O
|
C:GLY95
|
4.8
|
40.4
|
1.0
|
O
|
D:GLY201
|
4.8
|
44.3
|
1.0
|
O
|
C:GLY201
|
4.8
|
43.0
|
1.0
|
CA
|
D:GLY201
|
4.9
|
42.9
|
1.0
|
CA
|
C:GLY201
|
4.9
|
38.3
|
1.0
|
CA
|
C:GLY95
|
5.0
|
36.3
|
1.0
|
CA
|
D:GLY95
|
5.0
|
39.4
|
1.0
|
CA
|
C:THR93
|
5.0
|
33.7
|
1.0
|
|
Potassium binding site 8 out
of 8 in 6rv2
Go back to
Potassium Binding Sites List in 6rv2
Potassium binding site 8 out
of 8 in the Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 8 of Crystal Structure of the Human Two Pore Domain Potassium Ion Channel Task-1 (K2P3.1) in A Closed Conformation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K304
b:44.6
occ:1.00
|
OG1
|
D:THR93
|
2.7
|
42.5
|
1.0
|
O
|
C:THR199
|
2.8
|
42.5
|
1.0
|
OG1
|
C:THR199
|
2.8
|
38.5
|
1.0
|
OG1
|
C:THR93
|
2.8
|
45.4
|
1.0
|
O
|
D:THR199
|
2.8
|
45.9
|
1.0
|
O
|
D:THR93
|
2.9
|
37.1
|
1.0
|
O
|
C:THR93
|
2.9
|
36.4
|
1.0
|
OG1
|
D:THR199
|
2.9
|
51.1
|
1.0
|
CB
|
D:THR93
|
3.3
|
46.0
|
1.0
|
CB
|
C:THR199
|
3.3
|
40.4
|
1.0
|
CB
|
C:THR93
|
3.4
|
43.8
|
1.0
|
CB
|
D:THR199
|
3.5
|
48.9
|
1.0
|
K
|
C:K303
|
3.6
|
37.2
|
1.0
|
C
|
C:THR199
|
3.7
|
42.8
|
1.0
|
C
|
D:THR93
|
3.7
|
37.8
|
1.0
|
C
|
C:THR93
|
3.8
|
37.2
|
1.0
|
C
|
D:THR199
|
3.8
|
46.4
|
1.0
|
CA
|
C:THR199
|
4.1
|
38.6
|
1.0
|
CA
|
D:THR93
|
4.1
|
35.7
|
1.0
|
CA
|
C:THR93
|
4.2
|
33.7
|
1.0
|
CA
|
D:THR199
|
4.2
|
43.0
|
1.0
|
CG2
|
D:THR93
|
4.5
|
47.2
|
1.0
|
CG2
|
C:THR199
|
4.6
|
37.3
|
1.0
|
CG2
|
C:THR93
|
4.6
|
43.5
|
1.0
|
CG2
|
D:THR199
|
4.7
|
45.4
|
1.0
|
N
|
C:ILE200
|
4.7
|
39.0
|
1.0
|
N
|
D:ILE94
|
4.8
|
34.1
|
1.0
|
N
|
C:ILE94
|
4.8
|
34.8
|
1.0
|
N
|
D:ILE200
|
4.8
|
42.4
|
1.0
|
O
|
C:THR92
|
4.9
|
37.9
|
1.0
|
O
|
C:THR198
|
4.9
|
42.2
|
1.0
|
O
|
D:THR92
|
5.0
|
40.4
|
1.0
|
|
Reference:
K.E.J.Rodstrom,
A.K.Kiper,
W.Zhang,
S.Rinne,
A.C.W.Pike,
M.Goldstein,
L.Conrad,
M.Delbeck,
M.Hahn,
H.Meier,
M.Platzk,
A.Quigley,
D.Speedman,
L.Shrestha,
S.M.M.Mukhopadhyay,
N.A.Burgess-Brown,
S.J.Tucker,
T.Mueller,
N.Decher,
E.P.Carpenter.
A Unique Lower X-Gate in Task Channels Sequesters Inhibitors Within the Vestibule To Be Published.
Page generated: Mon Aug 12 17:30:51 2024
|