Potassium in PDB 6q00: TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1

The structure of TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1, PDB code: 6q00 was solved by M.J.Schellenberg, J.M.Krahn, R.S.Williams, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.45 / 0.85
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	48.742, 48.742, 50.421, 90.00, 90.00, 90.00
R / Rfree (%)	9.5 / 11.2

The binding sites of Potassium atom in the TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1 (pdb code 6q00). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1, PDB code: 6q00:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:K101 b:13.9 occ:0.81 O B:ALA36 2.5 10.5 1.0 O B:HOH210 2.7 31.0 0.9 O B:HOH258 2.7 22.8 0.6 O A:HOH105 2.8 13.2 0.8 OH B:TYR61 2.8 12.3 1.0 O A:GLY47 2.9 12.7 1.0 HE1 B:TYR61 3.3 12.6 1.0 HA3 A:GLY47 3.4 12.5 1.0 HB3 B:SER37 3.5 12.2 1.0 O B:SER37 3.6 11.9 1.0 O A:HOH166 3.7 18.6 0.6 C B:ALA36 3.8 9.1 1.0 CZ B:TYR61 3.8 10.2 1.0 C A:GLY47 3.8 10.6 1.0 CE1 B:TYR61 3.8 10.5 1.0 CA A:GLY47 4.0 10.4 1.0 C B:SER37 4.1 9.6 1.0 HB3 B:CYS38 4.1 12.2 1.0 HA2 A:GLY47 4.3 12.5 1.0 NZ A:LYS48 4.4 36.2 1.0 O A:HOH217 4.4 38.8 0.7 HB2 B:ALA36 4.4 10.8 1.0 CB B:SER37 4.4 10.2 1.0 HA B:ALA36 4.5 10.5 1.0 CA B:SER37 4.6 9.3 1.0 N B:SER37 4.6 8.9 1.0 O B:HOH255 4.7 41.3 0.8 CA B:ALA36 4.7 8.8 1.0 CD A:LYS48 4.7 23.9 1.0 CE A:LYS48 4.7 28.6 1.0 HA B:CYS38 4.9 12.1 1.0 O B:HOH234 4.9 22.8 1.0 N B:CYS38 4.9 9.3 1.0 O A:HOH217 4.9 24.6 0.3 N A:LYS48 5.0 10.1 1.0 HA A:LYS48 5.0 13.2 1.0 HB2 B:SER37 5.0 12.2 1.0

Potassium binding site 2 out of 2 in the TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of TDP2 Uba Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:K102 b:16.5 occ:0.31 O B:HOH243 1.6 24.9 0.5 O B:HOH201 1.9 32.6 0.7 O B:TYR61 2.8 10.8 1.0 O B:GLU63 2.9 19.6 1.0 O B:SER60 2.9 10.3 1.0 O B:HOH248 3.1 28.4 0.6 O B:HOH243 3.3 17.4 0.4 C B:TYR61 3.4 9.2 1.0 HA B:TYR61 3.5 10.4 1.0 O B:HOH248 3.8 14.4 0.1 CA B:TYR61 3.9 8.7 1.0 C B:GLU63 4.0 17.2 1.0 H B:GLU63 4.0 14.2 1.0 C B:SER60 4.0 8.8 1.0 N B:GLU63 4.2 11.8 1.0 HZ B:PHE46 4.2 11.7 1.0 N B:PHE62 4.3 9.4 1.0 O B:HOH229 4.4 28.1 1.0 HB3 B:GLU63 4.4 19.7 1.0 O B:HOH226 4.5 25.5 0.7 N B:TYR61 4.5 8.5 1.0 HA B:PRO64 4.5 29.1 1.0 C B:PHE62 4.5 11.5 1.0 CA B:GLU63 4.6 14.4 1.0 HA B:PHE62 4.6 12.5 1.0 HE1 B:PHE46 4.7 12.9 1.0 CA B:PHE62 4.8 10.4 1.0 CD B:PRO65 4.8 28.3 1.0 N B:PRO65 4.9 26.3 1.0 O B:HOH226 4.9 27.1 0.3 H B:PHE62 4.9 11.3 1.0 N B:PRO64 4.9 20.4 1.0 CZ B:PHE46 5.0 9.7 1.0 C B:PRO64 5.0 23.0 1.0 CA B:PRO64 5.0 24.2 1.0

M.J.Schellenberg, C.D.Appel, A.A.Riccio, L.R.Butler, J.M.Krahn, R.S.Williams. Ubiquitin Stimulated Reversal of Topoisomerase 2 Dna Protein Crosslinks By TDP2 To Be Published.