Potassium in PDB 6phz: Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One

The structure of Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One, PDB code: 6phz was solved by J.D.Osko, D.W.Christianson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.69 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	47.370, 82.360, 90.720, 90.00, 98.22, 90.00
R / Rfree (%)	16.1 / 21.2

The structure of Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Magnesium	(Mg)	4 atoms
Zinc	(Zn)	2 atoms

The binding sites of Potassium atom in the Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One (pdb code 6phz). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One, PDB code: 6phz:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One within 5.0Å range: probe atom residue distance (Å) B Occ A:K401 b:19.3 occ:1.00 O A:LEU217 2.5 5.0 1.0 O A:ASP195 2.5 8.0 1.0 OD1 A:ASP193 2.5 3.8 1.0 O A:HIS197 2.7 4.5 1.0 OG A:SER216 2.7 2.7 1.0 O A:ASP193 3.0 5.9 1.0 CG A:ASP193 3.2 10.7 1.0 C A:ASP195 3.5 4.6 1.0 C A:LEU217 3.5 5.8 1.0 C A:ASP193 3.5 3.8 1.0 C A:HIS197 3.6 6.7 1.0 N A:ASP195 3.7 6.1 1.0 CB A:ASP193 3.7 3.5 1.0 N A:LEU217 3.8 7.0 1.0 CB A:HIS218 3.8 2.3 1.0 CB A:SER216 3.9 7.2 1.0 CA A:ASP195 4.0 6.3 1.0 C A:VAL194 4.0 9.0 1.0 OD2 A:ASP193 4.1 4.5 1.0 N A:VAL194 4.1 7.3 1.0 CA A:ASP193 4.2 4.6 1.0 CB A:ASP195 4.2 3.5 1.0 ND1 A:HIS218 4.2 6.4 1.0 CA A:HIS198 4.3 4.7 1.0 N A:GLY199 4.3 2.4 1.0 N A:HIS198 4.3 4.8 1.0 CA A:SER216 4.3 5.1 1.0 CA A:VAL194 4.3 2.7 1.0 CA A:LEU217 4.3 11.4 1.0 N A:HIS197 4.4 3.7 1.0 CA A:HIS218 4.4 9.9 1.0 C A:SER216 4.4 6.3 1.0 N A:HIS218 4.4 6.4 1.0 O A:HOH604 4.4 7.7 1.0 C A:PHE196 4.5 6.8 1.0 CG A:HIS218 4.5 7.0 1.0 C A:HIS198 4.5 6.9 1.0 N A:PHE196 4.6 3.8 1.0 CA A:HIS197 4.6 4.3 1.0 O A:VAL194 4.7 5.5 1.0 O A:PHE196 4.8 4.0 1.0 OD1 A:ASP195 4.9 5.8 1.0 CA A:PHE196 5.0 3.5 1.0 CE1 A:HIS158 5.0 7.0 1.0

Potassium binding site 2 out of 4 in the Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One within 5.0Å range: probe atom residue distance (Å) B Occ A:K402 b:12.1 occ:1.00 O A:VAL212 2.7 6.7 1.0 O A:PHE206 2.8 5.8 1.0 O A:HOH544 2.9 4.8 1.0 O A:ARG209 2.9 8.7 1.0 O A:TYR243 3.0 8.6 1.0 O A:HOH532 3.1 6.0 1.0 C A:PHE206 3.7 8.2 1.0 C A:TYR243 3.7 12.6 1.0 CB A:TYR243 3.7 9.6 1.0 OG1 A:THR214 3.9 6.8 1.0 C A:VAL212 3.9 14.9 1.0 CB A:PHE206 4.0 7.0 1.0 C A:ARG209 4.0 12.9 1.0 CA A:TYR243 4.4 8.5 1.0 N A:THR214 4.4 7.5 1.0 N A:ARG209 4.4 7.1 1.0 CA A:TYR207 4.4 11.0 1.0 CA A:PHE206 4.5 9.9 1.0 N A:TYR207 4.5 7.0 1.0 N A:ASN244 4.5 6.8 1.0 CA A:LEU213 4.5 9.0 1.0 C A:TYR207 4.5 15.3 1.0 O A:TYR207 4.5 9.8 1.0 CG2 A:THR214 4.6 8.2 1.0 N A:LEU213 4.7 7.3 1.0 CA A:ARG209 4.7 9.3 1.0 CB A:THR214 4.8 8.6 1.0 O A:GLY240 4.8 16.3 1.0 C A:LEU213 4.8 8.1 1.0 CB A:ARG209 4.9 11.4 1.0 CA A:ASN244 4.9 6.5 1.0 CA A:VAL212 4.9 9.6 1.0 CB A:ASN244 4.9 7.3 1.0 CA A:GLY240 5.0 9.4 1.0

Potassium binding site 3 out of 4 in the Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One within 5.0Å range: probe atom residue distance (Å) B Occ B:K401 b:22.8 occ:1.00 O B:LEU217 2.5 7.2 1.0 OD1 B:ASP193 2.5 4.2 1.0 O B:ASP195 2.6 6.1 1.0 OG B:SER216 2.7 6.9 1.0 O B:HIS197 2.7 4.8 1.0 O B:ASP193 2.9 10.3 1.0 CG B:ASP193 3.2 10.1 1.0 C B:ASP193 3.5 8.5 1.0 C B:LEU217 3.5 9.8 1.0 C B:ASP195 3.6 10.3 1.0 CB B:ASP193 3.6 10.0 1.0 C B:HIS197 3.7 5.8 1.0 N B:LEU217 3.7 5.4 1.0 N B:ASP195 3.8 8.9 1.0 CB B:SER216 3.9 6.4 1.0 CB B:HIS218 3.9 7.5 1.0 N B:VAL194 4.1 5.2 1.0 CA B:ASP195 4.1 6.0 1.0 OD2 B:ASP193 4.1 9.5 1.0 C B:VAL194 4.1 9.4 1.0 CA B:ASP193 4.2 4.9 1.0 CA B:SER216 4.2 7.7 1.0 CA B:HIS198 4.2 7.8 1.0 N B:GLY199 4.2 5.7 1.0 ND1 B:HIS218 4.2 6.1 1.0 CA B:LEU217 4.3 8.6 1.0 C B:SER216 4.3 10.0 1.0 CA B:VAL194 4.3 7.2 1.0 CB B:ASP195 4.3 9.9 1.0 N B:HIS198 4.3 4.6 1.0 CA B:HIS218 4.4 6.8 1.0 N B:HIS218 4.4 9.3 1.0 N B:HIS197 4.4 8.6 1.0 O B:HOH599 4.5 14.9 1.0 CG B:HIS218 4.5 6.2 1.0 C B:PHE196 4.5 10.4 1.0 C B:HIS198 4.6 5.6 1.0 CA B:HIS197 4.7 6.3 1.0 N B:PHE196 4.7 10.0 1.0 O B:PHE196 4.8 7.7 1.0 O B:VAL194 4.8 4.7 1.0

Potassium binding site 4 out of 4 in the Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of Marinobacter Subterrani Acetylpolyamine Amidohydrolase (Msapah) Complexed with 7-[(3-Aminopropyl)Amino]-1,1, 1-Trifluoroheptan-2-One within 5.0Å range: probe atom residue distance (Å) B Occ B:K402 b:13.3 occ:1.00 O B:VAL212 2.7 5.5 1.0 O B:PHE206 2.7 10.8 1.0 O B:HOH524 2.8 4.8 1.0 O B:TYR243 2.8 8.7 1.0 O B:HOH518 2.8 5.8 1.0 O B:ARG209 2.9 5.0 1.0 OG1 B:THR214 3.6 9.6 1.0 C B:TYR243 3.6 9.3 1.0 C B:PHE206 3.7 9.3 1.0 CB B:TYR243 3.7 9.9 1.0 CB B:PHE206 3.9 11.0 1.0 C B:VAL212 4.0 7.1 1.0 C B:ARG209 4.1 12.2 1.0 CA B:TYR243 4.3 9.6 1.0 N B:THR214 4.3 7.2 1.0 CA B:PHE206 4.4 7.5 1.0 CA B:TYR207 4.4 11.4 1.0 O B:TYR207 4.5 8.0 1.0 N B:TYR207 4.5 10.8 1.0 N B:ASN244 4.5 6.1 1.0 N B:ARG209 4.6 10.1 1.0 C B:TYR207 4.6 9.8 1.0 CA B:LEU213 4.6 12.8 1.0 CB B:THR214 4.6 9.6 1.0 CG2 B:THR214 4.7 12.2 1.0 N B:LEU213 4.7 9.9 1.0 CA B:ARG209 4.7 12.2 1.0 O B:GLY240 4.8 11.0 1.0 C B:LEU213 4.8 9.5 1.0 CB B:ASN244 4.8 5.5 1.0 CA B:ASN244 4.9 7.3 1.0 CB B:ARG209 4.9 15.5 1.0

J.D.Osko, B.W.Roose, S.A.Shinsky, D.W.Christianson. Structure and Function of the Acetylpolyamine Amidohydrolase From the Deep Earth Halophilemarinobacter Subterrani. Biochemistry V. 58 3755 2019.
ISSN: ISSN 0006-2960
PubMed: 31436969
DOI: 10.1021/ACS.BIOCHEM.9B00582