Potassium in PDB 6m84: Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2

The structure of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2, PDB code: 6m84 was solved by S.-J.Lee, F.Ren, P.Yuan, C.G.Nichols, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.81
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	82.787, 82.787, 182.976, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 26.9

The binding sites of Potassium atom in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 (pdb code 6m84). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2, PDB code: 6m84:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ A:K401 b:0.0 occ:0.25 K A:K402 3.3 79.7 0.2 O A:TYR146 3.4 65.6 1.0 C A:TYR146 4.6 62.3 1.0 CA A:GLY147 4.6 63.2 1.0 C A:GLY147 5.0 64.2 1.0

Potassium binding site 2 out of 6 in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ A:K402 b:79.7 occ:0.25 K A:K403 2.9 95.2 0.2 O A:TYR146 2.9 65.6 1.0 O A:GLY145 3.2 64.8 1.0 K A:K401 3.3 0.0 0.3 C A:TYR146 3.7 62.3 1.0 CA A:TYR146 4.3 62.8 1.0 C A:GLY145 4.4 66.9 1.0 N A:GLY147 4.5 62.8 1.0 CA A:GLY147 4.6 63.2 1.0 N A:TYR146 4.9 67.2 1.0

Potassium binding site 3 out of 6 in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ A:K403 b:95.2 occ:0.25 K A:K404 2.9 63.2 0.2 O A:GLY145 2.9 64.8 1.0 K A:K402 2.9 79.7 0.2 O A:ILE144 3.2 66.5 1.0 C A:GLY145 3.8 66.9 1.0 C A:ILE144 4.3 66.0 1.0 CA A:GLY145 4.4 65.4 1.0 N A:TYR146 4.7 67.2 1.0 N A:GLY145 4.9 66.8 1.0 CA A:TYR146 4.9 62.8 1.0 O A:TYR146 4.9 65.6 1.0

Potassium binding site 4 out of 6 in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ A:K404 b:63.2 occ:0.25 O A:ILE144 2.9 66.5 1.0 K A:K403 2.9 95.2 0.2 O A:THR143 3.1 62.0 1.0 C A:ILE144 3.8 66.0 1.0 K A:K405 3.9 69.0 0.2 C A:THR143 4.2 62.2 1.0 CA A:ILE144 4.3 66.1 1.0 N A:GLY145 4.8 66.8 1.0 N A:ILE144 4.8 67.1 1.0 O A:GLY145 4.8 64.8 1.0

Potassium binding site 5 out of 6 in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ A:K405 b:69.0 occ:0.25 OG1 A:THR143 2.9 61.1 1.0 O A:THR143 3.1 62.0 1.0 K A:K404 3.9 63.2 0.2 CB A:THR143 3.9 64.4 1.0 C A:THR143 4.1 62.2 1.0 CA A:THR143 4.7 63.6 1.0 O A:THR142 4.8 64.9 1.0

Potassium binding site 6 out of 6 in the Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Crystal Structure of CKIR2.2 Force Open Mutant in Complex with Pi(4, 5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ A:K406 b:0.9 occ:0.25 CE A:MET181 4.4 0.2 1.0

S.-J.Lee, C.G.Nichols. Potassium Conduction Through A Eukaryotic Inwardly Rectifying Potassium Channel To Be Published.