Potassium in PDB 6i4g: Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State

The structure of Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State, PDB code: 6i4g was solved by E.-P.Kumpula, A.J.Lopez, L.Tajedin, H.Han, I.Kursula, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.80 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.610, 110.620, 138.830, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 25.7

The structure of Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Calcium	(Ca)	4 atoms

The binding sites of Potassium atom in the Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State (pdb code 6i4g). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State, PDB code: 6i4g:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State within 5.0Å range: probe atom residue distance (Å) B Occ A:K403 b:37.8 occ:0.91 O A:HOH503 2.9 42.4 1.0 O2G A:ATP401 2.9 30.6 1.0 O A:VAL160 2.9 30.8 1.0 H A:GLY157 3.0 32.1 1.0 O1G A:ATP401 3.1 28.8 1.0 OD1 A:ASP155 3.2 43.0 0.8 HG13 A:VAL160 3.3 51.5 1.0 HG12 A:VAL160 3.3 51.5 1.0 OD1 A:ASP155 3.3 44.5 0.2 PG A:ATP401 3.4 28.2 1.0 N A:GLY157 3.5 27.1 1.0 O A:HOH550 3.6 26.4 1.0 CG A:ASP155 3.6 35.5 0.8 HA3 A:GLY157 3.6 39.5 1.0 CG1 A:VAL160 3.7 42.8 1.0 HA A:SER156 3.8 39.3 1.0 HB2 A:ASP155 3.9 37.1 0.2 OD2 A:ASP155 3.9 39.6 0.8 C A:VAL160 3.9 32.7 1.0 O A:HOH510 4.0 23.0 1.0 H A:VAL160 4.0 50.4 1.0 HA A:SER161 4.1 35.1 1.0 O A:ASP155 4.1 33.5 1.0 CA A:GLY157 4.1 32.9 1.0 MG A:MG402 4.1 29.2 1.0 C A:SER156 4.2 31.9 1.0 C A:ASP155 4.3 29.4 1.0 HB3 A:ASP155 4.3 36.9 0.8 CG A:ASP155 4.3 35.2 0.2 CA A:SER156 4.3 32.7 1.0 HG11 A:VAL160 4.3 51.5 1.0 N A:SER156 4.4 30.4 1.0 CB A:ASP155 4.5 30.7 0.8 CB A:ASP155 4.5 30.8 0.2 O3G A:ATP401 4.6 28.1 1.0 N A:VAL160 4.7 41.9 1.0 CA A:VAL160 4.7 36.2 1.0 N A:SER161 4.8 28.3 1.0 O3B A:ATP401 4.8 26.1 1.0 HA2 A:GLY157 4.8 39.5 1.0 H A:SER156 4.8 36.5 1.0 CA A:SER161 4.8 29.2 1.0 CB A:VAL160 4.9 35.1 1.0 OE1 A:GLN138 4.9 35.0 1.0 O A:HOH514 4.9 37.8 1.0 H A:HIS162 5.0 33.6 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Plasmodium Falciparum Actin I (H74Q) in the Mg-K- Atp State within 5.0Å range: probe atom residue distance (Å) B Occ B:K403 b:23.1 occ:0.69 H B:GLY157 2.9 29.0 1.0 O B:VAL160 2.9 21.6 1.0 O B:HOH515 3.0 28.6 1.0 O2G B:ATP401 3.1 24.1 1.0 O B:HOH577 3.2 38.0 1.0 O1G B:ATP401 3.2 24.1 1.0 HG13 B:VAL160 3.4 36.5 1.0 N B:GLY157 3.4 24.1 1.0 O B:HOH518 3.5 20.4 1.0 HA3 B:GLY157 3.5 28.6 1.0 OD1 B:ASP155 3.5 65.6 1.0 HG12 B:VAL160 3.6 36.5 1.0 PG B:ATP401 3.6 23.6 1.0 CG B:ASP155 3.6 58.3 1.0 OD2 B:ASP155 3.6 62.6 1.0 O B:HOH513 3.7 17.8 1.0 HA B:SER156 3.8 32.1 1.0 O B:ASP155 3.9 28.8 1.0 C B:VAL160 3.9 25.9 1.0 CG1 B:VAL160 3.9 30.3 1.0 HA B:SER161 4.0 36.9 1.0 CA B:GLY157 4.0 23.8 1.0 MG B:MG402 4.0 22.3 1.0 H B:VAL160 4.1 40.6 1.0 C B:SER156 4.1 25.0 1.0 C B:ASP155 4.1 29.4 1.0 HB3 B:ASP155 4.2 48.0 1.0 CA B:SER156 4.3 26.7 1.0 N B:SER156 4.3 27.2 1.0 CB B:ASP155 4.5 40.0 1.0 HG11 B:VAL160 4.5 36.5 1.0 HA2 B:GLY157 4.6 28.6 1.0 O3G B:ATP401 4.6 24.6 1.0 N B:SER161 4.7 28.4 1.0 CA B:SER161 4.8 30.7 1.0 O B:HOH556 4.8 29.7 1.0 N B:VAL160 4.8 33.8 1.0 CA B:VAL160 4.8 30.9 1.0 H B:SER156 4.8 32.7 1.0 OE1 B:GLN138 4.9 30.8 1.0 H B:HIS162 4.9 30.6 1.0 CA B:ASP155 5.0 32.0 1.0 C B:GLY157 5.0 29.6 1.0

E.P.Kumpula, A.J.Lopez, L.Tajedin, H.Han, I.Kursula. Atomic View Into Plasmodium Actin Polymerization, Atp Hydrolysis, and Fragmentation. Plos Biol. V. 17 00315 2019.
ISSN: ESSN 1545-7885
PubMed: 31199804
DOI: 10.1371/JOURNAL.PBIO.3000315