Potassium in PDB 6fq2: Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation

The structure of Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation, PDB code: 6fq2 was solved by E.Schmitt, Y.Mechulam, A.T.Phan, B.Heddi, B.Bakalar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.46 / 2.31
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	30.557, 30.557, 53.662, 90.00, 90.00, 120.00
R / Rfree (%)	19.6 / 22.7

The binding sites of Potassium atom in the Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation (pdb code 6fq2). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation, PDB code: 6fq2:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation within 5.0Å range: probe atom residue distance (Å) B Occ A:K101 b:25.6 occ:1.00 O6 A:DG4 2.6 25.8 1.0 O6 A:DG7 2.7 24.5 1.0 O6 A:DG10 2.7 24.9 1.0 O6 A:DG1 2.8 25.4 1.0 O6 B:DG4 3.0 27.8 1.0 O6 B:DG1 3.1 44.6 1.0 O6 B:DG10 3.2 28.1 1.0 O6 B:DG7 3.2 30.0 1.0 K A:K102 3.3 27.1 1.0 C6 A:DG4 3.4 26.0 1.0 C6 A:DG7 3.5 24.9 1.0 C6 A:DG10 3.6 25.7 1.0 C6 A:DG1 3.7 26.2 1.0 N1 A:DG4 3.7 25.7 1.0 C6 B:DG4 3.7 28.3 1.0 N1 A:DG7 3.8 25.2 1.0 C6 B:DG1 3.9 31.2 1.0 N1 A:DG1 4.0 26.6 1.0 C6 B:DG10 4.0 28.5 1.0 N1 B:DG4 4.0 28.5 1.0 N1 A:DG10 4.0 26.2 1.0 C6 B:DG7 4.1 47.2 1.0 N1 B:DG1 4.1 29.7 1.0 N1 B:DG10 4.2 28.4 1.0 K B:K101 4.2 29.6 1.0 N1 B:DG7 4.4 31.1 1.0 C5 A:DG4 4.7 27.3 1.0 C5 A:DG7 4.7 25.7 1.0 C5 A:DG10 4.8 29.5 1.0 C5 B:DG4 4.9 29.2 1.0 C5 A:DG1 4.9 27.5 1.0 C2 A:DG4 5.0 28.1 1.0

Potassium binding site 2 out of 3 in the Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation within 5.0Å range: probe atom residue distance (Å) B Occ A:K102 b:27.1 occ:1.00 O6 A:DG10 2.7 24.9 1.0 O6 A:DG1 2.8 25.4 1.0 O6 A:DG4 2.8 25.8 1.0 O6 A:DG12 2.9 27.6 1.0 O6 A:DG7 3.0 24.5 1.0 O6 A:DG6 3.0 35.3 1.0 O6 A:DG3 3.0 30.6 1.0 O6 A:DG9 3.2 52.9 1.0 K A:K101 3.3 25.6 1.0 C6 A:DG12 3.6 28.2 1.0 C6 A:DG1 3.7 26.2 1.0 C6 A:DG3 3.7 39.5 1.0 C6 A:DG10 3.7 25.7 1.0 C6 A:DG6 3.7 28.1 1.0 N1 A:DG12 3.8 28.4 1.0 C6 A:DG4 3.8 26.0 1.0 C6 A:DG9 3.8 56.7 1.0 O A:HOH202 3.9 30.9 1.0 N1 A:DG3 3.9 37.2 1.0 C6 A:DG7 3.9 24.9 1.0 N1 A:DG6 4.0 34.8 1.0 N1 A:DG1 4.0 26.6 1.0 N1 A:DG9 4.0 40.1 1.0 N1 A:DG10 4.1 26.2 1.0 N1 A:DG4 4.1 25.7 1.0 N1 A:DG7 4.2 25.2 1.0 C5 A:DG12 4.8 29.4 1.0 C5 A:DG6 4.8 28.8 1.0 C5 A:DG3 4.8 40.5 1.0 C5 A:DG1 4.9 27.5 1.0 C5 A:DG9 4.9 46.9 1.0 C5 A:DG10 4.9 29.5 1.0 C2 A:DG12 4.9 29.7 1.0 C5 A:DG4 4.9 27.3 1.0

Potassium binding site 3 out of 3 in the Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of Minimal Sequence For Left -Handed G-Quadruplex Formation within 5.0Å range: probe atom residue distance (Å) B Occ B:K101 b:29.6 occ:1.00 O6 B:DG12 2.8 35.5 1.0 O6 B:DG9 2.8 50.0 1.0 O6 B:DG10 2.9 28.1 1.0 O6 B:DG6 2.9 52.9 1.0 O6 B:DG1 3.1 44.6 1.0 O6 B:DG7 3.1 30.0 1.0 O6 B:DG3 3.2 61.3 1.0 O6 B:DG4 3.2 27.8 1.0 C6 B:DG9 3.5 35.8 1.0 C6 B:DG6 3.6 39.3 1.0 N1 B:DG9 3.6 35.4 1.0 C6 B:DG12 3.6 35.6 1.0 C6 B:DG10 3.7 28.5 1.0 N1 B:DG6 3.7 52.8 1.0 N1 B:DG12 3.9 35.7 1.0 C6 B:DG3 3.9 41.4 1.0 C6 B:DG1 3.9 31.2 1.0 O B:HOH205 3.9 29.0 1.0 C6 B:DG7 4.0 47.2 1.0 N1 B:DG10 4.1 28.4 1.0 N1 B:DG3 4.1 48.6 1.0 C6 B:DG4 4.1 28.3 1.0 K A:K101 4.2 25.6 1.0 N1 B:DG7 4.3 31.1 1.0 N1 B:DG1 4.3 29.7 1.0 N1 B:DG4 4.5 28.5 1.0 C5 B:DG9 4.6 36.7 1.0 C2 B:DG9 4.8 36.2 1.0 C5 B:DG6 4.8 41.6 1.0 C5 B:DG12 4.8 36.4 1.0 C5 B:DG10 4.9 29.6 1.0 C2 B:DG6 4.9 37.1 1.0

B.Bakalar, B.Heddi, E.Schmitt, Y.Mechulam, A.T.Phan. A Minimal Sequence For Left-Handed G-Quadruplex Formation. Angew. Chem. Int. Ed. Engl. V. 58 2331 2019.
ISSN: ESSN 1521-3773
PubMed: 30481397
DOI: 10.1002/ANIE.201812628