Potassium in PDB 6fi0: Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19

The structure of Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19, PDB code: 6fi0 was solved by A.Amato, X.Lucas, A.Bortoluzzi, D.Wright, A.Ciulli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.34 / 1.90
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	72.095, 72.095, 99.198, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 23.1

The structure of Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19 also contains other interesting chemical elements:

Zinc

(Zn)

8 atoms

The binding sites of Potassium atom in the Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19 (pdb code 6fi0). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19, PDB code: 6fi0:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19 within 5.0Å range: probe atom residue distance (Å) B Occ A:K1804 b:60.5 occ:1.00 O D:HOH1923 2.4 45.9 1.0 O D:LYS1676 2.7 51.2 1.0 O D:HOH1937 2.8 51.6 1.0 O D:HOH1927 2.9 28.7 1.0 O A:GLY1696 3.0 39.2 1.0 C A:GLY1696 3.9 39.6 1.0 C D:LYS1676 3.9 50.7 1.0 OG1 D:THR1678 4.0 39.2 1.0 CA A:GLY1696 4.1 38.0 1.0 N D:THR1678 4.2 34.5 1.0 O A:HOH1930 4.2 39.2 1.0 CG2 D:THR1678 4.3 38.7 1.0 O D:HOH1911 4.3 46.0 1.0 CA D:VAL1677 4.4 39.6 1.0 C D:VAL1677 4.6 36.6 1.0 N D:VAL1677 4.6 44.4 1.0 SG A:CYS1723 4.7 31.7 1.0 CB D:THR1678 4.7 36.8 1.0 O A:HOH1910 4.9 35.7 1.0 O D:ASP1698 4.9 33.6 1.0 CA D:LYS1676 5.0 54.6 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of BAZ2A Phd Zinc Finger in Complex with Fr 19 within 5.0Å range: probe atom residue distance (Å) B Occ C:K1805 b:38.6 occ:1.00 O C:HOH1926 2.4 45.8 1.0 O C:HOH1935 2.7 41.1 1.0 O C:HOH1917 2.7 24.1 1.0 O C:LYS1676 2.7 35.0 1.0 C C:LYS1676 3.7 37.6 1.0 N C:THR1678 4.3 29.6 1.0 CA C:VAL1677 4.3 31.0 1.0 O C:ASP1698 4.4 29.2 1.0 CG2 C:THR1678 4.4 32.3 1.0 OG1 C:THR1678 4.4 32.2 1.0 N C:VAL1677 4.5 33.9 1.0 N C:LYS1676 4.5 44.0 1.0 C C:VAL1677 4.6 30.5 1.0 CA C:LYS1676 4.6 41.5 1.0 CB C:THR1678 4.9 31.8 1.0 CB C:LYS1676 4.9 43.8 1.0

A.Amato, X.Lucas, A.Bortoluzzi, D.Wright, A.Ciulli. Targeting Ligandable Pockets on Plant Homeodomain (Phd) Zinc Finger Domains By A Fragment-Based Approach. Acs Chem. Biol. V. 13 915 2018.
ISSN: ESSN 1554-8937
PubMed: 29529862
DOI: 10.1021/ACSCHEMBIO.7B01093