Potassium »
PDB 6dxz-6f3n »
6eo6 »
Potassium in PDB 6eo6: X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
Enzymatic activity of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
All present enzymatic activity of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue:
3.4.21.5;
3.4.21.5;
Protein crystallography data
The structure of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue, PDB code: 6eo6
was solved by
R.M.Dolot,
B.Nawrot,
X.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 81.49 / 1.69 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 94.095, 94.095, 124.710, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 14.5 / 16.8 |
Other elements in 6eo6:
The structure of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Potassium Binding Sites:
The binding sites of Potassium atom in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
(pdb code 6eo6). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue, PDB code: 6eo6:
In total only one binding site of Potassium was determined in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue, PDB code: 6eo6:
Potassium binding site 1 out of 1 in 6eo6
Go back to
Potassium Binding Sites List in 6eo6
Potassium binding site 1 out
of 1 in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue within 5.0Å range:
|
Reference:
R.Dolot,
C.H.Lam,
M.Sierant,
Q.Zhao,
F.W.Liu,
B.Nawrot,
M.Egli,
X.Yang.
Crystal Structures of Thrombin in Complex with Chemically Modified Thrombin Dna Aptamers Reveal the Origins of Enhanced Affinity. Nucleic Acids Res. V. 46 4819 2018.
ISSN: ESSN 1362-4962
PubMed: 29684204
DOI: 10.1093/NAR/GKY268
Page generated: Mon Aug 12 16:01:00 2024
ISSN: ESSN 1362-4962
PubMed: 29684204
DOI: 10.1093/NAR/GKY268
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
