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Potassium in PDB 6eo6: X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
Enzymatic activity of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
All present enzymatic activity of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue:
3.4.21.5;
3.4.21.5;
Protein crystallography data
The structure of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue, PDB code: 6eo6
was solved by
R.M.Dolot,
B.Nawrot,
X.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 81.49 / 1.69 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 94.095, 94.095, 124.710, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 14.5 / 16.8 |
Other elements in 6eo6:
The structure of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Potassium Binding Sites:
The binding sites of Potassium atom in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
(pdb code 6eo6). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue, PDB code: 6eo6:
In total only one binding site of Potassium was determined in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue, PDB code: 6eo6:
Potassium binding site 1 out of 1 in 6eo6
Go back to
Potassium Binding Sites List in 6eo6
Potassium binding site 1 out
of 1 in the X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of X-Ray Structure of the Complex Between Human Alpha-Thrombin and Modified 15-Mer Dna Aptamer Containing 5-(3-(2-(1H-Indol-3-Yl) Acetamide-N-Yl)-1-Propen-1-Yl)-2'-Deoxyuridine Residue within 5.0Å range:
|
Reference:
R.Dolot,
C.H.Lam,
M.Sierant,
Q.Zhao,
F.W.Liu,
B.Nawrot,
M.Egli,
X.Yang.
Crystal Structures of Thrombin in Complex with Chemically Modified Thrombin Dna Aptamers Reveal the Origins of Enhanced Affinity. Nucleic Acids Res. V. 46 4819 2018.
ISSN: ESSN 1362-4962
PubMed: 29684204
DOI: 10.1093/NAR/GKY268
Page generated: Mon Aug 12 16:01:00 2024
ISSN: ESSN 1362-4962
PubMed: 29684204
DOI: 10.1093/NAR/GKY268
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