Atomistry » Potassium » PDB 6dxz-6f3n » 6dxz
Atomistry »
  Potassium »
    PDB 6dxz-6f3n »
      6dxz »

Potassium in PDB 6dxz: Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100

Enzymatic activity of Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100

All present enzymatic activity of Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100:
3.5.1.60;

Protein crystallography data

The structure of Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100, PDB code: 6dxz was solved by A.Gorelik, A.Gebai, K.Illes, D.Piomelli, B.Nagar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.94 / 2.70
Space group P 43 3 2
Cell size a, b, c (Å), α, β, γ (°) 159.143, 159.143, 159.143, 90.00, 90.00, 90.00
R / Rfree (%) 18.2 / 22.2

Other elements in 6dxz:

The structure of Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100 also contains other interesting chemical elements:

Fluorine (F) 1 atom

Potassium Binding Sites:

The binding sites of Potassium atom in the Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100 (pdb code 6dxz). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100, PDB code: 6dxz:

Potassium binding site 1 out of 1 in 6dxz

Go back to Potassium Binding Sites List in 6dxz
Potassium binding site 1 out of 1 in the Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Rabbit N-Acylethanolamine-Hydrolyzing Acid Amidase (Naaa) in Complex with Non-Covalent Benzothiazole-Piperazine Inhibitor ARN19702, in Presence of Triton X-100 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K203

b:82.5
occ:1.00
 O A:ARG55 2.7 56.3 1.0
O A:HOH329 3.0 43.8 1.0
O A:TYR57 3.2 44.5 1.0
C A:ARG55 3.8 34.8 1.0
HA A:ARG55 3.9 54.5 0.6
HA A:ARG55 3.9 52.7 0.4
C A:TYR57 3.9 39.1 1.0
H A:TYR57 4.0 39.1 1.0
HA A:ASP58 4.0 49.7 1.0
HG23 A:VAL59 4.2 84.8 1.0
N A:TYR57 4.3 32.5 1.0
H A:VAL59 4.3 45.5 1.0
HG2 A:ARG55 4.4 47.8 0.6
CA A:ARG55 4.4 45.3 0.6
CA A:ARG55 4.4 43.8 0.4
O A:LEU54 4.5 36.3 1.0
HG3 A:ARG55 4.5 47.8 0.4
N A:ASP58 4.6 37.5 1.0
HG2 A:ARG55 4.7 47.8 0.4
C A:HIS56 4.7 31.3 1.0
CA A:ASP58 4.7 41.4 1.0
CA A:TYR57 4.7 38.7 1.0
N A:HIS56 4.8 39.1 1.0
HA A:HIS56 4.8 36.3 1.0
HG3 A:ARG55 4.9 47.8 0.6
N A:VAL59 4.9 37.9 1.0

Reference:

A.Gorelik, A.Gebai, K.Illes, D.Piomelli, B.Nagar. Molecular Mechanism of Activation of the Immunoregulatory Amidase Naaa. Proc. Natl. Acad. Sci. V. 115 10032 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30301806
DOI: 10.1073/PNAS.1811759115
Page generated: Mon Aug 12 15:57:47 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy