Potassium in PDB 5y7x: Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist

The structure of Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist, PDB code: 5y7x was solved by H.L.Kim, J.W.Chin, S.J.Cho, J.Y.Song, H.S.Yoon, J.H.Bae, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.66 / 1.70
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	39.766, 93.896, 96.871, 90.00, 97.40, 90.00
R / Rfree (%)	20.5 / 23.1

The structure of Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Chlorine	(Cl)	2 atoms

The binding sites of Potassium atom in the Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist (pdb code 5y7x). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist, PDB code: 5y7x:

Potassium binding site 1 out of 1 in the Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Peroxisome Proliferator-Activated Receptor (Ppar) Delta in Complexed with A Potent and Selective Agonist within 5.0Å range: probe atom residue distance (Å) B Occ A:K502 b:39.0 occ:1.00 O A:HOH698 3.0 33.7 1.0 ND2 A:ASN339 3.2 26.7 1.0 O A:HOH614 3.3 33.9 1.0 NH2 A:ARG198 3.6 36.1 1.0 CB A:ASN339 3.7 28.1 1.0 CA A:ASN299 3.7 33.2 1.0 O A:VAL298 3.8 29.3 1.0 CG A:ASN339 3.9 25.1 1.0 CB A:ASN299 4.2 31.9 1.0 CA A:VAL336 4.2 30.7 1.0 N A:LYS300 4.3 31.2 1.0 C A:ASN299 4.3 31.0 1.0 CG2 A:VAL336 4.3 30.9 1.0 CG1 A:VAL336 4.6 34.5 1.0 C A:VAL298 4.6 30.5 1.0 CB A:VAL336 4.6 32.7 1.0 O A:HOH754 4.7 42.4 1.0 N A:ASN299 4.7 29.4 1.0 O A:VAL336 4.7 31.3 1.0 CZ A:ARG198 4.8 37.5 1.0 O A:ALA335 4.8 27.8 1.0 C A:VAL336 5.0 28.6 1.0

J.W.Chin, S.J.Cho. Design, Synthesis, and the X-Ray Co-Crystal Structure of Highly Potent, Selective, and Orally Bioavailable, Novel Peroxisome Proliferator-Activated Receptor Delta Agonists To Be Published.