Potassium in PDB 5xxi: Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules
Enzymatic activity of Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules
All present enzymatic activity of Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules:
1.14.13.48; 1.14.13.49; 1.14.13.80; 1.14.99.38;
1.14.13.48; 1.14.13.49; 1.14.13.80; 1.14.99.38;
Protein crystallography data
The structure of Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules, PDB code: 5xxi
was solved by
K.Maekawa,
M.Adachi,
M.B.Shah,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 43.63 / 2.30 |
| Space group | I 2 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 74.571, 142.958, 161.420, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 20.4 / 26.9 |
Other elements in 5xxi:
The structure of Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules also contains other interesting chemical elements:
| Iron | (Fe) | 1 atom |
| Chlorine | (Cl) | 4 atoms |
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules
(pdb code 5xxi). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules, PDB code: 5xxi:
In total only one binding site of Potassium was determined in the Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules, PDB code: 5xxi:
Potassium binding site 1 out of 1 in 5xxi
Go back to
Potassium Binding Sites List in 5xxi
Potassium binding site 1 out
of 1 in the Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of Crystal Structure of CYP2C9 in Complex with Multiple Losartan Molecules within 5.0Å range:
|
Reference:
K.Maekawa,
M.Adachi,
Y.Matsuzawa,
Q.Zhang,
R.Kuroki,
Y.Saito,
M.B.Shah.
Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9 Biochemistry V. 56 5476 2017.
ISSN: ISSN 1520-4995
PubMed: 28972767
DOI: 10.1021/ACS.BIOCHEM.7B00795
Page generated: Mon Dec 14 00:13:48 2020
ISSN: ISSN 1520-4995
PubMed: 28972767
DOI: 10.1021/ACS.BIOCHEM.7B00795
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