Potassium in PDB 5vk6: Open Conformation of Kcsa Non-Inactivating E71A Mutant

The structure of Open Conformation of Kcsa Non-Inactivating E71A Mutant, PDB code: 5vk6 was solved by L.G.Cuello, E.Perozo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.09 / 2.25
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	156.544, 156.544, 74.618, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 21.3

The binding sites of Potassium atom in the Open Conformation of Kcsa Non-Inactivating E71A Mutant (pdb code 5vk6). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 7 binding sites of Potassium where determined in the Open Conformation of Kcsa Non-Inactivating E71A Mutant, PDB code: 5vk6:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7;

Potassium binding site 1 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2003 b:0.2 occ:0.25 O C:HOH2119 4.0 80.7 1.0

Potassium binding site 2 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2004 b:47.7 occ:0.25 OG1 C:THR75 2.9 40.8 1.0 O C:THR75 3.1 40.5 1.0 K C:K2005 3.4 42.7 0.2 CB C:THR75 3.4 43.1 1.0 C C:THR75 3.9 40.5 1.0 CA C:THR75 4.3 36.4 1.0 CG2 C:THR75 4.6 53.8 1.0 N C:VAL76 4.8 42.7 1.0

Potassium binding site 3 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2005 b:42.7 occ:0.25 O C:THR75 2.7 40.5 1.0 O C:VAL76 2.9 35.8 1.0 K C:K2006 3.2 41.3 0.2 K C:K2004 3.4 47.7 0.2 C C:VAL76 3.7 35.5 1.0 C C:THR75 3.9 40.5 1.0 CA C:VAL76 4.1 32.8 1.0 N C:VAL76 4.5 42.7 1.0 N C:GLY77 4.6 39.1 1.0 CA C:GLY77 4.9 37.6 1.0

Potassium binding site 4 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2006 b:41.3 occ:0.25 O C:GLY77 2.8 34.7 1.0 O C:VAL76 2.9 35.8 1.0 K C:K2005 3.2 42.7 0.2 K C:K2007 3.3 39.6 0.2 C C:GLY77 3.6 37.0 1.0 C C:VAL76 4.1 35.5 1.0 CA C:GLY77 4.1 37.6 1.0 N C:TYR78 4.5 34.7 1.0 N C:GLY77 4.6 39.1 1.0 CA C:TYR78 4.8 33.0 1.0

Potassium binding site 5 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2007 b:39.6 occ:0.25 O C:TYR78 2.9 32.0 1.0 O C:GLY77 3.1 34.7 1.0 K C:K2006 3.3 41.3 0.2 C C:TYR78 3.5 35.1 1.0 CA C:TYR78 4.1 33.0 1.0 C C:GLY77 4.2 37.0 1.0 N C:GLY79 4.3 30.5 1.0 K C:K2008 4.5 87.9 0.2 CA C:GLY79 4.6 28.1 1.0 N C:TYR78 4.7 34.7 1.0

Potassium binding site 6 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2008 b:87.9 occ:0.25 K C:K2009 2.9 63.6 0.2 O C:HOH2118 4.0 64.0 1.0 O C:TYR78 4.2 32.0 1.0 K C:K2007 4.5 39.6 0.2 O C:GLY79 4.7 32.4 1.0

Potassium binding site 7 out of 7 in the Open Conformation of Kcsa Non-Inactivating E71A Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of Open Conformation of Kcsa Non-Inactivating E71A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ C:K2009 b:63.6 occ:0.25 K C:K2008 2.9 87.9 0.2 O C:HOH2118 3.3 64.0 1.0

L.G.Cuello, D.M.Cortes, E.Perozo. The Gating Cycle of A K+ Channel at Atomic Resolution. Elife V. 6 2017.
ISSN: ESSN 2050-084X
PubMed: 29165243
DOI: 10.7554/ELIFE.28032