Potassium in PDB 5un7: Structure of the Human POT1-TPP1 Telomeric Complex

The structure of Structure of the Human POT1-TPP1 Telomeric Complex, PDB code: 5un7 was solved by C.Rice, T.Doukov, E.Skordalakes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	99.530, 99.530, 122.140, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 22.2

The structure of Structure of the Human POT1-TPP1 Telomeric Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Potassium atom in the Structure of the Human POT1-TPP1 Telomeric Complex (pdb code 5un7). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Structure of the Human POT1-TPP1 Telomeric Complex, PDB code: 5un7:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Structure of the Human POT1-TPP1 Telomeric Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of the Human POT1-TPP1 Telomeric Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:K701 b:52.3 occ:1.00 O A:HOH1167 2.6 37.4 1.0 O A:GLY551 2.6 36.2 1.0 C A:GLY551 3.6 31.8 1.0 CA A:GLY551 3.9 30.8 1.0 O A:HOH919 4.1 44.4 1.0 O A:HOH983 4.2 42.9 1.0 N A:THR552 4.8 32.0 1.0

Potassium binding site 2 out of 3 in the Structure of the Human POT1-TPP1 Telomeric Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of the Human POT1-TPP1 Telomeric Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:K702 b:42.7 occ:0.33 OG A:SER527 2.6 33.0 1.0 OG A:SER528 2.6 29.4 1.0 N A:SER528 3.1 28.4 1.0 C A:SER527 3.4 29.4 1.0 CA A:SER528 3.5 29.5 1.0 CB A:SER528 3.5 29.6 1.0 CB A:SER527 3.6 32.2 1.0 CG2 A:ILE525 3.9 35.1 1.0 CA A:SER527 4.0 29.9 1.0 O A:SER527 4.0 28.3 1.0 CB A:ILE525 4.1 33.1 1.0 N A:SER527 4.4 30.5 1.0 O A:HOH857 4.5 45.3 1.0 O A:ILE525 4.7 31.4 1.0 CD1 A:ILE525 4.7 34.0 1.0 O A:HOH810 4.8 36.8 1.0 C A:ILE525 5.0 33.1 1.0

Potassium binding site 3 out of 3 in the Structure of the Human POT1-TPP1 Telomeric Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of the Human POT1-TPP1 Telomeric Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:K703 b:53.2 occ:1.00 O A:ASP598 2.6 39.4 1.0 O A:HOH926 2.6 42.0 1.0 O A:HOH899 2.6 44.4 1.0 O A:HOH948 2.6 37.0 1.0 O A:HOH1169 2.6 50.6 1.0 C A:ASP598 3.6 36.7 1.0 CA A:ALA599 4.2 38.2 1.0 NZ A:LYS365 4.3 30.3 1.0 N A:ALA599 4.3 36.0 1.0 OD2 A:ASP598 4.5 42.5 1.0 O A:HOH988 4.6 50.6 1.0 O A:HOH1109 4.6 23.7 1.0 CA A:ASP598 4.7 36.7 1.0 O A:TYR600 4.7 34.2 1.0 C A:ALA599 4.8 37.8 1.0 O A:HOH1023 4.8 56.4 1.0 CB A:ASP598 4.9 37.7 1.0

C.Rice, P.K.Shastrula, A.V.Kossenkov, R.Hills, D.M.Baird, L.C.Showe, T.Doukov, S.Janicki, E.Skordalakes. Structural and Functional Analysis of the Human POT1-TPP1 Telomeric Complex. Nat Commun V. 8 14928 2017.
ISSN: ESSN 2041-1723
PubMed: 28393830
DOI: 10.1038/NCOMMS14928