Potassium in PDB 5u41: Human Ppardelta Ligand-Binding Domain in Complexed with Specific Agonist 16

The structure of Human Ppardelta Ligand-Binding Domain in Complexed with Specific Agonist 16, PDB code: 5u41 was solved by C.-C.Wu, T.J.Baiga, M.Downes, J.J.La Clair, A.R.Atkins, S.B.Richard, T.A.Stockley-Noel, M.E.Bowman, R.M.Evans, J.P.Noel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.60 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	39.449, 95.124, 95.795, 90.00, 96.44, 90.00
R / Rfree (%)	21 / 26.9

The binding sites of Potassium atom in the Human Ppardelta Ligand-Binding Domain in Complexed with Specific Agonist 16 (pdb code 5u41). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Human Ppardelta Ligand-Binding Domain in Complexed with Specific Agonist 16, PDB code: 5u41:

Potassium binding site 1 out of 1 in the Human Ppardelta Ligand-Binding Domain in Complexed with Specific Agonist 16


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Ppardelta Ligand-Binding Domain in Complexed with Specific Agonist 16 within 5.0Å range: probe atom residue distance (Å) B Occ B:K506 b:37.3 occ:1.00 HH22 B:ARG198 1.7 48.3 1.0 NH2 B:ARG198 2.4 40.2 1.0 HD22 B:ASN339 2.5 32.5 1.0 HH21 B:ARG198 2.8 48.3 1.0 HA B:ASN299 2.9 25.9 1.0 O B:HOH670 3.0 25.2 1.0 O B:HOH649 3.1 31.3 1.0 HB2 B:ASN339 3.3 29.3 1.0 ND2 B:ASN339 3.3 27.1 1.0 HH12 B:ARG198 3.4 39.2 1.0 HB3 B:ASN339 3.4 29.3 1.0 O B:VAL298 3.5 18.9 1.0 CZ B:ARG198 3.6 44.8 1.0 HB2 B:ASN299 3.6 43.2 1.0 HB3 B:ASN299 3.7 43.2 1.0 CB B:ASN339 3.7 24.4 1.0 CA B:ASN299 3.7 21.6 1.0 NH1 B:ARG198 3.8 32.7 1.0 HD21 B:ASN339 3.8 32.5 1.0 HA B:VAL336 3.9 26.4 1.0 CB B:ASN299 3.9 36.0 1.0 HG22 B:VAL336 3.9 34.1 1.0 CG B:ASN339 4.0 26.8 1.0 HG13 B:VAL336 4.0 60.2 1.0 H B:LYS300 4.3 28.3 1.0 C B:VAL298 4.4 22.6 1.0 N B:ASN299 4.6 19.4 1.0 HH11 B:ARG198 4.7 39.2 1.0 C B:ASN299 4.7 21.9 1.0 NE B:ARG198 4.7 41.3 1.0 N B:LYS300 4.8 23.6 1.0 CA B:VAL336 4.8 22.0 1.0 CG2 B:VAL336 4.8 28.4 1.0 HE B:ARG198 4.9 49.5 1.0 CG1 B:VAL336 4.9 50.1 1.0

C.C.Wu, T.J.Baiga, M.Downes, J.J.La Clair, A.R.Atkins, S.B.Richard, W.Fan, T.A.Stockley-Noel, M.E.Bowman, J.P.Noel, R.M.Evans. Structural Basis For Specific Ligation of the Peroxisome Proliferator-Activated Receptor Delta. Proc. Natl. Acad. Sci. V. 114 E2563 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 28320959
DOI: 10.1073/PNAS.1621513114