Atomistry » Potassium » PDB 5sc8-5u3q » 5top
Atomistry »
  Potassium »
    PDB 5sc8-5u3q »
      5top »

Potassium in PDB 5top: Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase

Enzymatic activity of Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase

All present enzymatic activity of Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase:
3.5.2.6;

Protein crystallography data

The structure of Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase, PDB code: 5top was solved by E.M.Lewandowski, Y.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.18
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 45.093, 106.821, 47.933, 90.00, 101.66, 90.00
R / Rfree (%) 12.8 / 14.6

Other elements in 5top:

The structure of Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase also contains other interesting chemical elements:

Ruthenium (Ru) 8 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase (pdb code 5top). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase, PDB code: 5top:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 5top

Go back to Potassium Binding Sites List in 5top
Potassium binding site 1 out of 2 in the Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K301

b:16.4
occ:1.00
 O A:GLY238 2.7 12.1 1.0
O A:HOH546 2.7 27.1 1.0
O A:HOH442 2.7 16.7 1.0
O A:HOH488 2.7 15.4 1.0
O A:HOH467 2.9 15.0 1.0
O A:HOH554 3.0 23.2 1.0
C A:GLY238 3.6 11.8 1.0
O A:ALA272 4.2 14.9 1.0
N A:ASP240 4.3 12.0 1.0
CA A:ASP240 4.3 12.3 1.0
CA A:GLY242 4.4 12.2 1.0
N A:GLY242 4.4 11.9 1.0
CA A:GLY238 4.4 11.7 1.0
N A:GLY238 4.5 11.7 1.0
OG A:SER274 4.5 15.7 0.7
O28 A:JSE302 4.6 20.5 1.0
C A:ASP240 4.8 11.7 1.0
O A:HOH564 4.8 27.3 1.0
N A:THR243 4.9 11.4 1.0
OD1 A:ASP240 4.9 16.0 1.0
O A:HOH435 4.9 27.6 1.0
C A:GLY242 5.0 11.8 1.0

Potassium binding site 2 out of 2 in 5top

Go back to Potassium Binding Sites List in 5top
Potassium binding site 2 out of 2 in the Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Atomic Resolution X-Ray Crystal Structure of A Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with Ctx-M-14 S70G Beta-Lactamase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K301

b:20.4
occ:1.00
 O B:GLY238 2.6 14.7 1.0
O B:HOH472 2.7 19.0 1.0
O B:HOH481 2.7 29.2 1.0
O B:HOH437 2.8 21.2 1.0
O B:HOH447 2.9 19.3 1.0
O B:HOH578 2.9 19.7 0.5
C B:GLY238 3.6 14.4 1.0
O B:ALA272 4.1 18.7 1.0
N B:ASP240 4.3 15.6 1.0
CA B:ASP240 4.3 16.0 1.0
CA B:GLY242 4.4 15.1 1.0
N B:GLY242 4.4 15.1 1.0
CA B:GLY238 4.4 14.3 1.0
N B:GLY238 4.4 13.7 1.0
O28 B:JSE302 4.5 23.9 1.0
OG B:SER274 4.5 21.1 1.0
C B:ASP240 4.8 15.7 1.0
N B:THR243 4.9 13.8 1.0
O B:HOH448 4.9 39.6 1.0
OD1 B:ASP240 4.9 20.0 1.0
C B:GLY242 4.9 14.1 1.0

Reference:

E.M.Lewandowski, K.G.Lethbridge, R.Sanishvili, J.Skiba, K.Kowalski, Y.Chen. Mechanisms of Proton Relay and Product Release By Class A Beta-Lactamase at Ultrahigh Resolution. Febs J. V. 285 87 2018.
ISSN: ISSN 1742-4658
PubMed: 29095570
DOI: 10.1111/FEBS.14315
Page generated: Mon Aug 12 14:38:27 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy