Potassium in PDB 5i2v: uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region

The binding sites of Potassium atom in the uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region (pdb code 5i2v). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region, PDB code: 5i2v:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region within 5.0Å range: probe atom residue distance (Å) B Occ A:K101 b:0.0 occ:1.00 O6 A:DG6 2.6 0.0 1.0 O6 A:DG18 2.6 0.0 1.0 O6 A:DG19 2.7 0.0 1.0 O6 A:DG2 2.7 0.0 1.0 O6 A:DG11 2.7 0.0 1.0 O6 A:DG12 2.7 0.0 1.0 O6 A:DG3 2.7 0.0 1.0 O6 A:DG7 2.8 0.0 1.0 H1 A:DG6 3.3 0.0 1.0 H1 A:DG11 3.3 0.0 1.0 H1 A:DG18 3.4 0.0 1.0 H1 A:DG2 3.4 0.0 1.0 C6 A:DG18 3.6 0.0 1.0 C6 A:DG6 3.6 0.0 1.0 C6 A:DG11 3.6 0.0 1.0 K A:K102 3.6 0.0 1.0 C6 A:DG19 3.7 0.0 1.0 C6 A:DG3 3.7 0.0 1.0 C6 A:DG2 3.7 0.0 1.0 C6 A:DG7 3.7 0.0 1.0 H1 A:DG3 3.7 0.0 1.0 H1 A:DG19 3.7 0.0 1.0 C6 A:DG12 3.8 0.0 1.0 N1 A:DG11 3.8 0.0 1.0 H1 A:DG7 3.8 0.0 1.0 N1 A:DG6 3.8 0.0 1.0 N1 A:DG18 3.9 0.0 1.0 H1 A:DG12 3.9 0.0 1.0 N1 A:DG2 3.9 0.0 1.0 N1 A:DG3 4.1 0.0 1.0 N1 A:DG19 4.1 0.0 1.0 N1 A:DG7 4.1 0.0 1.0 N1 A:DG12 4.3 0.0 1.0 C5 A:DG7 4.8 0.0 1.0 C5 A:DG18 4.8 0.0 1.0 C5 A:DG19 4.8 0.0 1.0 C5 A:DG3 4.8 0.0 1.0 C5 A:DG6 4.9 0.0 1.0 C5 A:DG11 4.9 0.0 1.0 C5 A:DG12 5.0 0.0 1.0 C5 A:DG2 5.0 0.0 1.0

Potassium binding site 2 out of 2 in the uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of uc(Nmr) Structure of A New G-Quadruplex Forming Sequence Within the Kras Proto-Oncogene Promoter Region within 5.0Å range: probe atom residue distance (Å) B Occ A:K102 b:0.0 occ:1.00 O6 A:DG9 2.7 0.0 1.0 O6 A:DG4 2.7 0.0 1.0 O6 A:DG13 2.7 0.0 1.0 O6 A:DG19 2.7 0.0 1.0 O6 A:DG3 2.7 0.0 1.0 O6 A:DG20 2.7 0.0 1.0 O6 A:DG12 2.8 0.0 1.0 O6 A:DG7 2.8 0.0 1.0 H1 A:DG4 3.3 0.0 1.0 H1 A:DG13 3.3 0.0 1.0 H1 A:DG20 3.5 0.0 1.0 C6 A:DG12 3.6 0.0 1.0 C6 A:DG19 3.6 0.0 1.0 C6 A:DG4 3.6 0.0 1.0 K A:K101 3.6 0.0 1.0 H1 A:DG9 3.6 0.0 1.0 C6 A:DG13 3.6 0.0 1.0 C6 A:DG3 3.6 0.0 1.0 C6 A:DG9 3.7 0.0 1.0 H62 A:DA22 3.7 0.0 1.0 H1 A:DG3 3.7 0.0 1.0 C6 A:DG20 3.7 0.0 1.0 H1 A:DG12 3.8 0.0 1.0 H1 A:DG19 3.8 0.0 1.0 H1 A:DG7 3.8 0.0 1.0 C6 A:DG7 3.8 0.0 1.0 N1 A:DG4 3.8 0.0 1.0 N1 A:DG13 3.9 0.0 1.0 N1 A:DG12 4.0 0.0 1.0 N1 A:DG20 4.0 0.0 1.0 N1 A:DG19 4.1 0.0 1.0 N1 A:DG3 4.1 0.0 1.0 N1 A:DG9 4.1 0.0 1.0 N1 A:DG7 4.2 0.0 1.0 C5 A:DG12 4.6 0.0 1.0 N6 A:DA22 4.6 0.0 1.0 C5 A:DG19 4.6 0.0 1.0 C5 A:DG3 4.8 0.0 1.0 H61 A:DA22 4.9 0.0 1.0 C5 A:DG4 4.9 0.0 1.0 C5 A:DG9 4.9 0.0 1.0 C5 A:DG13 5.0 0.0 1.0 C5 A:DG7 5.0 0.0 1.0

A.Kerkour, J.Marquevielle, S.Ivashchenko, L.A.Yatsunyk, J.L.Mergny, G.F.Salgado. High-Resolution Three-Dimensional uc(Nmr) Structure of the Kras Proto-Oncogene Promoter Reveals Key Features of A G-Quadruplex Involved in Transcriptional Regulation. J. Biol. Chem. V. 292 8082 2017.
ISSN: ESSN 1083-351X
PubMed: 28330874
DOI: 10.1074/JBC.M117.781906