Potassium in PDB 5hv4: Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221

The structure of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221, PDB code: 5hv4 was solved by N.J.Schnicker, M.Dey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.37 / 2.35
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	42.551, 146.189, 75.075, 90.00, 90.00, 90.00
R / Rfree (%)	19.9 / 24.5

The structure of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 also contains other interesting chemical elements:

Cadmium

(Cd)

5 atoms

The binding sites of Potassium atom in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 (pdb code 5hv4). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221, PDB code: 5hv4:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 within 5.0Å range: probe atom residue distance (Å) B Occ A:K307 b:41.8 occ:1.00 OD2 A:ASP54 2.7 37.1 1.0 NZ A:LYS172 3.0 40.7 1.0 OD1 A:ASP54 3.2 33.7 1.0 CG A:ASP54 3.3 32.7 1.0 O A:HOH429 4.3 41.5 1.0 CE A:LYS172 4.4 31.0 1.0 O A:ASP50 4.7 29.4 1.0 CB A:ASP54 4.8 24.9 1.0 CB A:ASP50 4.9 34.7 1.0

Potassium binding site 2 out of 6 in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 within 5.0Å range: probe atom residue distance (Å) B Occ A:K308 b:58.4 occ:1.00 OG A:SER186 2.8 42.4 1.0 OD1 A:ASP184 2.8 31.4 1.0 OD2 A:ASP184 3.1 33.5 1.0 CG A:ASP184 3.3 25.7 1.0 CB A:SER186 3.7 20.9 1.0 N A:SER186 4.8 20.6 1.0 CB A:ASP184 4.8 22.2 1.0 CA A:SER186 4.9 24.2 1.0

Potassium binding site 3 out of 6 in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 within 5.0Å range: probe atom residue distance (Å) B Occ A:K309 b:33.3 occ:1.00 NE2 A:HIS114 2.5 29.6 1.0 CE1 A:HIS114 3.2 28.2 1.0 CD2 A:HIS114 3.5 34.0 1.0 ND1 A:HIS114 4.3 29.4 1.0 CG A:HIS114 4.5 27.8 1.0 N A:ALA84 4.6 42.1 1.0

Potassium binding site 4 out of 6 in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 within 5.0Å range: probe atom residue distance (Å) B Occ A:K310 b:52.0 occ:1.00 O A:HOH417 2.6 40.6 1.0 OE1 A:GLU119 2.8 48.2 1.0 OE1 A:GLU202 2.8 34.0 1.0 OE2 A:GLU119 3.5 45.1 1.0 CD A:GLU202 3.5 35.8 1.0 CD A:GLU119 3.5 44.0 1.0 OE2 A:GLU202 3.8 40.9 1.0 ND2 A:ASN117 4.3 36.7 1.0 CG A:GLU202 4.6 24.5 1.0 CB A:GLU202 4.7 23.9 1.0 OD1 A:ASN117 4.9 29.2 1.0 NE1 A:TRP204 5.0 26.0 1.0 CG A:GLU119 5.0 29.8 1.0

Potassium binding site 5 out of 6 in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 within 5.0Å range: probe atom residue distance (Å) B Occ A:K311 b:68.8 occ:1.00 OE1 A:GLU154 2.8 43.1 1.0 O A:HOH410 3.0 46.2 1.0 O A:HOH451 3.6 24.9 1.0 CD A:GLU154 3.7 45.2 1.0 OE2 A:GLU154 3.9 52.8 1.0 N A:GLY201 4.6 23.8 1.0 CA A:GLY201 4.8 23.2 1.0

Potassium binding site 6 out of 6 in the Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Crystal Structure of A Prolyl 4-Hydroxylase Complexed with Alpha- Ketoglutarate From the Pathogenic Bacterium Bacillus Anthracis in C2221 within 5.0Å range: probe atom residue distance (Å) B Occ A:K312 b:67.0 occ:1.00 ND1 A:HIS134 3.0 54.1 1.0 O A:HIS134 3.2 50.4 1.0 CB A:HIS134 3.4 49.8 1.0 CG A:HIS134 3.6 49.9 1.0 C A:HIS134 3.7 45.5 1.0 CE1 A:HIS134 4.1 52.5 1.0 CA A:HIS134 4.2 41.4 1.0 N A:SER135 4.4 45.2 1.0 CA A:SER135 4.8 32.4 1.0 CD2 A:HIS134 4.8 53.8 1.0 NE2 A:HIS134 5.0 51.7 1.0

N.J.Schnicker, M.Dey. Structural Analysis of Cofactor Binding For A Prolyl 4-Hydroxylase From the Pathogenic Bacterium Bacillus Anthracis. Acta Crystallogr D Struct V. 72 675 2016BIOL.
ISSN: ISSN 2059-7983
PubMed: 27139630
DOI: 10.1107/S2059798316004198