Atomistry » Potassium » PDB 5f6q-5g13 » 5fog
Atomistry »
  Potassium »
    PDB 5f6q-5g13 »
      5fog »

Potassium in PDB 5fog: Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA)

Enzymatic activity of Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA)

All present enzymatic activity of Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA):
6.1.1.4;

Protein crystallography data

The structure of Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA), PDB code: 5fog was solved by A.Palencia, R.J.Liu, M.Lukarska, J.Gut, A.Bougdour, B.Touquet, E.D.Wang, M.R.K.Alley, P.J.Rosenthal, M.A.Hakimi, S.Cusack, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 101.76 / 2.30
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 107.730, 107.730, 309.510, 90.00, 90.00, 90.00
R / Rfree (%) 20.087 / 23.607

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA) (pdb code 5fog). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA), PDB code: 5fog:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 5fog

Go back to Potassium Binding Sites List in 5fog
Potassium binding site 1 out of 2 in the Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1545

b:46.5
occ:1.00
 O C:HOH2046 2.6 30.5 1.0
O C:THR401 2.8 32.7 1.0
O C:ALA398 2.8 32.4 1.0
O C:HOH2049 3.0 43.8 1.0
O C:TYR403 3.1 31.1 1.0
O C:HOH2044 3.6 29.7 1.0
C C:THR401 3.9 31.9 1.0
C C:ALA398 4.0 31.3 1.0
CG2 C:THR401 4.0 34.3 1.0
C C:TYR403 4.1 28.9 1.0
N C:ALA398 4.3 28.6 1.0
O C:HOH2052 4.4 54.1 1.0
CA C:SER404 4.4 31.5 1.0
O C:SER404 4.5 30.2 1.0
N C:THR401 4.6 35.8 1.0
N C:SER404 4.6 30.2 1.0
CA C:THR401 4.7 33.4 1.0
CA C:ALA398 4.7 29.6 1.0
C C:PRO402 4.7 30.6 1.0
C C:SER404 4.7 30.8 1.0
N C:TYR403 4.8 29.8 1.0
OG C:SER397 4.8 34.2 1.0
N C:PRO402 4.9 29.6 1.0
CA C:PRO402 4.9 29.8 1.0
C C:PRO399 4.9 33.5 1.0
N C:MET400 4.9 35.8 1.0
N C:PRO399 4.9 34.3 1.0
CB C:THR401 5.0 34.4 1.0
CA C:PRO399 5.0 34.8 1.0

Potassium binding site 2 out of 2 in 5fog

Go back to Potassium Binding Sites List in 5fog
Potassium binding site 2 out of 2 in the Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Hte Cryptosporidium Muris Cytosolic Leucyl-Trna Synthetase Editing Domain Complex with A Post- Transfer Editing Analogue of Norvaline (NV2AA) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:K1543

b:40.3
occ:1.00
 O D:HOH2034 2.7 39.4 1.0
O D:THR401 2.7 33.1 1.0
O D:ALA398 2.8 29.6 1.0
O D:HOH2035 2.9 52.4 1.0
O D:HOH2038 2.9 43.4 1.0
O D:TYR403 2.9 34.9 1.0
O D:HOH2032 3.6 31.2 1.0
O D:HOH2037 3.7 54.6 1.0
C D:THR401 3.9 33.6 1.0
C D:TYR403 4.0 34.7 1.0
C D:ALA398 4.0 30.6 1.0
CG2 D:THR401 4.0 30.7 1.0
N D:ALA398 4.3 31.8 1.0
N D:THR401 4.5 34.6 1.0
O D:SER404 4.5 31.9 1.0
CA D:SER404 4.5 36.0 1.0
CA D:THR401 4.6 33.0 1.0
C D:PRO402 4.6 34.5 1.0
N D:SER404 4.7 35.1 1.0
N D:TYR403 4.7 34.1 1.0
CA D:ALA398 4.7 30.4 1.0
C D:SER404 4.8 33.2 1.0
N D:PRO402 4.9 34.4 1.0
O D:PRO402 4.9 36.0 1.0
CB D:THR401 4.9 31.9 1.0
C D:PRO399 4.9 34.3 1.0
N D:MET400 4.9 35.7 1.0
CA D:PRO402 4.9 34.1 1.0
OG D:SER397 5.0 34.1 1.0
CA D:TYR403 5.0 32.7 1.0
N D:PRO399 5.0 32.6 1.0

Reference:

A.Palencia, R.Liu, M.Lukarska, J.Gut, A.Bougdour, B.Touquet, E.Wang, X.Li, M.R.K.Alley, Y.R.Freund, P.J.Rosenthal, M.Hakimi, S.Cusack. Cryptosporidium and Toxoplasma Parasites Are Inhibited By A Benzoxaborole Targeting Leucyl-Trna Synthetase. Antimicrob.Agents Chemother. V. 60 5817 2016.
ISSN: ISSN 0066-4804
PubMed: 27431220
DOI: 10.1128/AAC.00873-16
Page generated: Mon Aug 12 13:34:34 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy