Potassium in PDB 5ec1: Kcsa with V76ESTER Mutation

The structure of Kcsa with V76ESTER Mutation, PDB code: 5ec1 was solved by K.Matulef, F.I.Valiyaveetil, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.78 / 2.75
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	155.600, 155.600, 75.640, 90.00, 90.00, 90.00
R / Rfree (%)	24.4 / 26.8

The binding sites of Potassium atom in the Kcsa with V76ESTER Mutation (pdb code 5ec1). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Kcsa with V76ESTER Mutation, PDB code: 5ec1:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in the Kcsa with V76ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Kcsa with V76ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K2003 b:30.0 occ:0.25 O C:TYR78 2.5 1.7 1.0 O C:GLY77 3.1 13.1 1.0 C C:TYR78 3.3 0.6 1.0 K C:K2004 4.0 30.0 0.2 CA C:TYR78 4.0 0.6 1.0 C C:GLY77 4.2 14.6 1.0 N C:GLY79 4.2 1.1 1.0 K C:K2007 4.4 30.0 0.2 CA C:GLY79 4.5 0.3 1.0 N C:TYR78 4.6 1.7 1.0

Potassium binding site 2 out of 6 in the Kcsa with V76ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Kcsa with V76ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K2004 b:30.0 occ:0.25 O C:LHV76 2.5 7.3 1.0 O C:GLY77 2.9 13.1 1.0 C C:LHV76 3.7 8.0 1.0 C C:GLY77 3.8 14.6 1.0 K C:K2003 4.0 30.0 0.2 CA C:GLY77 4.2 14.1 1.0 N C:GLY77 4.4 13.8 1.0 O C:THR75 4.5 8.7 1.0 CA C:LHV76 4.8 8.0 1.0 N C:TYR78 4.8 1.7 1.0

Potassium binding site 3 out of 6 in the Kcsa with V76ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Kcsa with V76ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K2005 b:30.0 occ:0.25 OG1 C:THR75 2.8 10.0 1.0 O C:THR75 3.2 8.7 1.0 CB C:THR75 3.5 8.2 1.0 C C:THR75 4.0 8.0 1.0 CA C:THR75 4.4 8.0 1.0 CG2 C:THR75 4.7 8.8 1.0 O C:THR74 4.8 3.8 1.0 OE C:LHV76 4.9 8.5 1.0

Potassium binding site 4 out of 6 in the Kcsa with V76ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Kcsa with V76ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K2006 b:30.0 occ:0.25 O C:HOH2103 4.1 37.0 1.0 O C:HOH2104 4.2 30.0 1.0

Potassium binding site 5 out of 6 in the Kcsa with V76ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Kcsa with V76ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K2007 b:30.0 occ:0.25 K C:K2008 3.0 30.0 0.2 O C:TYR78 4.0 1.7 1.0 K C:K2003 4.4 30.0 0.2 CA C:GLY79 4.6 0.3 1.0 O C:HOH2105 4.7 30.0 1.0

Potassium binding site 6 out of 6 in the Kcsa with V76ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Kcsa with V76ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K2008 b:30.0 occ:0.25 K C:K2007 3.0 30.0 0.2 O C:HOH2105 3.3 30.0 1.0

K.Matulef, A.W.Annen, J.C.Nix, F.I.Valiyaveetil. Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-Type Inactivation and in Recovery From Inactivation. Structure V. 24 750 2016.
ISSN: ISSN 0969-2126
PubMed: 27150040
DOI: 10.1016/J.STR.2016.02.021