Potassium in PDB 5ebw: Kcsa with G77ESTER Mutation

The structure of Kcsa with G77ESTER Mutation, PDB code: 5ebw was solved by K.Matulef, F.I.Valiyaveetil, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.23 / 2.30
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	156.910, 156.910, 75.837, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 24.9

The binding sites of Potassium atom in the Kcsa with G77ESTER Mutation (pdb code 5ebw). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Kcsa with G77ESTER Mutation, PDB code: 5ebw:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in the Kcsa with G77ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Kcsa with G77ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K1002 b:34.9 occ:0.25 O C:TYR78 2.9 20.8 1.0 O11 C:GOA77 3.0 26.5 1.0 K C:K1003 3.2 50.0 0.2 C C:TYR78 3.5 31.3 1.0 C1 C:GOA77 4.1 26.7 1.0 CA C:TYR78 4.2 30.0 1.0 N C:GLY79 4.3 26.2 1.0 K C:K1007 4.3 65.8 0.2 CA C:GLY79 4.5 22.1 1.0 N C:TYR78 4.6 24.2 1.0

Potassium binding site 2 out of 6 in the Kcsa with G77ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Kcsa with G77ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K1003 b:50.0 occ:0.25 K C:K1004 2.7 30.5 0.2 O C:VAL76 2.8 19.8 1.0 O11 C:GOA77 2.8 26.5 1.0 K C:K1002 3.2 34.9 0.2 C1 C:GOA77 3.7 26.7 1.0 C C:VAL76 3.9 29.6 1.0 C2 C:GOA77 4.2 32.6 1.0 O2 C:GOA77 4.5 28.1 1.0 N C:TYR78 4.6 24.2 1.0 O C:THR75 4.9 28.7 1.0 CA C:TYR78 5.0 30.0 1.0

Potassium binding site 3 out of 6 in the Kcsa with G77ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Kcsa with G77ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K1004 b:30.5 occ:0.25 K C:K1003 2.7 50.0 0.2 O C:THR75 2.8 28.7 1.0 O C:VAL76 2.8 19.8 1.0 K C:K1005 3.5 34.6 0.2 C C:VAL76 3.6 29.6 1.0 C C:THR75 3.9 24.8 1.0 CA C:VAL76 4.0 27.3 1.0 N C:VAL76 4.5 26.7 1.0 O2 C:GOA77 4.6 28.1 1.0 O11 C:GOA77 4.9 26.5 1.0 C2 C:GOA77 4.9 32.6 1.0

Potassium binding site 4 out of 6 in the Kcsa with G77ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Kcsa with G77ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K1005 b:34.6 occ:0.25 OG1 C:THR75 2.8 28.4 1.0 O C:THR75 3.0 28.7 1.0 K C:K1004 3.5 30.5 0.2 CB C:THR75 3.5 24.3 1.0 C C:THR75 3.8 24.8 1.0 CA C:THR75 4.3 26.6 1.0 N C:VAL76 4.7 26.7 1.0 O C:THR74 4.7 25.0 1.0 CG2 C:THR75 4.8 27.1 1.0

Potassium binding site 5 out of 6 in the Kcsa with G77ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Kcsa with G77ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K1006 b:45.2 occ:0.25 O C:HOH1127 3.5 30.0 1.0 O C:HOH1125 4.0 30.0 1.0

Potassium binding site 6 out of 6 in the Kcsa with G77ESTER Mutation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Kcsa with G77ESTER Mutation within 5.0Å range: probe atom residue distance (Å) B Occ C:K1007 b:65.8 occ:0.25 O C:TYR78 3.9 20.8 1.0 K C:K1002 4.3 34.9 0.2 CA C:GLY79 4.6 22.1 1.0 C C:TYR78 5.0 31.3 1.0 O C:GLY79 5.0 28.0 1.0

K.Matulef, A.W.Annen, J.C.Nix, F.I.Valiyaveetil. Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-Type Inactivation and in Recovery From Inactivation. Structure V. 24 750 2016.
ISSN: ISSN 0969-2126
PubMed: 27150040
DOI: 10.1016/J.STR.2016.02.021