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Potassium in PDB 5ebl: Kcsa T75G in the Conductive State

Protein crystallography data

The structure of Kcsa T75G in the Conductive State, PDB code: 5ebl was solved by K.Matulef, F.I.Valiyaveetil, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.85 / 2.30
Space group I 4
Cell size a, b, c (Å), α, β, γ (°) 155.410, 155.410, 76.273, 90.00, 90.00, 90.00
R / Rfree (%) 20.5 / 24.2

Potassium Binding Sites:

The binding sites of Potassium atom in the Kcsa T75G in the Conductive State (pdb code 5ebl). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the Kcsa T75G in the Conductive State, PDB code: 5ebl:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in 5ebl

Go back to Potassium Binding Sites List in 5ebl
Potassium binding site 1 out of 6 in the Kcsa T75G in the Conductive State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Kcsa T75G in the Conductive State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1002

b:35.1
occ:0.25
O C:TYR78 3.1 25.5 1.0
O C:GLY77 3.2 45.1 1.0
K C:K1003 3.6 34.4 0.2
C C:TYR78 3.6 27.7 1.0
N C:GLY79 4.2 21.7 1.0
CA C:TYR78 4.3 32.3 1.0
C C:GLY77 4.3 42.4 1.0
CA C:GLY79 4.4 21.4 1.0
K C:K1006 4.5 57.4 0.2
N C:TYR78 4.8 34.1 1.0

Potassium binding site 2 out of 6 in 5ebl

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Potassium binding site 2 out of 6 in the Kcsa T75G in the Conductive State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Kcsa T75G in the Conductive State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1003

b:34.4
occ:0.25
O C:VAL76 2.9 28.8 1.0
O C:GLY77 2.9 45.1 1.0
K C:K1004 3.2 38.3 0.2
K C:K1002 3.6 35.1 0.2
C C:GLY77 3.8 42.4 1.0
C C:VAL76 4.0 42.4 1.0
CA C:GLY77 4.3 44.2 1.0
N C:GLY77 4.6 37.5 1.0
O C:GLY75 4.8 37.0 1.0
N C:TYR78 4.8 34.1 1.0

Potassium binding site 3 out of 6 in 5ebl

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Potassium binding site 3 out of 6 in the Kcsa T75G in the Conductive State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Kcsa T75G in the Conductive State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1004

b:38.3
occ:0.25
O C:GLY75 2.6 37.0 1.0
K C:K1003 3.2 34.4 0.2
O C:VAL76 3.3 28.8 1.0
C C:GLY75 3.8 28.6 1.0
C C:VAL76 3.9 42.4 1.0
CA C:VAL76 4.2 27.9 1.0
N C:VAL76 4.5 25.5 1.0
K C:K1005 4.5 80.2 0.2
N C:GLY77 4.9 37.5 1.0
CA C:GLY75 4.9 26.5 1.0

Potassium binding site 4 out of 6 in 5ebl

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Potassium binding site 4 out of 6 in the Kcsa T75G in the Conductive State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Kcsa T75G in the Conductive State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1005

b:80.2
occ:0.25
O C:GLY75 4.3 37.0 1.0
K C:K1004 4.5 38.3 0.2
O C:HOH1119 4.8 44.0 1.0
C C:GLY75 4.8 28.6 1.0
CA C:GLY75 4.9 26.5 1.0
O C:THR74 5.0 25.1 1.0

Potassium binding site 5 out of 6 in 5ebl

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Potassium binding site 5 out of 6 in the Kcsa T75G in the Conductive State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Kcsa T75G in the Conductive State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1006

b:57.4
occ:0.25
O C:HOH1118 2.8 43.1 1.0
K C:K1007 2.9 76.6 0.2
O C:TYR78 4.3 25.5 1.0
K C:K1002 4.5 35.1 0.2
O C:GLY79 4.8 31.2 1.0
CA C:GLY79 4.9 21.4 1.0

Potassium binding site 6 out of 6 in 5ebl

Go back to Potassium Binding Sites List in 5ebl
Potassium binding site 6 out of 6 in the Kcsa T75G in the Conductive State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Kcsa T75G in the Conductive State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K1007

b:76.6
occ:0.25
K C:K1006 2.9 57.4 0.2
O C:HOH1118 3.5 43.1 1.0

Reference:

K.Matulef, A.W.Annen, J.C.Nix, F.I.Valiyaveetil. Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-Type Inactivation and in Recovery From Inactivation. Structure V. 24 750 2016.
ISSN: ISSN 0969-2126
PubMed: 27150040
DOI: 10.1016/J.STR.2016.02.021
Page generated: Mon Aug 12 13:20:35 2024

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