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Atomistry » Potassium » PDB 5cbv-5dea » 5dc6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Potassium » PDB 5cbv-5dea » 5dc6 » |
Potassium in PDB 5dc6: Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide SubstrateEnzymatic activity of Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate
All present enzymatic activity of Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate:
3.5.1.98; Protein crystallography data
The structure of Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate, PDB code: 5dc6
was solved by
C.Decroos,
M.S.Lee,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5dc6:
The structure of Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate also contains other interesting chemical elements:
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate
(pdb code 5dc6). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate, PDB code: 5dc6: Jump to Potassium binding site number: 1; 2; Potassium binding site 1 out of 2 in 5dc6Go back to Potassium Binding Sites List in 5dc6
Potassium binding site 1 out
of 2 in the Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate
Mono view Stereo pair view
Potassium binding site 2 out of 2 in 5dc6Go back to Potassium Binding Sites List in 5dc6
Potassium binding site 2 out
of 2 in the Crystal Structure of D176N-Y306F HDAC8 in Complex with A Tetrapeptide Substrate
Mono view Stereo pair view
Reference:
S.M.Gantt,
C.Decroos,
M.S.Lee,
L.E.Gullett,
C.M.Bowman,
D.W.Christianson,
C.A.Fierke.
General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry V. 55 820 2016.
Page generated: Mon Aug 12 13:12:46 2024
ISSN: ISSN 0006-2960 PubMed: 26806311 DOI: 10.1021/ACS.BIOCHEM.5B01327 |
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