Potassium in PDB 5ccq: Human Cyclophilin D Complexed with Inhibitor

All present enzymatic activity of Human Cyclophilin D Complexed with Inhibitor:
5.2.1.8;

The structure of Human Cyclophilin D Complexed with Inhibitor, PDB code: 5ccq was solved by R.P.Gibson, E.Shore, N.Kershaw, M.Awais, A.Javed, D.Latawiec, S.Pandalaneni, L.Wen, N.Berry, P.O'neill, R.Sutton, L.Y.Lian, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.20 / 1.80
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.460, 57.460, 113.860, 90.00, 90.00, 90.00
R / Rfree (%)	16.4 / 20.3

The binding sites of Potassium atom in the Human Cyclophilin D Complexed with Inhibitor (pdb code 5ccq). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Cyclophilin D Complexed with Inhibitor, PDB code: 5ccq:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Human Cyclophilin D Complexed with Inhibitor


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Cyclophilin D Complexed with Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:22.6 occ:0.50 O2 A:PGE205 2.6 27.1 1.0 O3 A:PGE205 2.9 28.2 1.0 O4 A:PGE205 3.0 37.3 1.0 O1 A:PGE205 3.1 23.2 1.0 C2 A:PGE205 3.5 24.2 1.0 C1 A:PGE205 3.5 26.3 1.0 C3 A:PGE205 3.7 29.0 1.0 C4 A:PGE205 3.7 31.1 1.0 C6 A:PGE205 3.8 34.8 1.0 C5 A:PGE205 3.8 34.1 1.0

Potassium binding site 2 out of 2 in the Human Cyclophilin D Complexed with Inhibitor


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Cyclophilin D Complexed with Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:K202 b:35.6 occ:1.00 O A:CYS161 2.7 15.5 1.0 O A:HOH420 2.8 37.3 1.0 O1 A:FMT203 2.8 39.1 1.0 OD1 A:ASP160 2.9 21.0 1.0 OH A:TYR7 3.2 19.1 1.0 C A:FMT203 3.6 32.4 1.0 CG A:ASP160 3.7 24.1 1.0 O A:HOH367 3.7 34.9 1.0 C A:CYS161 3.8 12.5 1.0 OD2 A:ASP160 3.8 29.5 1.0 O A:HOH343 3.8 28.8 1.0 CZ A:TYR7 4.3 16.1 1.0 N A:CYS161 4.3 12.7 1.0 CA A:GLY162 4.5 12.7 1.0 N A:GLY162 4.6 11.8 1.0 O A:HOH407 4.6 19.5 1.0 NZ A:LYS49 4.7 31.1 1.0 CA A:CYS161 4.7 13.2 1.0 O2 A:FMT203 4.9 32.7 1.0 CE2 A:TYR7 4.9 15.1 1.0

R.P.Gibson, E.Shore, N.Kershaw, M.Awais, A.Javed, D.Latawiec, S.Pandalaneni, L.Wen, N.Berry, P.O'neill, R.Sutton, L.Y.Lian. Human Cyclophilin D Complexed with Inhibitor To Be Published.