Potassium in PDB 5cbw: Human Cyclophilin D Complexed with Inhibitor.

All present enzymatic activity of Human Cyclophilin D Complexed with Inhibitor.:
5.2.1.8;

The structure of Human Cyclophilin D Complexed with Inhibitor., PDB code: 5cbw was solved by R.P.Gibson, E.Shore, N.Kershaw, M.Awais, A.Javed, D.Latawiec, S.Pandalaneni, L.Wen, N.Berry, P.O'neill, R.Sutton, L.Y.Lian, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.18 / 1.80
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.265, 57.265, 114.502, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 20.8

The binding sites of Potassium atom in the Human Cyclophilin D Complexed with Inhibitor. (pdb code 5cbw). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Cyclophilin D Complexed with Inhibitor., PDB code: 5cbw:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Human Cyclophilin D Complexed with Inhibitor.


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Cyclophilin D Complexed with Inhibitor. within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:30.6 occ:0.50 O2 A:PGE205 2.7 37.6 1.0 O3 A:PGE205 2.9 35.5 1.0 O4 A:PGE205 2.9 43.6 1.0 O1 A:PGE205 3.4 37.7 1.0 C3 A:PGE205 3.7 37.0 1.0 C4 A:PGE205 3.7 36.5 1.0 C2 A:PGE205 3.7 38.9 1.0 C1 A:PGE205 3.8 40.7 1.0 C5 A:PGE205 3.8 40.2 1.0 C6 A:PGE205 3.9 41.2 1.0

Potassium binding site 2 out of 2 in the Human Cyclophilin D Complexed with Inhibitor.


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Cyclophilin D Complexed with Inhibitor. within 5.0Å range: probe atom residue distance (Å) B Occ A:K202 b:37.0 occ:1.00 O A:CYS161 2.7 18.2 1.0 O A:HOH433 2.8 34.9 1.0 OD1 A:ASP160 2.9 24.0 1.0 O1 A:FMT203 2.9 44.5 1.0 OH A:TYR7 3.3 23.6 1.0 O A:HOH360 3.5 40.1 1.0 O A:HOH330 3.8 27.1 1.0 C A:FMT203 3.8 40.5 1.0 CG A:ASP160 3.8 25.9 1.0 C A:CYS161 3.8 16.5 1.0 OD2 A:ASP160 3.9 29.5 1.0 N A:CYS161 4.4 16.6 1.0 CZ A:TYR7 4.4 19.8 1.0 CA A:GLY162 4.5 17.1 1.0 N A:GLY162 4.6 16.9 1.0 O A:HOH395 4.6 23.5 1.0 CA A:CYS161 4.7 16.8 1.0 NZ A:LYS49 4.8 41.7 1.0

R.P.Gibson, E.Shore, N.Kershaw, M.Awais, A.Javed, D.Latawiec, S.Pandalaneni, L.Wen, N.Berry, P.O'neill, R.Sutton, L.Y.Lian. Human Cyclophilin D Complexed with Inhibitor. To Be Published.