Atomistry » Potassium » PDB 5avx-5cbu » 5byi
Atomistry »
  Potassium »
    PDB 5avx-5cbu »
      5byi »

Potassium in PDB 5byi: Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D)

Enzymatic activity of Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D)

All present enzymatic activity of Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D):
4.2.1.1;

Protein crystallography data

The structure of Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D), PDB code: 5byi was solved by M.Groll, J.Broichhagen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 10.00 / 1.15
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.050, 41.220, 71.930, 90.00, 104.23, 90.00
R / Rfree (%) 17.1 / 18.7

Other elements in 5byi:

The structure of Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D) also contains other interesting chemical elements:

Mercury (Hg) 1 atom
Zinc (Zn) 1 atom

Potassium Binding Sites:

The binding sites of Potassium atom in the Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D) (pdb code 5byi). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D), PDB code: 5byi:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 5byi

Go back to Potassium Binding Sites List in 5byi
Potassium binding site 1 out of 2 in the Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K304

b:11.4
occ:1.00
O A:HOH662 2.9 32.5 1.0
OE1 A:GLU238 3.3 24.1 1.0
CD A:GLU238 3.4 23.0 1.0
OE2 A:GLU238 3.5 27.8 1.0
CG A:GLU238 4.3 20.5 1.0
O A:HOH704 4.3 20.6 1.0
O A:HOH697 4.5 30.0 1.0
O A:HOH407 4.7 18.9 1.0
CA A:GLY8 5.0 16.0 1.0

Potassium binding site 2 out of 2 in 5byi

Go back to Potassium Binding Sites List in 5byi
Potassium binding site 2 out of 2 in the Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Carbonic Anhydrase II with An Azobenzene Inhibitor (1D) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K305

b:10.1
occ:1.00
ND1 A:HIS64 2.3 17.9 0.8
O A:HOH705 2.8 57.0 1.0
O A:HOH639 2.8 25.6 1.0
O A:ASN62 2.8 13.9 1.0
CE1 A:HIS64 3.2 18.0 1.0
CG A:HIS64 3.3 15.4 0.9
N A:HIS64 3.5 10.6 1.0
CB A:HIS64 3.6 12.2 1.0
C A:GLY63 3.7 11.4 1.0
C A:ASN62 3.8 11.2 1.0
CA A:GLY63 4.1 11.5 1.0
O A:GLY63 4.1 11.4 1.0
CA A:HIS64 4.1 10.1 1.0
OD1 A:ASN62 4.3 10.0 1.0
O A:HOH680 4.3 34.0 1.0
CZ2 A:TRP5 4.3 10.0 1.0
NE2 A:HIS64 4.4 20.5 0.9
N A:GLY63 4.4 11.9 1.0
CD2 A:HIS64 4.4 17.2 1.0
CG A:ASN62 4.7 10.4 1.0
CH2 A:TRP5 4.7 10.0 1.0
NZ A:LYS169 4.8 34.3 1.0
CE2 A:TRP5 4.8 9.5 1.0
CE A:LYS169 4.8 25.1 1.0
CB A:ASN62 4.8 12.1 1.0
O A:HOH590 4.9 14.9 1.0
CA A:ASN62 5.0 11.8 1.0

Reference:

L.S.Runtsch, D.M.Barber, P.Mayer, M.Groll, D.Trauner, J.Broichhagen. Azobenzene-Based Inhibitors of Human Carbonic Anhydrase II. Beilstein J Org Chem V. 11 1129 2015.
ISSN: ISSN 1860-5397
PubMed: 26199669
DOI: 10.3762/BJOC.11.127
Page generated: Sun Dec 13 23:55:13 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy