Atomistry » Potassium » PDB 4xs6-4zum » 4zqp
Atomistry »
  Potassium »
    PDB 4xs6-4zum »
      4zqp »

Potassium in PDB 4zqp: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1

Enzymatic activity of Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1

All present enzymatic activity of Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1:
1.1.1.205;

Protein crystallography data

The structure of Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1, PDB code: 4zqp was solved by Y.Kim, M.Makowska-Grzyska, M.Gu, M.Kavitha, L.Hedstrom, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.76 / 1.90
Space group I 4
Cell size a, b, c (Å), α, β, γ (°) 88.225, 88.225, 84.630, 90.00, 90.00, 90.00
R / Rfree (%) 14.3 / 18.9

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1 (pdb code 4zqp). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1, PDB code: 4zqp:

Potassium binding site 1 out of 1 in 4zqp

Go back to Potassium Binding Sites List in 4zqp
Potassium binding site 1 out of 1 in the Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Mycobacterium Tuberculosis in the Complex with Imp and the Inhibitor MAD1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K603

b:20.1
occ:1.00
O A:GLY338 2.7 18.9 1.0
O A:GLY336 2.8 19.9 1.0
O A:CYS341 2.9 17.2 1.0
O A:HOH769 3.2 20.9 1.0
CB A:CYS341 3.7 20.9 1.0
C A:CYS341 3.7 19.3 1.0
C A:GLY338 3.8 19.4 1.0
C A:PRO337 3.8 17.7 1.0
C A:GLY336 4.0 19.6 1.0
N A:GLY338 4.0 17.7 1.0
O A:PRO337 4.1 17.8 1.0
CA A:CYS341 4.1 18.9 1.0
N A:CYS341 4.2 18.7 1.0
CA A:PRO337 4.2 17.7 1.0
CA A:GLY338 4.5 16.1 1.0
SG A:CYS341 4.6 31.2 1.0
N A:PRO337 4.6 19.2 1.0
N A:THR342 4.8 18.9 1.0
N A:SER339 4.8 15.3 1.0
C A:SER339 4.9 16.8 1.0
CA A:SER339 5.0 15.7 1.0

Reference:

M.Makowska-Grzyska, Y.Kim, S.K.Gorla, Y.Wei, K.Mandapati, M.Zhang, N.Maltseva, G.Modi, H.I.Boshoff, M.Gu, C.Aldrich, G.D.Cuny, L.Hedstrom, A.Joachimiak. Mycobacterium Tuberculosis Impdh in Complexes with Substrates, Products and Antitubercular Compounds. Plos One V. 10 38976 2015.
ISSN: ESSN 1932-6203
PubMed: 26440283
DOI: 10.1371/JOURNAL.PONE.0138976
Page generated: Mon Aug 12 12:48:00 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy