Potassium in PDB 4zbm: Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant

The structure of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant, PDB code: 4zbm was solved by Y.Lam, W.Zeng, M.G.Derebe, Y.Jiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.90
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	67.907, 67.907, 89.799, 90.00, 90.00, 90.00
R / Rfree (%)	20.4 / 23.6

The structure of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant also contains other interesting chemical elements:

Barium

(Ba)

2 atoms

The binding sites of Potassium atom in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant (pdb code 4zbm). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 5 binding sites of Potassium where determined in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant, PDB code: 4zbm:
Jump to Potassium binding site number: 1; 2; 3; 4; 5;

Potassium binding site 1 out of 5 in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:10.1 occ:0.25 OG1 A:THR63 2.8 18.4 1.0 O A:HOH324 2.9 48.7 0.2 O A:THR63 2.9 18.2 1.0 CB A:THR63 3.4 21.7 1.0 C A:THR63 3.8 18.0 1.0 BA A:BA202 3.9 22.6 0.2 CA A:THR63 4.2 16.0 1.0 CG2 A:THR63 4.6 23.9 1.0 N A:VAL64 4.8 14.7 1.0 O A:THR62 5.0 21.1 1.0

Potassium binding site 2 out of 5 in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K203 b:36.0 occ:0.25 O A:HOH313 3.2 28.3 1.0 O A:VAL64 3.8 13.5 1.0 BA A:BA202 3.8 22.6 0.2 CA A:GLY65 4.0 17.1 1.0 K A:K204 4.5 62.5 0.2 C A:VAL64 4.7 19.6 1.0 N A:GLY65 4.9 16.8 1.0 N A:GLU66 4.9 16.9 1.0 C A:GLY65 5.0 16.4 1.0

Potassium binding site 3 out of 5 in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:K204 b:62.5 occ:0.25 O A:HOH312 3.5 16.6 1.0 O A:HOH316 3.6 46.7 1.0 O A:HOH313 3.7 28.3 1.0 K A:K203 4.5 36.0 0.2 OE2 A:GLU66 4.8 25.8 1.0 OG1 A:THR67 4.9 24.9 1.0

Potassium binding site 4 out of 5 in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:K202 b:18.7 occ:0.25 OG1 B:THR63 2.9 25.6 1.0 O B:THR63 3.0 26.2 1.0 O B:HOH318 3.2 65.3 0.2 CB B:THR63 3.4 28.2 1.0 C B:THR63 3.8 27.4 1.0 BA B:BA201 3.9 34.9 0.2 CA B:THR63 4.3 22.5 1.0 CG2 B:THR63 4.7 28.6 1.0 N B:VAL64 4.8 26.7 1.0 O B:THR62 5.0 23.8 1.0

Potassium binding site 5 out of 5 in the Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Crystal Structure of Drosophila Cyclic Nucleotide Gated Channel Pore Mimicking Nak Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:K203 b:66.1 occ:0.25 O B:HOH311 3.1 48.8 1.0 BA B:BA201 3.8 34.9 0.2 O B:VAL64 3.8 31.9 1.0 CA B:GLY65 3.9 32.2 1.0 C B:VAL64 4.7 32.3 1.0 N B:GLY65 4.9 29.6 1.0 N B:GLU66 4.9 37.6 1.0 C B:GLY65 5.0 35.4 1.0

Y.L.Lam, W.Zeng, M.G.Derebe, Y.Jiang. Structural Implications of Weak CA2+ Block in Drosophila Cyclic Nucleotide-Gated Channels. J.Gen.Physiol. V. 146 255 2015.
ISSN: ESSN 1540-7748
PubMed: 26283200
DOI: 10.1085/JGP.201511431