Potassium in PDB 4z49: Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution

All present enzymatic activity of Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution:
3.1.2.14;

The structure of Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution, PDB code: 4z49 was solved by G.Spraggon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.89 / 1.70
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	38.726, 117.591, 63.284, 90.00, 105.58, 90.00
R / Rfree (%)	17.1 / 21.2

The binding sites of Potassium atom in the Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution (pdb code 4z49). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution, PDB code: 4z49:

Potassium binding site 1 out of 1 in the Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:K2601 b:19.5 occ:1.00 O B:HOH2782 2.5 35.5 1.0 OG B:SER2308 3.0 16.1 1.0 N B:ILE2250 3.2 10.2 1.0 CB B:SER2308 3.3 12.4 1.0 N B:TYR2309 3.4 11.3 1.0 CB B:TYR2309 3.5 12.5 1.0 CG2 B:ILE2250 3.6 9.8 1.0 CB B:ILE2250 3.6 11.5 1.0 O B:HOH2783 3.7 34.2 1.0 CB B:PRO2249 3.7 12.2 1.0 CA B:ILE2250 4.0 10.2 1.0 CA B:PRO2249 4.0 9.9 1.0 CA B:TYR2309 4.0 11.7 1.0 C B:PRO2249 4.0 13.3 1.0 OE1 B:GLU2251 4.2 6.9 0.5 C B:SER2308 4.3 12.1 1.0 CA B:SER2308 4.4 9.8 1.0 O B:HOH2978 4.6 45.5 1.0 CG B:TYR2309 4.7 11.9 1.0 O B:HOH2895 4.9 34.9 1.0 O B:TYR2307 4.9 10.9 1.0 NE2 B:HIS2481 4.9 16.1 1.0 OE2 B:GLU2251 5.0 28.9 0.5 CD B:GLU2251 5.0 32.2 0.5 CD1 B:TYR2309 5.0 12.2 1.0 CG B:PRO2249 5.0 14.1 1.0

I.H.Park, J.D.Venable, C.Steckler, S.E.Cellitti, S.A.Lesley, G.Spraggon, A.Brock. Estimation of Hydrogen-Exchange Protection Factors From Md Simulation Based on Amide Hydrogen Bonding Analysis. J.Chem.Inf.Model. V. 55 1914 2015.
ISSN: ESSN 1549-960X
PubMed: 26241692
DOI: 10.1021/ACS.JCIM.5B00185