Potassium in PDB 4z0g: Structure of the Impdh From Ashbya Gossypii Bound to Gmp

All present enzymatic activity of Structure of the Impdh From Ashbya Gossypii Bound to Gmp:
1.1.1.205;

The structure of Structure of the Impdh From Ashbya Gossypii Bound to Gmp, PDB code: 4z0g was solved by R.M.Buey, J.M.De Pereda, J.L.Revuelta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.53 / 1.25
Space group	P 4
Cell size a, b, c (Å), α, β, γ (°)	117.480, 117.480, 56.525, 90.00, 90.00, 90.00
R / Rfree (%)	12.4 / 14.8

The binding sites of Potassium atom in the Structure of the Impdh From Ashbya Gossypii Bound to Gmp (pdb code 4z0g). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Structure of the Impdh From Ashbya Gossypii Bound to Gmp, PDB code: 4z0g:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Structure of the Impdh From Ashbya Gossypii Bound to Gmp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of the Impdh From Ashbya Gossypii Bound to Gmp within 5.0Å range: probe atom residue distance (Å) B Occ A:K602 b:13.8 occ:1.00 O A:GLY331 2.6 13.6 1.0 O A:GLY329 2.7 15.9 1.0 O A:CYS334 2.7 15.6 1.0 HB3 A:CYS334 3.1 20.6 1.0 H A:CYS334 3.5 16.3 1.0 C A:GLY331 3.7 12.7 1.0 O A:HOH843 3.7 15.6 1.0 C A:CYS334 3.8 14.3 1.0 C A:SER330 3.8 12.1 1.0 C A:GLY329 3.8 14.1 1.0 HA A:SER330 3.8 14.4 1.0 O A:SER330 3.9 13.6 1.0 CB A:CYS334 4.0 17.1 1.0 N A:GLY331 4.0 12.0 1.0 N A:CYS334 4.1 13.6 1.0 CA A:CYS334 4.2 14.5 1.0 CA A:SER330 4.2 12.0 1.0 H A:GLY331 4.3 14.4 1.0 HA A:SER332 4.3 15.9 1.0 CA A:GLY331 4.4 12.3 1.0 N A:SER330 4.4 12.2 1.0 HA A:ILE335 4.6 18.1 1.0 HB2 A:CYS334 4.6 20.6 1.0 N A:SER332 4.6 12.3 1.0 HA2 A:GLY329 4.7 17.2 1.0 C A:SER332 4.8 13.1 1.0 O A:SER332 4.8 14.8 1.0 CA A:SER332 4.8 13.2 1.0 CA A:GLY329 4.9 14.3 1.0 HA3 A:GLY331 4.9 14.8 1.0 SG A:CYS334 4.9 21.4 1.0 N A:ILE335 4.9 13.8 1.0

Potassium binding site 2 out of 2 in the Structure of the Impdh From Ashbya Gossypii Bound to Gmp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of the Impdh From Ashbya Gossypii Bound to Gmp within 5.0Å range: probe atom residue distance (Å) B Occ B:K602 b:13.8 occ:1.00 O B:GLY331 2.6 13.3 1.0 O B:GLY329 2.7 15.3 1.0 O B:CYS334 2.8 15.8 1.0 HB3 B:CYS334 3.1 22.4 1.0 H B:CYS334 3.5 16.7 1.0 C B:GLY331 3.7 11.6 1.0 O B:HOH801 3.7 15.6 1.0 C B:SER330 3.8 11.6 1.0 C B:CYS334 3.8 14.4 1.0 C B:GLY329 3.8 13.1 1.0 HA B:SER330 3.8 14.5 1.0 O B:SER330 3.9 13.8 1.0 N B:GLY331 4.0 12.4 1.0 CB B:CYS334 4.0 18.7 1.0 N B:CYS334 4.1 13.9 1.0 CA B:SER330 4.2 12.1 1.0 CA B:CYS334 4.2 14.8 1.0 H B:GLY331 4.2 14.9 1.0 HA B:SER332 4.3 15.7 1.0 N B:SER330 4.4 12.0 1.0 CA B:GLY331 4.4 13.3 1.0 HA B:ILE335 4.6 16.9 1.0 HB2 B:CYS334 4.6 22.4 1.0 N B:SER332 4.6 12.7 1.0 HA2 B:GLY329 4.7 17.9 1.0 C B:SER332 4.7 12.7 1.0 O B:SER332 4.8 14.7 1.0 CA B:SER332 4.8 13.0 1.0 CA B:GLY329 4.9 14.9 1.0 HA3 B:GLY331 4.9 16.0 1.0 N B:ILE335 4.9 14.3 1.0 SG B:CYS334 4.9 21.8 1.0

R.M.Buey, R.Ledesma-Amaro, A.Velazquez-Campoy, M.Balsera, M.Chagoyen, J.M.De Pereda, J.L.Revuelta. Guanine Nucleotide Binding to the Bateman Domain Mediates the Allosteric Inhibition of Eukaryotic Imp Dehydrogenases. Nat Commun V. 6 8923 2015.
ISSN: ESSN 2041-1723
PubMed: 26558346
DOI: 10.1038/NCOMMS9923