Potassium in PDB 4wpz: Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis

The structure of Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis, PDB code: 4wpz was solved by L.W.Kang, D.H.Kim, T.V.Pham, S.H.Han, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.54 / 2.10
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	114.877, 114.877, 79.049, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 24

The structure of Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Potassium atom in the Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis (pdb code 4wpz). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis, PDB code: 4wpz:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis within 5.0Å range: probe atom residue distance (Å) B Occ A:K501 b:32.1 occ:1.00 O A:HOH749 2.9 38.1 1.0 OG1 A:THR287 2.9 23.1 1.0 O A:HOH760 3.0 41.3 1.0 N A:PHE13 3.1 28.4 1.0 CD2 A:PHE13 3.6 33.1 1.0 CE1 A:PHE11 3.7 28.9 1.0 CB A:THR287 3.8 21.7 1.0 CB A:PHE13 3.8 34.3 1.0 CA A:PRO12 3.8 28.7 1.0 CB A:PRO12 3.9 29.1 1.0 C A:PRO12 3.9 28.2 1.0 CA A:PHE13 3.9 31.7 1.0 O A:PHE13 4.1 25.1 1.0 CG A:PHE13 4.1 37.0 1.0 CZ A:PHE11 4.1 26.2 1.0 O A:HOH759 4.2 34.1 1.0 CG A:PRO23 4.3 25.8 1.0 CD1 A:PHE11 4.4 29.6 1.0 CG2 A:THR287 4.4 25.0 1.0 C A:PHE13 4.4 29.7 1.0 CE2 A:PHE13 4.6 34.8 1.0 CE2 A:PHE11 5.0 26.8 1.0 O A:PRO12 5.0 28.2 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Cytochrome P450 CYP107W1 From Streptomyces Avermitilis within 5.0Å range: probe atom residue distance (Å) B Occ A:K502 b:17.8 occ:1.00 O A:HOH698 3.0 17.1 1.0 O A:HOH674 3.1 23.2 1.0 N A:LEU89 3.4 19.1 1.0 CA A:GLY235 3.8 17.1 1.0 CA A:SER88 4.0 21.9 1.0 CB A:LEU89 4.0 21.2 1.0 CD2 A:LEU232 4.0 30.6 1.0 CG A:LEU89 4.0 22.2 1.0 O A:ALA231 4.2 20.2 1.0 CD1 A:LEU89 4.2 22.7 1.0 C A:SER88 4.2 21.2 1.0 CA A:LEU232 4.2 19.6 1.0 CB A:SER88 4.2 25.3 1.0 C A:GLY235 4.3 17.1 1.0 O A:LEU232 4.3 19.9 1.0 O A:HOH741 4.3 30.1 1.0 CA A:LEU89 4.3 20.0 1.0 CMD A:HEM503 4.5 16.0 1.0 O A:HOH662 4.5 27.9 1.0 N A:GLY235 4.6 17.5 1.0 N A:ILE236 4.6 17.9 1.0 C A:LEU232 4.7 18.4 1.0 O A:GLY235 4.8 16.2 1.0 C A:ALA231 4.8 20.4 1.0 N A:LEU232 4.9 19.9 1.0

S.Han, T.V.Pham, J.H.Kim, Y.R.Lim, H.G.Park, G.S.Cha, C.H.Yun, Y.J.Chun, L.W.Kang, D.Kim. Functional Characterization of CYP107W1 From Streptomyces Avermitilis and Biosynthesis of Macrolide Oligomycin A. Arch.Biochem.Biophys. V. 575 1 2015.
ISSN: ESSN 1096-0384
PubMed: 25849761
DOI: 10.1016/J.ABB.2015.03.025