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Potassium in PDB 4r2c: EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna

Protein crystallography data

The structure of EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna, PDB code: 4r2c was solved by H.Hashimoto, Y.O.Olanrewaju, Y.Zheng, G.G.Wilson, X.Zhang, X.Cheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.04 / 1.89
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 43.977, 56.076, 129.605, 90.00, 90.00, 90.00
R / Rfree (%) 19.9 / 25

Other elements in 4r2c:

The structure of EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna also contains other interesting chemical elements:

Zinc (Zn) 3 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna (pdb code 4r2c). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna, PDB code: 4r2c:

Potassium binding site 1 out of 1 in 4r2c

Go back to Potassium Binding Sites List in 4r2c
Potassium binding site 1 out of 1 in the EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of EGR1/ZIF268 Zinc Fingers in Complex with Hydroxymethylated Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K504

b:62.7
occ:1.00
O A:VAL342 2.6 49.1 1.0
O A:CYS345 2.7 68.0 1.0
O A:CYS340 2.8 46.6 1.0
C A:VAL342 3.6 52.2 1.0
C A:CYS345 3.8 58.9 1.0
C A:CYS340 4.0 48.3 1.0
N A:VAL342 4.0 45.0 1.0
C A:PRO341 4.2 45.6 1.0
N A:GLU343 4.4 56.1 1.0
CA A:VAL342 4.4 50.0 1.0
CA A:ASP346 4.5 64.9 1.0
CA A:GLU343 4.5 65.3 1.0
CA A:PRO341 4.5 48.3 1.0
N A:ASP346 4.5 61.9 1.0
O A:GLU343 4.6 61.2 1.0
O A:PRO341 4.6 46.5 1.0
N A:PRO341 4.7 46.0 1.0
C A:GLU343 4.7 62.5 1.0
CA A:CYS345 4.8 58.3 1.0
N A:CYS345 4.8 66.2 1.0

Reference:

H.Hashimoto, Y.O.Olanrewaju, Y.Zheng, G.G.Wilson, X.Zhang, X.Cheng. Wilms Tumor Protein Recognizes 5-Carboxylcytosine Within A Specific Dna Sequence. Genes Dev. 2014.
ISSN: ISSN 0890-9369
PubMed: 25258363
DOI: 10.1101/GAD.250746.114
Page generated: Mon Aug 12 11:55:31 2024

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