Potassium in PDB 4qrh: Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp

All present enzymatic activity of Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp:
2.7.4.8;

The structure of Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp, PDB code: 4qrh was solved by K.Liu, K.Krasny, A.R.Myers, K.A.Satyshur, J.L.Keck, J.D.Wnag, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.26 / 1.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	69.486, 93.961, 85.259, 90.00, 111.09, 90.00
R / Rfree (%)	20.1 / 22.7

The structure of Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Potassium atom in the Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp (pdb code 4qrh). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp, PDB code: 4qrh:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp within 5.0Å range: probe atom residue distance (Å) B Occ B:K302 b:14.8 occ:1.00 O B:GLU103 2.7 13.2 1.0 O B:HOH411 2.8 19.6 1.0 O B:HOH410 2.8 12.7 1.0 OH B:TYR36 2.9 19.2 1.0 OG B:SER39 2.9 15.1 1.0 N7 B:0O2303 3.0 14.2 1.0 O B:HOH412 3.0 24.0 1.0 C8 B:0O2303 3.5 15.2 1.0 CB B:SER39 3.8 15.2 1.0 C5 B:0O2303 3.8 14.3 1.0 C B:GLU103 3.9 13.8 1.0 CZ B:TYR36 3.9 17.9 1.0 OE1 B:GLU103 4.1 19.6 1.0 O B:HOH409 4.3 12.6 1.0 O6 B:0O2303 4.3 14.2 1.0 O B:SER37 4.4 14.8 1.0 CE1 B:TYR36 4.4 17.0 1.0 N B:GLU103 4.4 13.2 1.0 O B:HOH413 4.4 27.1 1.0 CB B:GLU103 4.4 15.2 1.0 C6 B:0O2303 4.5 13.9 1.0 CA B:GLU103 4.5 14.0 1.0 CE1 B:TYR55 4.5 19.1 1.0 CD B:GLU103 4.5 18.1 1.0 N9 B:0O2303 4.5 15.7 1.0 N B:SER39 4.6 15.3 1.0 C4 B:0O2303 4.7 14.3 1.0 CG2 B:ILE104 4.8 14.2 1.0 CA B:SER39 4.8 15.3 1.0 OH B:TYR55 4.8 19.1 1.0 CE2 B:TYR36 4.9 17.4 1.0 N B:ILE104 5.0 13.8 1.0 CZ B:TYR55 5.0 19.3 1.0

Potassium binding site 2 out of 3 in the Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp within 5.0Å range: probe atom residue distance (Å) B Occ C:K302 b:15.6 occ:1.00 O C:GLU103 2.7 14.4 1.0 O C:HOH423 2.8 20.4 1.0 OG C:SER39 2.8 15.6 1.0 OH C:TYR36 2.8 19.6 1.0 O C:HOH422 2.9 15.2 1.0 N7 C:0O2304 3.0 14.5 1.0 O C:HOH424 3.2 22.6 1.0 C8 C:0O2304 3.6 14.8 1.0 CB C:SER39 3.7 15.9 1.0 C C:GLU103 3.8 14.6 1.0 C5 C:0O2304 3.8 14.4 1.0 CZ C:TYR36 3.9 18.1 1.0 OE1 C:GLU103 4.0 18.9 1.0 O C:SER37 4.3 16.1 1.0 O6 C:0O2304 4.3 15.2 1.0 O C:HOH421 4.3 15.3 1.0 N C:GLU103 4.3 14.8 1.0 CB C:GLU103 4.4 15.7 1.0 CD C:GLU103 4.4 17.6 1.0 O C:HOH468 4.4 35.1 1.0 CA C:GLU103 4.4 14.9 1.0 CE1 C:TYR36 4.4 18.0 1.0 C6 C:0O2304 4.5 14.2 1.0 N C:SER39 4.5 16.0 1.0 CE1 C:TYR55 4.5 18.5 1.0 N9 C:0O2304 4.6 15.2 1.0 CG2 C:ILE104 4.7 14.9 1.0 CA C:SER39 4.7 15.9 1.0 C4 C:0O2304 4.7 14.0 1.0 OE2 C:GLU103 4.8 20.0 1.0 OH C:TYR55 4.9 20.3 1.0 CE2 C:TYR36 4.9 17.9 1.0 N C:ILE104 4.9 14.4 1.0 CG C:GLU103 4.9 16.3 1.0

Potassium binding site 3 out of 3 in the Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp within 5.0Å range: probe atom residue distance (Å) B Occ D:K302 b:15.2 occ:1.00 O D:GLU103 2.7 13.9 1.0 O D:HOH424 2.7 18.9 1.0 OH D:TYR36 2.8 17.8 1.0 OG D:SER39 2.8 14.0 1.0 O D:HOH419 2.8 15.8 1.0 N7 D:0O2306 3.0 14.5 1.0 O D:HOH429 3.1 21.9 1.0 C8 D:0O2306 3.5 14.7 1.0 CB D:SER39 3.7 14.3 1.0 C D:GLU103 3.8 13.9 1.0 C5 D:0O2306 3.8 13.3 1.0 CZ D:TYR36 3.9 17.2 1.0 OE1 D:GLU103 3.9 17.4 1.0 CD D:GLU103 4.3 16.7 1.0 CB D:GLU103 4.3 14.8 1.0 N D:GLU103 4.3 13.5 1.0 O D:HOH511 4.3 31.6 1.0 O D:SER37 4.3 15.6 1.0 O6 D:0O2306 4.3 12.8 1.0 CE1 D:TYR36 4.4 16.9 1.0 O D:HOH420 4.4 14.6 1.0 CA D:GLU103 4.4 14.2 1.0 C6 D:0O2306 4.5 13.5 1.0 CE1 D:TYR55 4.5 16.9 1.0 N D:SER39 4.5 15.3 1.0 N9 D:0O2306 4.6 14.2 1.0 C4 D:0O2306 4.7 14.1 1.0 CA D:SER39 4.7 14.8 1.0 CG2 D:ILE104 4.7 13.8 1.0 OE2 D:GLU103 4.8 18.3 1.0 OH D:TYR55 4.9 17.0 1.0 CG D:GLU103 4.9 15.1 1.0 CE2 D:TYR36 4.9 17.2 1.0 N D:ILE104 4.9 13.8 1.0

K.Liu, A.R.Myers, T.Pisithkul, K.R.Claas, K.A.Satyshur, D.Amador-Noguez, J.L.Keck, J.D.Wang. Molecular Mechanism and Evolution of Guanylate Kinase Regulation By (P)Ppgpp. Mol.Cell V. 57 735 2015.
ISSN: ISSN 1097-2765
PubMed: 25661490
DOI: 10.1016/J.MOLCEL.2014.12.037