Potassium in PDB 4qne: Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp

All present enzymatic activity of Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp:
1.1.1.205;

The structure of Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp, PDB code: 4qne was solved by J.Osipiuk, N.Maltseva, M.Makowska-Grzyska, M.Gu, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.50 / 2.32
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	121.334, 121.334, 94.470, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 27

The binding sites of Potassium atom in the Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp (pdb code 4qne). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp, PDB code: 4qne:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp within 5.0Å range: probe atom residue distance (Å) B Occ A:K503 b:31.2 occ:1.00 O A:GLY302 2.9 28.8 1.0 O A:GLY304 2.9 35.3 1.0 O A:CYS307 3.0 37.2 1.0 O A:HOH617 3.4 28.8 1.0 C A:CYS307 3.8 35.4 1.0 C A:PRO303 3.9 32.4 1.0 CB A:CYS307 3.9 38.4 0.6 C A:GLY304 4.0 31.7 1.0 C A:GLY302 4.0 30.4 1.0 O A:PRO303 4.0 29.6 1.0 N A:GLY304 4.1 32.7 1.0 N A:CYS307 4.2 35.8 1.0 CA A:CYS307 4.3 36.9 0.6 CB A:CYS307 4.3 37.1 0.4 CA A:PRO303 4.3 30.1 1.0 CA A:CYS307 4.3 36.2 0.4 N A:PRO303 4.6 29.5 1.0 CA A:GLY304 4.7 32.2 1.0 O A:SER305 4.8 36.1 1.0 C A:SER305 4.9 35.4 1.0 N A:THR308 4.9 35.3 1.0 SG A:CYS307 4.9 44.8 0.6 N A:SER305 5.0 31.9 1.0

Potassium binding site 2 out of 2 in the Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp within 5.0Å range: probe atom residue distance (Å) B Occ B:K503 b:34.0 occ:1.00 O B:GLY304 2.7 30.4 1.0 O B:CYS307 2.8 33.6 1.0 O B:GLY302 2.9 30.8 1.0 C B:CYS307 3.7 35.9 1.0 C B:GLY304 3.8 29.6 1.0 C B:PRO303 3.9 34.8 1.0 N B:GLY304 3.9 30.7 1.0 CB B:CYS307 4.0 41.5 0.6 C B:GLY302 4.0 33.4 1.0 O B:PRO303 4.1 34.1 1.0 N B:CYS307 4.2 40.0 1.0 CA B:CYS307 4.2 39.2 0.6 CB B:CYS307 4.3 40.6 0.4 CA B:CYS307 4.3 38.6 0.4 CA B:PRO303 4.3 33.6 1.0 CA B:GLY304 4.5 30.8 1.0 O B:SER305 4.6 32.3 1.0 N B:PRO303 4.7 35.6 1.0 C B:SER305 4.8 32.1 1.0 N B:THR308 4.8 34.3 1.0 N B:SER305 4.8 30.5 1.0 SG B:CYS307 4.9 48.5 0.6

J.Osipiuk, N.Maltseva, M.Makowska-Grzyska, M.Gu, W.F.Anderson, A.Joachimiak. Inosine 5'-Monophosphate Dehydrogenase From Vibrio Cholerae, Deletion Mutant, in Complex with Nad and Imp To Be Published.