Potassium in PDB 4p7g: Rat Apo-Comt, Phosphate Bound

All present enzymatic activity of Rat Apo-Comt, Phosphate Bound:
2.1.1.6;

The structure of Rat Apo-Comt, Phosphate Bound, PDB code: 4p7g was solved by A.Ehler, J.Benz, D.Schlatter, M.G.Rudolph, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.70 / 2.58
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	71.600, 71.600, 393.438, 90.00, 90.00, 120.00
R / Rfree (%)	21 / 24.7

The binding sites of Potassium atom in the Rat Apo-Comt, Phosphate Bound (pdb code 4p7g). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Rat Apo-Comt, Phosphate Bound, PDB code: 4p7g:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Rat Apo-Comt, Phosphate Bound


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Rat Apo-Comt, Phosphate Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:K301 b:74.0 occ:1.00 O A:SER229 2.4 49.5 1.0 O A:PHE232 2.5 49.7 1.0 O A:VAL226 2.6 46.5 1.0 O B:HOH419 2.7 47.0 1.0 O A:ARG227 2.7 56.9 1.0 O B:GLU242 2.8 65.4 1.0 C B:GLU242 3.2 63.4 1.0 C A:ARG227 3.3 55.1 1.0 C A:SER229 3.5 52.2 1.0 CA B:GLU242 3.6 56.6 1.0 C A:PHE232 3.6 51.0 1.0 C A:VAL226 3.7 48.6 1.0 CA A:ARG227 3.7 47.4 1.0 O B:LEU241 4.1 58.0 1.0 N B:TYR243 4.1 60.2 1.0 O A:GLY228 4.2 57.6 1.0 C A:GLY228 4.2 56.4 1.0 N A:ARG227 4.2 47.2 1.0 N A:SER229 4.2 51.2 1.0 N A:GLY228 4.2 52.1 1.0 CA A:PHE232 4.2 48.1 1.0 N A:PHE232 4.3 49.2 1.0 O B:TYR243 4.3 59.6 1.0 SG A:CYS234 4.3 47.5 1.0 CB A:PHE232 4.3 49.7 1.0 N A:SER230 4.3 49.5 1.0 CA A:SER229 4.4 50.6 1.0 CB B:GLU242 4.4 60.0 1.0 CA A:SER230 4.5 48.3 1.0 N A:GLU233 4.6 48.5 1.0 N B:GLU242 4.7 54.4 1.0 C B:TYR243 4.7 63.2 1.0 CA A:GLY228 4.8 52.8 1.0 C B:LEU241 4.8 55.6 1.0 CA B:TYR243 4.8 62.0 1.0 CA A:GLU233 4.9 48.9 1.0 C A:SER230 5.0 51.4 1.0 CA A:VAL226 5.0 44.2 1.0

Potassium binding site 2 out of 2 in the Rat Apo-Comt, Phosphate Bound


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Rat Apo-Comt, Phosphate Bound within 5.0Å range: probe atom residue distance (Å) B Occ B:K301 b:75.9 occ:1.00 O B:SER229 2.4 54.8 1.0 O B:PHE232 2.4 49.0 1.0 O A:GLU242 2.7 73.1 1.0 O B:ARG227 2.7 57.2 1.0 O B:VAL226 2.8 55.9 1.0 O A:HOH428 2.9 35.0 1.0 C A:GLU242 3.1 72.2 1.0 C B:ARG227 3.3 55.7 1.0 CA B:ARG227 3.5 49.0 1.0 C B:SER229 3.5 55.5 1.0 CA A:GLU242 3.6 63.9 1.0 C B:PHE232 3.6 50.9 1.0 C B:VAL226 3.8 54.1 1.0 N A:TYR243 3.9 70.7 1.0 O A:TYR243 3.9 70.0 1.0 O A:LEU241 4.0 57.9 1.0 N B:ARG227 4.2 48.4 1.0 N B:SER229 4.2 50.9 1.0 N B:GLY228 4.3 53.1 1.0 C A:TYR243 4.3 73.1 1.0 SG B:CYS234 4.4 46.4 1.0 CA B:PHE232 4.4 47.2 1.0 C B:GLY228 4.4 54.9 1.0 N B:SER230 4.4 53.0 1.0 CA B:SER229 4.4 50.9 1.0 N B:PHE232 4.4 50.4 1.0 CA A:TYR243 4.5 72.2 1.0 CA B:SER230 4.5 53.4 1.0 CB B:PHE232 4.5 47.4 1.0 CB A:GLU242 4.5 67.0 1.0 N A:GLU242 4.6 60.3 1.0 N B:GLU233 4.7 48.8 1.0 C A:LEU241 4.7 59.5 1.0 OG B:SER229 4.7 56.1 1.0 O B:GLY228 4.8 54.2 1.0 CB B:ARG227 4.8 50.2 1.0 CA B:GLY228 4.8 53.5 1.0 CA B:GLU233 4.9 48.9 1.0

A.Ehler, J.Benz, D.Schlatter, M.G.Rudolph. Mapping the Conformational Space Accessible to Catechol-O-Methyltransferase. Acta Crystallogr.,Sect.D V. 70 2163 2014.
ISSN: ESSN 1399-0047
PubMed: 25084335
DOI: 10.1107/S1399004714012917